Microbiology - exam 2 - antibiotics LF

Question 0

Pen V

Answer 0

phenoxymethylpenicillin
orally bc acid resistant
Streps

Question 1

penicillins

Answer 1

competitive inhibition of transpeptidase (breaks down cell wall)
aerobic G+
anaerobic G- (some)

Question 2

Pen G

Answer 2

bensylpenicillin

Question 3

amoxicillin & ampicillin

Answer 3

broader range than Pen V & Pen G
covers streps, neisseria, haemophilus, E. Coli
can administer Oral, IM, or IV

Question 4

Isoxazolyl peenicillins

Answer 4

methicillin, cloxacillin
FOR bugs that have become resistant to other Beta-Lactams
i.e. Staphs that produce penicillinase

Question 5

clavulanic acid

Answer 5

beta-lactam core (different though bc this one does not bind transpeptidases)
binds penicillinase (which improves susceptibility to B-lactams)

Question 6

cephalosporins

Answer 6

beta-lactam derivatives (Large class) - has a 6 MEMBERED ring instead of 5 like other B-lactams.
variety of targets
given parenterally