Midterm 2 Flashcards
(25 cards)
Normal RBC ct
Men
4.2 - 5.4 million/cubic mg
Normal RBC ct
Women
3.6 - 5.0
million/cubic mg
Overall normal RBC
3.6 - 5.4
million/cubic mg
Normal Reticulocyte
Men
0.5 - 1.5
% of total RBC
Normal Reticulocyte
Women
0.5 - 2.5
% of total RBC
Normal Reticulocyte Index
1.0
Normal Hematocrit (Hct) Men
42 - 52
% of total blood in capillary tube
Normal Hct
Women
36 - 48
% of total blood in capillary tube
Increased Hct d/t?
Severe dehydration
Decreased Hct d/t?
Anemia
Normal Hb
Men
(Same for M/F til age 11)
14 - 18
g/dl %
Normal Hb
Women
12 - 16
Diurnal Rhythm of Hb?
Peaks @ 9am
Lowest @ 8pm
What’s “hemopoesis”?
New RBC creation
Hemopoesis: 0-2 Months?
Yolk Sac
Hemopoesis: 2-7 Months?
Liver
Spleen
Hemopoesis: 5 months?
Bone Marrow starts to function
Hemopoesis: Full-term fetus?
Most all bones are producing RBC
Hemopoesis: Adult?
Skull Vertebra - Sacrum Pelvic bones Sternum Ribs Proximal part of femurs
Erythrocyte Cytoskeleton
“Diameter of RBC”
7-8 micrometers
Diameter of small blood vessels?
2.5 micrometers
**RBCs must be very flexible!!
Erythrocyte Cytoskeleton made up of what 4 things?
Actin
Protein
Alpha/Beta Spectrin
Ankyrin
Look up Ankyrin structure & function
X
Function of erythrocyte cytoskeleton?
Maintains concavity of cell membrane