Midterm Flashcards
(247 cards)
18 day grace period
no blood transfer if first 18 days, what mom ingests does not affect baby
teratogens
Non genetic
Drugs and chemicals
Infections (eg. rubella)
Radiation
Maternal health conditions (eg. diabetes)
conception
Union of a single ovum and sperm
fertilization
Takes place in fallopian tube
Sperm successfully penetrates the membrane surrounding the ovum
3 stages of pregnancy
Pre-embryonic: fertilization to 3 weeks
Embryonic: weeks 3 to 8
Fetal: weeks 8 to birth
pre-embryonic stage
-fertilization - 3 weeks
- Blastocyst attaches to endometrium and proliferates
- germ layers form
3 germ layers
-ectoderm
-mesoderm
-endoderm
ectoderm
-epidermis, sweat glands, nails, hair, lens of the eye, epithelium, glands
mesoderm
-bones, teeth, muscle, dermis, connective tissue, cardiovascular system, spleen, urogenital system
endoderm
-lining of the resp and GI tract (liver, pancreas, bladder, vagina), epithelium, GUS
Embryonic Stage
- Weeks 3 to 8: Zygote takes human shape = EMBRYO
- Organ systems develop
- Embryo vulnerable to injury by drugs, infections, malnutrition, tetragons
- Most critical time in development
- Placenta forms at implantation
- Functions as an endocrine gland which causes hCG
- hCG detected in maternal serum day 8 to 10
- Metabolic exchange system
- development of structures (chorion, amnion, amniotic fluid, yolk sac, umbilical cord, placenta)
chorion
covering of the fetal side of the placenta
Contains major umbilical blood vessels
amnion
fills with amniotic fluid
amniotic fluid
- baby drinks, digest it, and pee it back out
- test the fluid to see if baby’s kidneys are working properly
- Increases every week
- 700-1000mL at term
- Provides temp control, cushion, oral fluid, repository for waste, freedom of movement, prevents chord from getting tangled, infection barrier
Oligohydramnios
less than 300mL
Associated with fetal renal failure
Polyhydramnios
more than 1000mL
Associated with GI malformations
yolk sac
- Helps with nutrition and oxygenation
- At week 4 it turns into baby’s GI
- Works while placenta forms
umbilical cord
- Rapidly increases in length
- metabolic exchange
- 2 arteries carry blood from the embryo
- 1 big vein brings blood to the embryo
- Wharton’s gelly - prevents cord from collapsing
placenta
- Hormone production (hCG, progesterone, estrogen, relaxin)
- Metabolic exchange
- Week 12 - stops growing
- Week 23 - remodeling
- Function depends on moms bp
- If bp is too high placenta will shut down
- Always check bp
fetal stage
- weeks 8-birth
- Changes are not dramatic and fetus is less at risk for malformations at this stage
- Fetal organs are started and viable to live outside the womb at 24 weeks (+/- 2 weeks) gestation with medical assistance
- Fetal circulation is well developed
- All systems are growing stronger and more complete
dizygotic twins
Fertilization of 2 eggs
Fraternal
2/3
monozygotic twins
Division of one egg
Identical
1/3
complications of twin pregnancies
Often prematures
Spontaneous rupture of membranes preterm
Congenital malformations
Shunting of blood between placenta (one twin gets more blood/nutrients than other)
Congenital heart failure after birth
Higher chance of twins with fertility drugs
Generally a bit smaller than singleton pregnancy (more likely to flip)
twin chorionicity
- Chorionicity scan looks at whether the twins share the same placenta or have separate placentas and whether or not they have 1 chorion or two
- twin to twin transfusion syndrome - if twins share the same placenta, one twin may get more blood and nutrients
- Dichorionic twins do not share circulation