Micro/Pharm

Question 1

sxs of Rubella vs Roseola

Answer 1

post cerv LAD, Forscheimer spots (petechiae on soft palate & uvula) vs rash on trunk first

Question 2

how to tx tinea? what about tinea capitis specifically? onychomycosis?

Answer 2

terbinafine, if systemic then fluconazole. griseofulvin. terbinafine & itraconazole

Question 3

Lemierre

Answer 3

Fusobacterium -> septic thrombophlebitis in tonsilar v & IJ

Question 4

details ETEC vs EHEC vs EIEC

Answer 4

low osmolar gap vs no fecal leukocytes vs yes fecal leukocytes

Question 5

how to recog Legionella

Answer 5

fever, GI/abd pain, lungs/resp

Question 6

tx nec fasciitis

Answer 6

2 sets blood cx -> broad B lactam/inhib or carbapanem + antiMRSA + clinda; emerg surg/debride

Question 7

dx cryptococcal meningitis. disseminated histo

Answer 7

LP. constitutional sxs, hepatospleno meg, transaminitis, pancyto, LAD; CXR reticulonodular opac

Question 8

AG

Answer 8

block 30S. AE ototox -> deaf in newborn teratogen, nephrotox -> ATN. CI MG

Question 9

TMP/SMX

Answer 9

block dihydrofolate reductase & dihydropterate synthetase. AE T4RTA -> hyperK+, AIN, drug induced lupus, teratogen NTD 1st trim, KERN IN NEONATE, SJS

Question 10

Candida tx & CD4 count & pH

Answer 10

local: azole
severe/systemic: amp B
eso: nystatin, echinocandin/micafungin
disseminated/resistant: capsofungin
CD4 <100, can’t grow under pH 4

Question 11

pseudophed

Answer 11

alpha 1 agonist -> local vasoconstrict in nasal mucosa