Microbiology Flashcards

(196 cards)

1
Q

Eukaryote

A

True nucleus, Protozoa

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2
Q

Prokaryote

A

No true nucleus, bacteria

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3
Q

Neisseria

A

Gram negative diplococci, coffee bean shaped

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4
Q

Vibrio

A

Gram negative, Comma shaped

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5
Q

Campylobacter

A

Gram Negative, M/C/C diarrhea

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6
Q

Pseudomonas

A

Blue/Green pus, warm and moist places

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7
Q

Francisella

A

Rabbit Fever

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8
Q

Legionella

A

Water borne

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9
Q

Spirochaetales

A

Treponema, Borrelia, Leptospira (bacteria)

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10
Q

Chlamydiaceae

A

Chlamydia (bacteria)

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11
Q

Mycoplasmataceae

A

Mycoplasma, atypical pneumonia, lacks cell wall, Penicillin stops cell wall synthesis

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12
Q

Rickettsiaceae

A

Spread by insects

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13
Q

Coxiella

A

Spread by milk, Q fever

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14
Q

Hepatitis B Virus

A

DNA virus

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15
Q

Paramyxoviridae

A

Measles, Mumps virus

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16
Q

Coronaviridae

A

Corona virus, SARS in China 2002

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17
Q

Rhabdoviridae

A

Rabies Virus, hydropobia, bullet shaped

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18
Q

Filoviridae

A

Ebola

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19
Q

Reoviridae

A

Polio, Coxsackie

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20
Q

Togaviridae

A

Rubella (German Measles)

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21
Q

Flaviviridae

A

Dengue virus, Yellow fever virus, St. Louis Encephalitis (Jaundice and mosquitos)

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22
Q

Caliciviridae

A

Norwalk virus, causes gastroenteritis,

Seen on cruise ships

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23
Q

IgA

A

Secretory AB
Found in mucous membranes (saliva, tears), Breast milk
8 binding sites

