Micro Unit 2: Chapter #21

Question 1

Define chamydia

Answer 1

Gram negative membrane with out peptidoglycan

Question 2

Define elementary bodies of the chlamydia life cycle

Answer 2

Ineffective, dormant and will survive outside of cell

Question 3

Define reticulate bodies of the chlamydia life cycle

Answer 3

Non-infective, and replicates by “binary fission”

Question 5

What is binary fission?

Answer 5

Asexual reproduction where DNA is copied + the cell splits

Question 6

What are the 3 diseases caused by C. Trachomatis?

Answer 6

Chlamydiosis, lymphogranuloma, and trachoma

Question 7

MOT of chlamydiosis?

Answer 7

Sexually transmitted

Question 8

MOT of LGV?

Answer 8

Direct, sexually transmitted

Question 9

MOT of trachoma?

Answer 9

During childbirth

Question 10

Define buboes?

Answer 10

Painful, swollen lymph glands near groin

• LGV

Question 11

Give the main long term complications of chlamydiosis in females and males

Answer 11

Females: PID + infertility
Males: epididymitis

Question 12

Give the long term complications of trachoma in babies

Answer 12

Eyelids turn inwards, scarring of conjunctiva

-untreated leads to blindness

Question 13

List the common diagnostic tests for chlamydia

Answer 13

1. Gene probes - most common
2. ELISA
3. Cell structure with direct immunoflourescence

Question 14

Chlamydia clinical manifestations:

Answer 14

Inflammation response— hypersenitivity lll

Question 15

What disease does treponema palladium cause?

Answer 15

Syphilis

Question 16

Treponema define:

Answer 16

Pathogenic for humans only

Question 17

Treponema pallidum pallidum define:

Answer 17

Fastidious organism doesn’t stain well with gram stain

Question 18

Mot of treponema palladium:

Answer 18

Sexual contact

Question 19

Virulent factor of treponema palladium:

Answer 19

Hyaluronidase- responsible for blisters

Question 20

Give the diagnostic procedures for treponema palladium

Answer 20

1.Dark field microscopy: primary

2.Direct immunoflourescence: primary

3.Blood tests: if progressing to stage 2:

Question 21

List the 4 stages of untreated syphilis

Answer 21

1. Primary
2. Secondary
3. Latent
4. Tertiary

Question 22

Primary syphilis

Answer 22

Contagious and infectious in cervix/ exposed areas

Chancre: red lesions

Question 23

Secondary syphilis

Answer 23

Invades blood stream

Generalized rash

Question 24

Latent/clinically inactive syphilis

Answer 24

Lasts 30 years - still infected

Question 25

Tertiary syphilis

Answer 25

Damages tissues/organs by inflammation + hyperimmune response Blindness Gummas: swollen sessions in bone/tissue

Question 26

Syphilis treatment?

Answer 26

Penicillin G, besides tertiary

Question 27

The most commonly reported sexually transmitted disease in the U.S. is caused by bacterium __?

Answer 27

Chlamydia trachomatis

Question 28

Which organism is transmitted via sexual contact?

Answer 28

Trepnoma pallidium pallidium

Question 29

During which stage of syphillis is penicillin in-effective?

Answer 29

Tertiary

Question 30

Historical journals have described gummas. on patients what disease most likely caused these lesions?

Answer 30

Syphillis

Question 31

Describe the phases of untreated syphillis