Midterm 1 Flashcards by A B

Q

Benazepril (Lotensin)

A

ACE inhibitor

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Q

Captopril

A

ACE inhibitor

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Q

Enalapril

A

ACE inhibitor

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Q

Fosinopril

A

ACE inhibitor

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Q

Lisinopril

A

ACE inhibitor

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Q

Moexipril

A

ACE inhibitor

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Q

Perindopril

A

ACE inhibitor

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Q

Quinapril (Accupril)

A

ACE inhibitor

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Q

Ramipril

A

ACE inhibitor

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Q

Trandolapril

A

ACE inhibitor

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Q

Azilsartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Candesartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Eprosartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Irbesartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Losartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Olmesartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Telmisartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Valsartan

A

Angiotension-Receptor Blockers (ARBs)

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Q

Aliskiren

A

Renin Inhibitor

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Q

Atenolol

A

Beta Blocker- beta 1 selective

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Q

Bisoprolol

A

Beta Blocker- beta 1 selective

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Q

Carvedilol

A

Beta Blocker

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Q

Labetalol

A

Beta Blocker

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Q

Metoprolol

A

Beta Blocker- beta 1 selective

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Nadolol

Beta Blocker

Nebivolol

Beta Blocker- beta 1 selective

Propranolol

Beta Blocker

Chlorthalidone

Thiazide Diuretics

Hydrochlorothiazide (HCTZ)

Thiazide Diuretics

Metolazone

Thiazide Diuretics

Bumetanide

Loop Diuretics

Furosemide (Lasix)

Loop Diuretics

Torsemide

Loop Diuretics

Amiloride

“Potassium-Sparing” Diuretics

Eplerenone (Inspra)

“Potassium-Sparing” Diuretics

Spironolactone (Aldactone)

“Potassium-Sparing” Diuretics

Triamterene

“Potassium-Sparing” Diuretics

Acetazolamide (Diamox)

Carbonic Anhydrase Inhibitors

Methazolamide

Carbonic Anhydrase Inhibitors

Mannitol (Osmitroll)

Osmotic Diuretics

Amlodipine (Norvasc)

Vasodilators- Calcium Channel Blockers

Diltiazem

Vasodilators- Calcium Channel Blockers

Felodipine

Vasodilators- Calcium Channel Blockers

Isradipine

Vasodilators- Calcium Channel Blockers

Nifedipine (Procardia)

Vasodilators- Calcium Channel Blockers

Verapamil

Vasodilators- Calcium Channel Blockers

Hydralazine

Vasodilator

Minoxidil

Vasodilator

Fenoldopam

Parenteral Agents

Nitroprusside (Nitropress)

Parenteral Agents

Clonidine

Centrally Acting Alpha-2 Agonists

Methyldopa

Centrally Acting Alpha-2 Agonists

Doxazosin (Cardura)

Alpha Blockers

Prazosin (Minipress)

Alpha Blockers

Terazosin (Hytrin)

Alpha Blockers

What is the MOA for ACE inhibitors?

prevent conversion of angiotension I to angiotension II

What is the MOA for Angiotension II Receptor Blockers?

antagonist at AT1 receptor

What is the MOA for Renin inhibitors?

directly inhibits renin (acts earlier than ACE inhibitors or ARBs)

What is the MoA for β-Adrenoceptor (Beta) Blocking Agents?

Lower BP mainly by decreasing cardiac output - Oxygen demand is lowered due to decreased heart rate and force of contraction - Also decrease sympathetic outflow from the CNS and inhibit the release of renin

What is the MOA for Thiazide Diuretics?

Inhibits Na/Cl co-transporter | -Increase concentration of Na and Cl in the tubular fluid

What is the MOA for Loop Diuretics?

Inhibit co-transport of Na/K/2Cl | -Reabsorption is decreased

What is the MOA for Aldosterone antagonists?

Blocks aldosterone receptors Prevents production of proteins that stimulate Na/K exchange sites of the collecting tubules -Prevents Na reabsorption and K/H secretion

What is the MOA for Sodium Blocking channels?

Block sodium transport channels Results in decreased sodium/potassium exchange Does NOT depend on the presence of aldosterone

What is the MOA for Carbonic Anhydrase Inhibitor?

- Carbonic anhydrase catalyzes reaction to form bicarbonate | - CAIs decrease the kidney’s ability to exchange Na for H

What is the MOA for Calcium Channel Blockers?

Block inward movement of calcium Less calcium available to activate contraction Produces reduction in vascular tone Produces dilation of coronary and peripheral arteries Decreases force of contraction and reduces cardiac workload