MICROPICORNAVIRIDAE

Question 1

GENERAL CHARACTERISTICS
____________ makes DNA copy from genomic RNA; provirus DNA is template for viral RNA. Genetic variablity is common

Answer 1

RNA virus

Question 2

GENERAL CHARACTERISTICS
Similiarities of Lentivirus and HTLV-BLV

both of them has the same MOT

difference
HTLV (Human T-Lympotropic Virus Bovine Leukemia Virus Group)- promotes immortality (_________)
HIV - not _______________

Answer 2

oncogenic virus
not oncogenic

Question 3

characteristics

lipid envelope embedded with trimeric transmembrane glycoprotein ______–

to which the surface glycoprotein _______ is attached

Answer 3

gp41; gp120

Question 4

GENES OF THE HIV

_____ - group specific Ag
______ - polymerase
______ - protease

______ & _______ HIV -1

Answer 4

gag
pol
pro

tat
rev

Question 5

REPLICATION

PRIMARY RECEPTOR
present in ____ positive T helper cells, macrophages, and macroglial cells

the viral glycoprotein _______ binds initially to ______ molecule

Answer 5

CD4; gp120; CD4

Question 6

REPLICATION

Co-receptor, used upon initial infection

Answer 6

CCR5

Question 7

CANCER FROM HIV

HHV8 - _______
EPSTEIN BARR - _______

Answer 7

KAPOSI
BURKITT

Question 8

STAGES OF HIV

Period of asymptomatic infection or a persistent generalized ____________
shift to tropic variants accompany progression to _________

Answer 8

generalized lymphadenopathy
progression to AIDS

Question 9

FULL BLOWN AIDS

CD4 T-cell count of ________

Answer 9

<200/uL

Question 10

MOST COMMON CONFIRMATORY TEST: _________

Answer 10

WESTERN BLOT