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midterm 2 Flashcards

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1
Q

Atropine

A

Muscarinic Antagonist, inhibits parasympathetic effect (Hint: muscles atrophy, so it’s muscarinic, which sounds like muscle)

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2
Q

phenelzine (Nardil)

A

MAO inhibitor, for clinical depression (Hint: Nardil sounds like a toy for cats)

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3
Q

Scopolamine

A

Muscarinic Antagonist, inhibits parasympathetic effect (Hint: in scotopic lighting, eyes dilate, similar to a sympathetic effect)

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4
Q

MDMA

A

amphetamine-like drug for SERT (and DAT and NET at lower affinities), might help PTSD with psychotherapy

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5
Q

D-tubocurarine (specific)

A

Antagonist, blocks muscle nicotinic receptors, little effect on CNS (Hint: Tubo, don’t smoke! more stupid than Amy)

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6
Q

Hemicholinium-3

A

Blocks Choline Transporter (Hint: cholin)

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7
Q

MHPG

A

NE metabolite

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8
Q

Phenylephrine

A

alpha1 (NE) agonist (Hint: ephrine; phenyl as in fine as in agonist; one i so it’s alpha 1)

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9
Q

muscinol

A

GABA-A agonist (Hint: more muscle to the no)

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10
Q

HVA

A

DA metabolite

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11
Q

phenobarbital

A

Barbiturate (GABA-A) (Hint: barbit)

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12
Q

diazepam (Valium)

A

Benzodiazepine (GABA-A) (Hint: diaze)

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13
Q

SSRI (fluoxetine/prozac)

A

SERT blockers

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14
Q

propranolol

A

beta (NE) antagonist (Hint: the only beta blockers are this and the iso, it is pro but actually lol, so an antagonist)

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15
Q

Baclofen (Lioresal) (specific)

A

GABA-B Agonist, muscle relaxant (Hint: the fens are for GABA B and B is first so agonist)

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16
Q

DOI

A

5-HT2A agonist, hallucinogen (Hint: DOI is so serotonin and hallucinogen vibes, and 2 holes mean 2A)

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17
Q

Physostigmine

A

Blocks AchE

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18
Q

8-OHDPAT

A

full 5-HT1A agonist (stimulates postsynaptic receptors but also reduce 5_HT release through autoreceptors) (Hint: oh, a pat, how calming, and thus it must be serotonin. Only one oh, so 1A)

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19
Q

APV

A

NMDA competitive antagonist (All caps, sounds like a sports competition, and there is only one AMPA/NMDA drug here)

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20
Q

PCPA

A

irreversibly inhibits tryptophan hydroxylase (block 5-HT synthesis) (Hint: it took the P from 5-HTP)

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21
Q

NBQX

A

Glutamate Competitive Antagonist (AMPA and Kainte) (Hint: huge basketball competition energy)

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22
Q

isoproterenol

A

nonselective beta (NE) agonist (Hint: the pro family for beta, but this time, it really is pro and thus an agonist)

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23
Q

haloperidol

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A

antagonist selective for D2-like receptors

24
Q

tricyclic antidepressants

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A

inhibit reuptake of NE and 5-HT

25
Cocaine
inhibit reuptake of all monoamines
26
Black Widow Spider Venom
massive Ach release in PNS
27
Reserpine
blocks VMAT (Hint: It's obvious)
28
Succinylcholine
Nicotinic agonist, resistant to AChE, used to induce depolarization block for muscle relaxant (Hint: its succ to be in surgery)
29
Buspirone
Partial 5-HT1A agonist (stimulates postsynaptic receptors but also reduce 5-HT release through autoreceptors) (Hint: buses don't go all the way, only part of the way. the one is for 1A)
30
MK-801 (dizocilpine)
NMDA non-competitive antagonist (Hint: don't bring a knife to a gun fight. It's not a competition then)
31
L-DOPA
dopamine precursor
32
Ketanserine
5-HT2A antagonist (Hint: serine for serotonin, tan is like made of 2 as in sin and cos = 2A, and ket is the sound of being killed = antagonist)
33
Botulinum toxin
inhibits ACh release selectively in neuromuscular junction
34
Pilocarpine
Muscarinic Agonist, Parasympathomimetic agent, leads to SLUDGE poisoning (Hint: poison vibes)
35
bicuculline
GABA-A competitive antagonist (Hint: cucu = GABA vibes, culling = competitive killing/antagonist)
36
Clonidine
alpha2 (NE) agonist
37
picrotoxin (specific)
GABA-A noncompetitive antagonist (channel pore) (Hint: picro is similar to pico so small like GABA, and a toxin is bad and not a competition so antagonist)
38
Vesamicol
VAChT blocker (Hint: literally says vesicle)
39
apomorphine
agonist for D1 and D2 receptors (Hint: dopamine vibes and apo sounds so positive)
40
tolcapone (tasmar) (specific)
COMT inhibitor, for Parkinson's (Hint: idk tasmar gives comt vibes)
41
Serin
irreversible inhibition of AChE (Hint: Nerve gas)
42
flupentixol
antagonist of D1 and D2 receptors (Hint: picking up a pen need motivation = dopamine, and the flu is bad = antagonist)
43
Methylphenidate (Ritalin)
selective reuptake inhibiter for catecholamines
44
Fenfluramine (Specific)
amphetamine-like drug for SERT, appetite suppressor (Hint: gives firework vibes = transporter going out)
45
WAY-100635
5-HT1A antagonist (Hint: contains 1 and A, but 0 & 0 & 1 = false so antagonist)
46
Ampakines
Positive allosteric modulators of AMPA receptors (Hint: obvious)
47
prazosin
alpha1 (NE) antagonist (Hint: PRAZO has so much energy, its got to be NE; sin is bad so antagonist)
48
Phencyclidine (PCP)
NMDA non-competitive antagonist (Hint: PCP got that competition energy but it's not)
49
ketamine
NMDA non-competitive antagonist (Hint: glutamate vibes, ket = antagonist cause you're dead)
50
Mecamylamine (specific)
Nicotinic Antagonist, blocks nicotinic receptors both in CNS and autonomic ganglia (Hint: AMy don't smoke you're so smart)
51
Saclofen (specific)
GABA-B Antagonist, convulsant
52
AMPT
blocks tyrosine hydroxylase
53
Yohibine
alpha2 (NE) autoreceptor antagonist, increases NE release and induces anxious like behaviours
54
L-AP4
MGluR agonist
55
Fluoxetine
SERT blocker

Drugs (2 decks)

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