Metimazol Flashcards

1
Q

MECANISMO DE ACCIÓN

A

Inhibe la síntesis de hormona tiroidea a nivel de tiroides, actúa como sustrato de la peroxidasa tiroidea, enzima que interviene en la incorporación de yodo en la síntesis de hormonas tiroideas

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2
Q

INDICACIONES CLÍNICAS

A

Hipertiroidismo

Enfermedad de Graves

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3
Q

Pk

A

VO
A: se recomienda ingerir con alimentos o leche
D: Alcanza concentraciones elevadas en la tiroides
M: hepático
E: renal

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4
Q

RAM

A
Rash
Artritis
Pancreatitis aguda
Urticaria
Prurito
Hiperpigmentación cutánea
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5
Q

INTERACCIONES

A

No presenta interacciones de importancia clínica

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6
Q

PRECAUCIONES

A
Anticoncepción
Insuficiencia hepática
Miopatía
Neutropenia
Pancreatitis
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7
Q

CONTRAINDICACIONES

A

Pancreatitis

Pancreatitis aguda

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8
Q

🤰

A

D

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