mid 1 Flashcards by yuliya krasutska

what is the purpose of the unique ID gievn to the donor

traceback

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what is examined prior to donation

IV drug use armsz

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disinfectant

2% chlorhexidine gluconate and 70% isopropyl

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if allergic to chlorhexidine

isopropyl + iodine

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which bag does the first blood go into

satellite bag

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what is done to avoid clotting as blood is taken

gentle mixing

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how long does blood colelction take place

10 min

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what is autologous

donation to yourself

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autologous

normovolemic hemodilution

type of blood
added to what
stored
longevity
our involment

whole blood
crystalloid or colloid solution to lower hematocrit
RT
8 hrs
does not involve trnsf med

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autologous

intraoperative salvage

what is it
whats done to it
hrs
involment
why is it done

collection the blood that you loose during a surgery and putting it back inside

colelcted from the surgical site, the debri HgB and plasma are removed before put back in

6 hrs

not involved

whne preop collection cnt be done

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autologous

post operative salvage

colelcted from
processing?
involment

from drainige tube
processed or not processed
we may be involved

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autologous

long-term storage
how are they prcoessed
sotrage temp
time

3 reasons

frozen deglycerolized RBC
frozen
10 years

rare phenotype, Ab to a high incidence Ag, multiple Ab

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what must be on the aoutologous label

4 main and 2 side

its only for use for this person

name, PHN or DOB, transfusion facility and biohazard label

indications of use which surgery
contraindications: what they have as disease

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is pre -op autologous hospital smaples have NAT or syphilis testing done

neur

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is pre -op autologous CBS samples have NAT or syphilis testing done

they have evertyhing done, other than syphilis will cause it to be destroeyd

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8 things that donor units are tested for

ABO
Rh
Screen
Heb B surface antigen
anti-HIV 1/2
anti hep C
anti TTLV :hep infection w/ T cell lukemia virus type 11
syphillis

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choice of anticoagulant and whats in it

CPD
citrate, phosphate, dextrose

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what is added to extend shelf life

what is it
whats in it
how long does it extend

SAGM
saline
adenine
glucose
mannitol

42 days

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when is directed donation allowed through CBS

parent to child and its advised against

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how many weeks apart must the donations be

1 week, 4 max

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what sticker is put on direct

direct use only

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what is the family donors blood increase the risk of

graft vs host disease

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can husbands dinate to wives

not recomended especily when she can have kids can make Ab against Ag

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what must happen to the blood donations given by relatives

irradiated

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what is a designated donation 4 reasons for it can it be corssed over to reg use

special donor for special patient -speicfic type of leukocyte or platelets -rare blood type -multiple allo-Ab -regular transfusions -only one that can be corssed over to reg use

apheresis donation what is it

take out the blood and take something from it like the plasma, whites, reds, platelets, hemapoietic progenitor cell and then we return the rest back into the patient

when sagm is added and it increases shell life what temp does it have to stay for that 42 days

1-6C

RBC temp storage

1-6 C

citrate role

antigocoagulant, chelates Ca

dextrose job

needed for the glycolytic path to make ATP

dosium phosphate

buffer, high pH to maintain 2,3 DPG

adenine job

substrate to synthesize ATP, impoves viability

manntitol job

stabilizing agent, prevents hemolysis

what are storage lesions

chemical and physical changes that happen to stored blood

what happens to these as they are stored pH atp 2,3 dpg labiile factors platelet leukocyte potassium

all but K decrease, and K goes up

what dosent survive in whole blood and must be stored seperately 3 things

PLT WBC clotting factors

how soon after donation must RBC be stored away

1 hr

how long does it take to harvest platelets

8 hrs

what must happen to PLT when stored

constant agitation

PLT storage temp

20-24

granulocyte temp

20-24

coagualtion factor storage/ cryoprecipitate

-18 or colder

how soon can RBC need to come back if not used

60 min

what must be done to all RBC product

leuko reduced

what 3 other things can be done to RBC products

SAGM, wasehd, deglycerolized

goal of RBC -LR-SAGM 3 times when we give and 3 times when we dont

increase oxygen carrying capacity blood loss chronic anemia medications that supress bone marrow dont give to those that can be corrected with drugs to correct coagualtion probelms to increase blood suply

