Micro test 2 (Table 20.3) Flashcards

1
Q

Inhibitors of Cell Wall Synthesis

A

Natural Penicillins, Semisynthetic Penicillins, Cephalosporins, Polypeptide Antibiotics, Antimycobacterial Antibiotics,

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2
Q

Inhibitors of Protein Synthesis

A

Chloramphenicol, Aminoglycosides, Pleuromutilins, Tetracyclines, Macrolides, Streptogramins, Oxazolidinones, Glycylcyclines,

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3
Q

Injury to the Plamsa Membrane

A

Polymyxin B, Lipopeptides

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4
Q

Inhibitors of Nucleic Acid Synthesis

A

Rifamycins, Quinolones and fluoroquinolones

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5
Q

Competitive Inhibitors of the Synthesis of Essential Metabolites

A

Sulfonamides

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6
Q

Natural Penicillins

A

Penicillin G, Penicillin V

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7
Q

Semisynthetic Penicillins

A

Oxacillin, Ampicillin, Amoxicillin, Aztreonam, Imipenem

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8
Q

Cephalosporins

A

Cephalothin, Cefixime

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9
Q

Polypeptide Antibiotics

A

Bacitracin, Vancomycin

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10
Q

Antimycobacterial Antibiotics

A

Isoniazid, Ethambutol

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11
Q

Aminoglycosides

A

Streptomycin, Neomycin, Gentamicin

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12
Q

Pleuromutilins

A

Mutilin, retpamulin

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13
Q

Tetracyclines

A

Tetracycline, oxytetracycline, chlortetracycline

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14
Q

Macrolides

A

Erythromycin, Azithromycin, clarithromycin, Telithromycin

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15
Q

Streptogramins

A

Quinupristin and dalfopristin

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16
Q

Oxazolidinones

A

Linezolid

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17
Q

Glycylcyclines

A

Tygecycline

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18
Q

Lipopeptides

A

Daptomycin

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19
Q

Rifamycins

A

Rifampin

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20
Q

Quinolones and Fluoroquinolones

A

Nalidixic acid, nofloxacin, ciprofloxacin, Gatifloxacin

21
Q

Sulfonamides

A

Trimethopim-sulfamethoxazole

22
Q

Penicillin G

A

Gram + bacteria, injection (ICWS)

23
Q

Penicillin V

A

Gram - bacteria, oral (ICWS)

24
Q

Oxacillin

A

Resistant to penicillinase (ICWS)

25
Q

Ampicillin

A

Broad spectrum (ICWS)

26
Q

Aztreonam

A

A monbactam; effective against gram-negative bacteria, including pseudomonas spp. (ICWS)

27
Q

Imipenem

A

A carbapenem; very broad spectrum (ICWS)

28
Q

Cephalothin

A

1st gen cephalosporin; activity similar to penicillin; requires injection (ICWS)

29
Q

Cefixime

A

4th gen cephalosporin; oral (ICWS)

30
Q

Bacitracin

A

Gram +; topical application (ICWS)

31
Q

Vancomycin

A

glycopeptide type; penicillinase-resistant; against gram-positive bacteria (ICWS)

32
Q

Isoniazid

A

Inhibitis synthesis of mycolic acid component of cell wall of mycobacterium spp. (ICWS)

33
Q

Ethambutol

A

Inhibits incorporation of mycolic acid into cell wall of mycobacterium (ICWS)

34
Q

Chloramphenicol

A

Broad spectrum, potentially toxic (IPS)

35
Q

Streptomycin

A

Broad spectrum, including mycobacteria (IPS)

36
Q

Neomycin

A

Topical use, broad spectrum (IPS)

37
Q

Gentamicin

A

Broad spectrum, including Pseudomoans spp. (IPS)

38
Q

Mutilin,retpamulin

A

inhibit gram-positive bacteria (IPS)

39
Q

Tetracycline, oxytetracycline, chlortetracycline

A

broad spectrum, including chlamydias and rickettsias; animal feed additives (IPS)

40
Q

Quinupristin and dalfopristin

A

alternative for treating vancomycin-resistant gram + bacteria (IPS)

41
Q

Linezolid

A

Useful primarily aginst penicillin-resistant gram + bacteria (IPS)

42
Q

Amoxicillin

A

Broad spectrum; combined with inhibitor of penicllinase (ICWS)

43
Q

Tygecycline

A

Broad spectrum, especially MRSA and Acinetobacter (IPS)

44
Q

Polymixin B

A

Topical use, gram - bacteria, including pseudomonas spp. (IPM)

45
Q

Daptomycin

A

To treat MRSA infections (IPM)

46
Q

Rifampin

A

Inhibits synthesis of mRNA; treatment of TB (INAS)

47
Q

Nalidixic acid, nofloxacin, ciprofloxacin

A

Inhibit DNA synthesis; broad spectrum; urinary tract infections (INAS)

48
Q

Gatifloxacin

A

Newest gen quinolone; increased potency against gram-positive bacteria (INAS)

49
Q

Trimethoprim-sulfamethoxazole

A

Broad spectrum; combination is widely used (Competitive inhibitor of synthesis of essential metabolites)