Midazolam/Versed

Question 1

What is another name for Midazolam?

Answer 1

Versed

Question 2

What is another name for Versed?

Answer 2

Midazolam

Question 3

What kind of drug is Midazolam?

Answer 3

short-acting benzodiazepine

Question 4

What is the onset of Versed?

Answer 4

1-3min IV

Question 5

What is the duration of Midazolam?

Answer 5

2-6 hours, dose dependent

Question 6

What are indications for Versed?

Answer 6

• premedication for intubation, cardioversion, or other painful procedures
• seizures in children when other benzos are not effective

Question 7

What are contraindications for Midazolam?

Answer 7

• hypersensitivity
• glaucoma (relative)
• shock
• coma
• ETOH intoxication (relative; may be used for ETOH withdrawal)
• depressed vital signs
• concomitant use of barbiturates, ETOH, narcotics, or other CNS depressants

Question 8

What are adverse reactions of Versed?

Answer 8

• respiratory depression
• hiccups
• cough
• oversedation
• pain at injection site
• N/V
• headache
• blurred vision
• fluctuations in vital signs
• hypotension
• respiratory arrest

Question 9

What are some drug interactions with Versed?

Answer 9

Sedative effect of Midazolam may be accentuated by use of barbiturates, ETOH, or narcotics

Question 10

How is Midazolam supplied?

Answer 10

2-, 5-, 10-mL vials (1mg/mL)

1-, 2-, 10-mL vials (5mg/mL)

Question 11

What is the dosage for Versed?

Answer 11

Sedation:
Adults: 1-2.5mg slow IV, may repeat in small increments (max dose 0.1mg/kg)
Elderly: 0.5mg slow IV (max dose 1.5mg in 2min period)

RSI:
0.1-0.3mg/kg IV/IO
max single dose of 10mg

Question 12

What are some special considerations for Midazolam?

Answer 12

• pregnancy safety category D
• never administer as IV bolus
• continuously monitor the airway; have intubation and resuscitation equipment readily available