RBC -LR-SAGM closed system vs open days and temp

42 days 1-6 24 hrs 1-6 4 hrs >7

RBC-LR-Washed what happens used for 3 not used for

washed with isotonic saline 0.9%, removes plasma, potassium, anticoagulants, and up to 25 % RBC , goal is to remove proteins that can cause a rxn Indications : IgA deficient patients neonates to remove K remove anti-HPA-1 (nocturnal Hgb patients) dont give to those that can be corrected with drugs to correct coagualtion probelms to increase blood suply

RBC-LR-Washed open days and temp

24 hrs 1-6 4 hrs if about 6 (20-24)

RBC - LR- Deglycerolized what is added 2 concentrations and 2 temps

cryoprotectant + glycerol bf frozen: protects internaly and externally 40% @ -65, slow to freeze 20%, @-120 fast to freeze

Deglycerization how is it thawed time to thaw why is glycerol removed how is it removed how many ml in unit Hct inidcations: 4 contradictions

hot bath 10 min removed to prevent hemolysis via a washer 180 mL 0.80 L/L used for rare phenotype multiple Allo-Ab Ab to high incdence Ag severe anaphylactic rxn not used same as rest

deglycerized time storage temp depends on once thawed good fro time nd temp corss match must be done at

10 yrs when frozen temp depends on glycerol content once thawed 24 hrs at 6 4 hrs if 20-24 corss match at IAT

Frozen plasma from what seperated by reduced amounts of factors

from whole blood seperated using a buffy coat reduced factos 5 and 8

if plasma is not LR labeled how much leoco in a bag

>5 x 10^6

storage of plasma frozen vs thawed

frozen : -18, 1 yr thawed: 1-6 120 hrs (5 days)

apheresis fresh frozen plasma how soon must be frozen what factors are there is it leko reduced

8 hrs 5 and 8 not

storage of apherissi FFP frozen thawed sodium citrate thawed

-18 or colder 1 yr 1-6 24 hrs 1-6 120 hrs

use of the plasma

massive hemorage TTP, HUS neonatal exchange emergency not used for : volume, protiens, factors, IgA patients

for plasma is Rh considered

neur

overwrap bag for plasm

for protection from bacteria

pooled platelets, used for

bleeding, due to PLT disoorder or other episodes, and cancer patietns with low PLT

for PLT compatibility is not requreid but

blood group must be known

apheresis PLT used in

refractoriness-HLA matched similar to pooled

storage of pooled PLT / apheresis PLT closed open sys msut be

closed 7 days 20-24 4 hrs 20-24 C agitated

refractoriness 3 reasons

failure to increase even after 2 transufsions removed by spleen : DIC drugs HLA Ab msut be compatible but not speicfic

when Rh- get Rh+ PLT what must be givn

win roh

cryoprecipitate used for / source of

thawed and removal of cryo poor plasma fibrinogen and factor 13 not used for treat hemophilia A, or vWD

cyroprecipitate frozen thawed / pooled

-18C 1 yr 20-24 4 hrs

cryoprecipitate thawed at what temo NaCl at what % how many units pooled

37 c .9 % 8-10

cryosupernantan plasma, LR frozen thawed

-18 1 yr 1-6 120 hrs

albumin storage diff concentrations and what are they used for

stored below 30 25%: liver disease 5%: plasma exchange, burns

Intravenous immune globulin IVIG used for

used to treat viruses taken from plasma protein primary humoral immunodeficeincy ITP secondary hypogammaglovulinemia kawasaki guillian barre syndrom

RhIG stored and used w/ in

from pooled plasma of high anit-D tittre 28 wks, 72 hrs, Rh + PLT 2-8 C 4 hrs after reconstirtuion

HBIG used store

exposure to hep B, 2 wks sexual expos, infants 2-8 C

factot 8 and 9

from pooled plasma 2-8 c

CMV negative RBC

used onlly for intta uterine all blood is filtered and LR and then tested

irradiated product decreased risk of minimu dose

graft vs host in immuno compromised, T lymphs dont attach prevents T replication 25 Gy to central, 15 Gy to the rest

steps to issueing

request slip grab product and inspec tech issues unti by compiter then given to worker / porter blood tag added to unit

what is added to / administrated along with a product

0.9 % NaCl

what should nevr be given together w/ blood

anything w/ calcium or gkucose

what 2 other products can be gien along with RBC

albumin and plasma

is the visual inspection documented

yah

if stoed at X then must be trasnported at y 1-6 20-24

1-10 20-24

RBC must be less than how old to be washed

2 wks

mid 1 Flashcards

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