Mid 1 Flashcards
(22 cards)
Intraneural signals are typically____. Interneural signals are typically ____.
Electrical, chemical
3 Main types of neurons
Sensory neurons, motor neurons, and interneurons
3 ways eukaryotes transport small molecules across the plasma membrane
Diffusion -
movement of ions or molecules from an area of higher concentration into an area of lower concentration
Facilitated diffusion -
proteins in the plasma membrane create a water filled pore for certain molecules to pass through
Active transport -
proteins use ATP to pump molecules against the concentration gradient
What is transmembrane potential energy?
the voltage different across the cell’s membrane. (difference between the voltage inside the cell and outside the cell)
Types of electrical signals within the neuron
Graded Potential-
created near axon hillock. Best for short distances
Action Potential-
created near axon hillock. Best for longer distances
To be a neurotransmitter a chemical must…
- be synthesized in the transmitting neuron
- be released into the synaptic cleft
- bind to the receiving neuron’s receptors in order to change the neuron’s ionic permeability
- be decomposed in the synaptic cleft by enzymes
- bind to the receptors on the presynaptic membrane to inhibit neurotransmitter release
Excitatory & Inhibitory post synaptic potentials
Excitatory increase the likelihood of the neuron creating an action potential inhibitory decrease the likelihood of the neuron creating an action potential.
Action potentials
- first sodium ion channels open, depolarizing the neuron.
- the potassium ion channels open, repolarizing the neuron.
- all action potentials look the same, so it is not about the amplitude of the action potential but about the frequency
- action potentials are faster through mylenated axons
2 types of postsynaptic receptors
lonotropic receptor
- a receptor that contains a binding site for the neurotransmitter, as well as an ion channel that it opened or closed by the neurotransmitter.
Metabotropic receptor
- a receptor that contains a binding site for the neurotransmitter, activating an enzyme that opens an ion channel somewhere else in the neuron
2 ways of terminating the postsynaptic potential
Reuptake
-the removal of the neurotransmitter from the postsynaptic receptor
Enzymatic deactivation
-the destruction of a neurotransmitter with an enzyme
Autoreceptor
- a receptor located on the presynaptic membrane
- typically inhibitory
Narcotic anelgesic agents
- reduce the subjects perception of pain
non-narcotic anelgesic agents
- reduce inflamation
cholinergic agents
- act to increase or decrease acetylcholine or acetylcholinesterase
adenergic agents
- depress either alpha or beta responses
CNS stimulants
- increases norepinephrine
anti-convulsants
- increases Na ions from entering the cell or promotes evacuation
- increases GABA
- decreases acytlcholine
antipsychotics
- blocks dopamine sites
- decreases activity in the medulla
anxiolitics
- alter responses in the limbic center
- increase GABA
psychedelic
-alters cognition or perception
types of hormone secretion
-endocrine
hormones are secreted via the bloodstream
-exocrine
hormones secreted via ducts
-paracrine
hormones diffuse through interstitial space
-pheramone
hormone diffused into the environment
types of propioception receptors
- muscle spindles
- golgi tendon organs
- joint receptors