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24
Q

IgD

A

Helps IgG

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25
IgE
Parasitic and allergic infections | Seen in Hodgkin's (Reed-Sternberg Cells)
26
IgG
First to increase at second exposure Most numerous Crosses placenta (Gee ma, thanks!) Anamnestic response (Never forgets)
27
IgM
10 binding sites Largest and heaviest First to increase at first exposure Non-specific
28
Interleukin I
Made by macrophages
29
Interleukin II
Made by CD4 (t-helper) cells
30
Interleukin III
Made by big bone marrow
31
MHC
Self vs. non-self Tissue graft rejection and organ rejection T-cells --> MHC I B-cells --> MHC I and II
32
Staph Aureus Pneumonic
STOIC Scaled Skin Syndrome Toxic Shock Osteomyelitis (M/C/C staph aureus --> hospital staff) Impetigo (honey crusted lesions) Carbuncles (many furuncles --> a carload of furuncles)
33
Strep Pyogenes Pneumonic
``` SERGIS Strep throat Erysipelas --> St. Anthony's fire Rheumatic Fever --> Group A beta hemolytic strep Glomerulonephritis Impetigo Scarlet Fever (Strawberry tongue) ```
34
Complement System
Enhances phagocytosis or cell lysis Classic and alternate pathways meet at C3B C5B-C9 --> membrane attack complex C9 is the end of the system
35
Aschoff Bodies
Rheumatic fever (McCallums Patch)
36
Babes Ernst Granules
Metachromatic granules seen in Diphtheria
37
Downey Cell
Mononucleosis | Don't let Mono get you Down
38
Epithelioid Hystiocyte
TB, Giant epitheloid cell
39
Gohn Complex
TB (inactive phase) | Calcium jail around the mycobacterium
40
Guarneri Bodies
Small Pox (Variola)
41
Gummas
Tertiary Syphilis
42
Koplik Spots
Measles (Rubeola) | On buccal mucosa, white/bluish spots
43
Lipofuscin
Old age pigment | Brown's Atrophy
44
Lewy Bodies
Parkinson's (AKA. Paralysis Agitans)
45
Mallory Bodies
Hepatitis (alcoholism)
46
Negri Bodies
Rabies (hydrophobia)
47
Reed Sternberg
Hodgkin's
48
Russell Bodies
Plasma cells | Multiple Myeloma
49
Natural Active Immunity
Exposed to the disease
50
Artificial Active Immunity
Injection of weakened or dead virus
51
Natural Passive Immunity
Given AB in utero/breastfeeding
52
Artificial Passive Immunity
Injection of preformed AB
53
Endotoxin
Toxin from lipopolysaccharide layer of cell | Heat Stable
54
Exotoxin
Toxin outside the cell from cell waste products | Heat Labile
55
Fomite
inanimate object's as vector
56
Hapten
Partial antigen or half antigen | Does not stimulate immune response
57
Neurotoxin
Toxin that affects the NS (botulism, tetanus)
58
Opsonin
Enhance phagocytosis
59
Prion
Acellular protein which denatures other proteins | Cannot be autoclaved
60
Type I Hypersensitivity
Anaphylactic Bronchial Asthma (allergy) Bee sting, hay fever IgE, Mast cell, Histamine, basophils
61
Type II Hypersensitivity
``` Cytotoxic Goodpasteur's (lung and kidney) Erythroblastosis fetalis (Coombs Anemia) Blood transfusion Myasthenia Gravis IgG 2 things --> Antigen and AB ```
62
Type III Hypersensitivity
``` Immune-complex mediated Lupus, RA Arthus reaction --> local necrosis Serum sickness --> systemic IgG and Complement 3 things --> Antigen, AB and Complement ```
63
Type IV Hypersensitivity
``` Delayed (Cell-mediated) TB Transplant rejeciton Contact dermatitis T-cells, lymphocytes NOT AB MEDIATED ```
64
Autotroph
Inorganic material
65
Heterotroph
Organic material
66
Saprophyte
Dead/decaying animal
67
Parasite
Living organisms
68
Facultative
Presence OR absence of O2
69
Obligate
Must have O2 or Must not have O2
70
Microaerophilic
``` Reduced O2 (high altitude) Candle jar culture ```
71
Symbiosis
one or both benefit
72
Mutualism
Both benefit
73
Synergism
Both benefit and cannot survive without the other
74
Commensalism
One benefits, other is unaffected
75
Zoonosis
Transfer of disease from animal to human
76
Ames Test
Carcinogenicity | Uses Salmonella typhimurium
77
ASO Titer Test
Antistreptolysin O titre | Tests Strep Pyogenes
78
BOD Test
Biological Oxygen Demand | Best test for water pollution
79
Catalase Test
Staph (+) vs. Strep (-)
80
Chick Embryo Culture Test
