Midterm

Question 1

Biochemistry

Answer 1

The study of life at the molecular level, application of chem to organic processes

Question 2

Elements of life

Answer 2

C H N O P S

Question 3

Conceptual themes of biochem

Answer 3

Importance of water
Structure/function of proteins
enzyme regulation
kinetics
metabolic reactions, sequences and pathways

Question 4

Major classes of Biomolecules

Answer 4

Sugars
Amino Acids
Fatty Acids
Nucleic Acids

Question 5

Fatty Acids

Answer 5

Monocarboxylic
Saturated or unsturated
components of lipids

Question 6

anabolism

Answer 6

requires energy

Question 7

catabolism

Answer 7

production of energy (degrading macromolecule)

Question 8

Metabolism

Answer 8

sum of chemical reactions happening in a living organism

Question 9

6 Common reactions in biochemical processes

Answer 9

Substitution
addition
elimination
isomerization
redox
hydrolisys

Question 10

How do cells obtain energy

Answer 10

oxidation of biomolecules

Question 11

reaction in spontaneous when DG

Answer 11

negative

Question 12

Properties of water

Answer 12

Cohesion/adhesion
polarity
high specific heat/ heat of Vap
Hydrogen bonding
electronegativity
nucleophilic
solvent

Question 13

what is the Henderson Hasselback equation

Answer 13

pH = pKa + log [A]/[HA]

pH = -log[H+]

Question 14

molarity of water

Answer 14

55.5M

Question 15

what pH range is a buffer effective?

Answer 15

pKa +/- 1

Question 16

what is a buffer composed of

Answer 16

weak acid and conjugate base pair

Question 17

what shape is a titration curve

Answer 17

sigmoidal

Question 18

some buffers in the body

Answer 18

blood plasma
saliva
stomach acid
liver cystol
mitochondrial matrix

Question 19

shape of carbon molecules

Answer 19

tetrahedral

Question 20

Carbon with 4 different sides is

Answer 20

chiral

Question 21

mirror image

Answer 21

enantiomers

Question 22

non-mirror immage

Answer 22

diasteromers

Question 23

Chiral receptor

Answer 23

only has one binding specificity

Question 24

drawing depicting molecules 3-dimensionally

Answer 24

fischer projection

Question 25

amino acid

Answer 25

contains a carboxyl and amino group building blocks of proteins

Question 26

amino acid without chiral centre

Answer 26

glycine

Question 27

ampholyte

Answer 27

act as acid or base

Question 28

zwitterion

Answer 28

have both a positive and neg charge intermediate molecule in titration of AA most amino acids at neutral pH

Question 29

average pKa of carboxyl group

Answer 29

2.19

Question 30

average pKa of amino group

Answer 30

9.47

Question 31

pI

Answer 31

Isoelectric point pH of AA when majority of molecules have no net charge =(pKa1 + pka2)/2

Question 32

Amino Acid properties for classification

Answer 32

hydrophobicity size charge secondary structure preference alcoholicity aromacticity

Question 33

most important character of amino acid

Answer 33

hydrophobicity

Question 34

Amino Acids with positive R

Answer 34

Arginine Histidine Lysine

Question 35

Amino Acids with Neg charged R

Answer 35

Aspartic acid glutamic acid

Question 36

Amino Acids with polar uncharged R

Answer 36

Asparagine Glutamine Serine Threonine tyrosine cysteine

Question 37

Amino Acids with Hydrophobic side chains

Answer 37

Alanine Phenylalanine Isoleucine Leucine Methionine Valine Tryptophan Tyrosine Proline Glycine