Virus culture | Cannot grow in agar
81
Chocolate Agar Test
AKA. Thayer Martin Agar or Heated Blood Agar | Gonorrhea
82
Coagulase Test
``` Staph Aureus (+) vs. other Staph (-) Pathogenic vs. non-pathogenic ```
83
Coombs Test
Tests RBC antigens Type II Hypersensitivity Hemolytic anemia, Erythroblastosis fetalis, Rh factor
84
Giemsa Stain Test
Protozoa
85
HLA DR5/CD4
AIDS (ELISA test checks DNA, Western Blot checks proteins) If 2 ELSIA are + --> western blot If western blot + --> AIDS
86
Mannitol Salt Test
Staph
87
Paul Bunnel Test
Heterophile agglutination test for Mono
88
Quellung Reaction Test
Quellung = Swelling | Swelling of capsule of Strep Pneumoniae
89
Sabouraud Agar Test
Test for Fungi
90
Tissue Culture Test
Virus Culture | Cannot grow in agar
91
Weil Felix Test
Serology test Positive for all Rickettsia (EXCEPT Coxiella burnetii --> Q fever) Antigen for test --> Proteus vulgaris
92
Widal Test
Typhoid fever test
93
Tzank Test
Look for altered epithelioid cells Herpes Zoster and simplex Also Varicella
94
Syphilis Tests
Wasserman VDRL Darkfield
95
Tuberculosis Tests
``` Mantous Test --> PPD Tine Test --> skin prick Ziehl Nielson Staining Acid Fast --> My ass is fast Chest x-ray --> Gohn Complex BCG --> mycobacterium bovis Best test --> Sputum culture ```
96
Mononucleosis Tests
Heterophile antibody Heterophile agglutination --> Paul Bunnel Downey Cell --> don't let mono get you down Monospot
97
Sterilization/Autoclave is ineffective against:
Prions
98
Inactivated Vaccination
Salk --> Polio | Rabies
99
Toxoid Vaccination
Tetnus | Botulism
100
Live Attenuated Vaccination
MMR | Sabin --> oral
101
What disease can be acquired post-vaccination?
Guillian Barre (AKA. Post-infectious polyradiculopathy)
102
Case Control Study
Identifies risk factor
103
Double Blind Study
Eliminate placebo effect
104
Retrospective Study
Look back, go back in time
105
Blue/Green Pus
Pseudomonas aeruginosa Un-sanitized hot tub Fluoresces blue under UV light from Pyocyanin and fluorescein pigments
106
Red Pus
Serratia marcenscens
107
White Pus
Chlamydia
108
Yellow Pus
Staph Aureus
109
Yellow/Green Pus
Gonorrhea
110
Iodine
Pre-op disinfectant
111
MRSA
Methycilline Resistant Staph Aureus | Hospitals use Vancomycin
112
Sulfa
Competes with PABA --> Para-amino Benzoic Acid
113
Tetracycline
Inhibits protein synthesis | Turns teeth yellow/brown or gray
114
Ehrlich
First treatment for syphilis
115
Flemming
Discovered Penicillin --> 1928
116
Iwanowski
Discovered the virus
117
Jenner
Developed Smallpox (Variola) vaccine
118
Koch
Anthrax vaccine. | 4 postulates
119
Lister
Antisepsis
120
Pasteur
Father of Pathology/Germ Theory | Rabies Vaccine
121
Pyusner
Discovered Prions --> Mad Cow
122
Reed
Yellow Fever
123
Sabin
Live polio vaccine, oral
124
Salk
Dead polio vaccine, injection
125
Semmelweiss
Wash hands before delivering baby --> reduced puerperal fever (AKA. Childbed Fever)
126
Conjugation
plasmid DNA transfer via sex pilus (bacteria)
127
Transduciton
Bacteriophage transfers genetic material between bacteria
128
Transformation
Direct uptake of free DNA
129
CDC
Stats, not research | Atlanta, GA
130
EPA
Monitors soil, air and water quality | Can't do anything
131
FDA
Regulates health products released to public
132
NIH
Research, not stats | Bethesda, MD
133
OSHA
Makes rules concerning occupational toxicity levels of hazardous materials
134
USDA
Responsible for milk and milk production
135
Emerging
New disease or rapid increase of a disease in incidence of in a geographic range
136
Endemic
Small number of cases in specific location
137
Incidence
Number of NEW cases in a given TIME PERIOD
138
Prevalance
TOTAL number of cases at a particular POINT IN TIME
139
Filtration
Filters big stuff (uses screens) | Primary
140
Flocculation
Aluminum tricholride --> causes clumping to occur | Primary
141
Sedimentation
Precipitate falls | Primary
142
Sludge Digestion
Add anaerobic bacteria | Primary
143
Sand Filtration
Removes Anaerobic bacteria Trickling filter Secondary
144
Aeration
Adds oxygen to water to improve color and taste Kills remaining anaerobic bacteria Decreases BOD Secondary
145
Chlorination
Kills remaining bacteria | Secondary
146
Hymenolepis nana
Dwarf tapeworm
147
Taenia saginata
Beef tapeworm
148
Taenia solium
Pork tapeworm | Cysticercosis
149
Diphyllobothrium latum
May cause B12 deficiency | Freshwater salmon
150
Echinococcus granulosus
Dog tapeworm Also found in wolves Hydatid cyst in live and lung
151
Shistosoma japonicum
Blood fluke Swimmer's itch M/C/C of death by a helminth worldwide
152
Paragonimus westermani
Pulmonary (lung) fluke | Crayfish, mouth
153
Ascaris lumbricoides
Ass is round --> Roundworm M/C roundworm M/C Helminth infection worldwide
154
Wuchereria bancrofti
Filiariasus Mosquito Elephantitis --> lymphatic blockage
155
Necator americanus
Hookworm Fecal contaminated soil Wear shoes to prevent this M/C Hookworm in US
156
Enterobius vermicularis
``` Pinworm (Threadworm) Anus-finger-mouth Scotch tape test Nocturnal M/C Helminth in US ```
157
Onchocerca volvulus
River blindness | Africa
158
Loa loa
River eye worm | African eye worm
159
Trichonella spiralis
Trichinosis Raw pork Lives in striated muscles DX on x-ray --> gastrocnemius
160
Trichuris trichura
Whipworm
161
Capsomere
subunit of the protein coat "capsid" of a virus particle
162
1st virus ever discovered
Tobacco Mosaic Virus
163
Viroid
Single Stranded RNA
164
Virus
DNA or RNA | Contains one or the other, NOT both
165
Arboviruses/Arthropod borne viruses transmission
Mosquitos
166
Polio transmission
Oral/Fecal
167
Hepatitis transmission
``` A = Oral/Fecal B = Sexual transmission C = Transfusions, tattooing, possibly sexual ```
168
Herpes Simplex Type 1
``` Fever blisters (Cold sores) Can be in genome of Trigeminal ```
169
Herpes Simplex Type 2
Genital herpes
170
Herpes Zoster
Shingles in adults Does not cross midline Follows dermatome
171
Molluscum Contagiosum
Pink cauliflower lesion on female genitalia
172
Papovavirus (aka. papillomavirus)
Warts | Casual Contact
173
Rubella
``` German Measles (3-day measles) Most susceptible in 1st trimester ```
174
Rubeola
Red Measles Koplik Spots on buccal mucosa --> white/blusish spots 3 C's = cough, coryza (runny nose), conjunctivitis
175
Vaccinia
Cow Pox
176
Varicella
Chicken Pox | Maculopapularvesicular rash
177
Variola
Small pox Guarneri bodies 1977 = eradicated
178
Coxsackie
B = childhood dysentery | Hand, foot, and mouth disease
179
Hantavirus
spread by rodents, including chipmunks and pairiedogs
180
Polio
Affects anterior horn (alpha motor) | Bulbar type produces respiratory paralysis
181
Adenovirus
Causes conjunctivitis, pharyngitis
182
Influenza
Antigenic shift and/or drift
183
Mumps
Sidomegalic paramyxoid virus parotiditis, leads to LMN disease of CN 7 (Bells Palsy) Sterility from Oophoritis or orchitis
184
RSV
Respiratory Syncytial virus | Croup and Bronchiolitis
185
Rabies
Bullet shaped under electron microscope RNA, rhabdo virus Negri bodies in brain Hydrophobia
186
Reyes Syndrome
Negative reaction to aspirin taken for a viral infection (M/C flu) Fatty liver and encephalopathy Can be fatal
187
AIDS
Reverse transcriptase. RNA --> DNA CD4 cells = T-helper cells Latent persistant infection, allows opportunistic infections
188
Pneumocystis carinii
``` #1 fungal infection in AIDS #1 cause of death in AIDS (from pneumonia) ```
189
Toxoplasmosis
``` #1 parasitic infection in AIDS Spread by cat feces ```
190
Kaposi sarcoma
#1 death by cancer in AIDS
191
Hepatitis A
Fecal/Oral Not a carrier for life RNA Get it and get over it
192
Hepatitis B
Sexual, IV drug abuse Carrier for life Liver cancer (M/C/C) DNA
193
Hepatitis C
Tattoos, blood transfusion Carrier for life RNA Screen blood
194
Hepatitis D
Co-infeciton with Hep B Dane particle Only replicates in presence of Hep B
195
Bubonic Plague (Black Death)
``` Athropod Borne Yersinia Pestis (Pasteurella pestis) Rat flea Bubos = neck and axillary lymph node enlargement Death by asphyxiation ```
196
Tuleremia
Rabbit Fever Frabcusella tularensis Rabbits, squirrels Hunters at risk