Midterm 2 quiz questions

Question 1

Which interferes DIRECTLY with platelet aggregation?
 A.  enoxaparin 	
 B.  fondaparinux 	
 C.  abciximab 	
 D.  rivaroxaban 	
 E.  clopidorel

Answer 1

abciximab

Question 2

Which interferes mainly with the extrinsic pathway?
 A.  enoxaparin 	
 B.  fondaparinux 	
 C.  warfarin 	
 D.  prothrombin complex concentrate 	
 E.  clopidogrel

Answer 2

warfarin

Question 3

For which drug is the aPTT test appropriate?
 A.  heparin 	
 B.  warfarin 	
 C.  clopidogrel 	
 D.  dabigatran 	
 E.  abciximab

Answer 3

heparin

Question 4

Which test is sensitive to the anticoagulant effect of a VKOR inhibitor?
 A.  aPTT 	
 B.  PT 	
 C.  INR 	
 D.  Both A and B 	
 E.  Both B and C

Answer 4

Both B and C

Question 5

Which is used to treat overdose of some second drug?
 A.  naloxone 	
 B.  protamine 	
 C.  Vitamin K 	
 D.  All of the above 	
 E.  None of the above

Answer 5

All of the above

Question 6

Which is TRUE of nitrous oxide at 1 MAC?

A.
Half the subjects DO respond to surgical incision.

B.
The administered gas mixture is anoxic.

C.
Half the subjects DO NOT respond to surgical incision.

D.
All of the above.

E. None of the above.

Answer 6

All of the above.

Question 7

Please identify the drug that reverses or shortens the duration of local anesthesia by blocking alpha-adrenergic receptors.

Answer 7

Phentolamine

Question 8

Please identify the treatment or drug that would be UNLIKELY to improve oxygenation of the cardiac wall supplied by a coronary artery which is significantly narrowed by atherosclerotic plaque

Answer 8

Isoflurane anesthesia

Question 9

The pathological ventricular remodeling associated with Congestive Heart Failure is thought to be most effectively treated with:

Answer 9

Angiotensin II receptor (AT1) antagonists

Question 10

Digoxin increases cardiac contractility by

Answer 10

inhibiting sarcolemmal Na/K-ATPase, leading to an increase in intracellular calcium

Question 11

Please identify the drug that is likely to be most effective in preventing arrhythmias triggered by EMOTIONAL STRESS.

Answer 11

Class II antiarrhythmic drugs

Question 12

Select the one drug that is specific for COX-2
 A.  ibuprofen. 	
 B.  acetaminophen. 	
 C.  salicylic acid 	
 D.  celecoxib. 	
 E.  naproxen 	
 F.  none of the above

Answer 12

Celecoxib

Question 13

When prescribing anti-hypertensive medication to a patient who suffers from ASTHMA, you should definitely avoid:

Answer 13

Propranolol

Question 14

The best drug choice for hypertensive emergencies in pregnant women would be:

Answer 14

Hydralazine

Question 15

Which anti-hypertensive drugs should be withdrawn immediately upon learning that the patient is pregnant?

Answer 15

Losartan

Question 16

Please identify the drug that is most likely to enhance the hypotensive effect of Enalapril.

Answer 16

Hydrochlorothiazide

Question 17

You should always be prepared to handle a sudden rise in blood pressure as a result of epinephrine (in local anesthetics) getting to the systemic circulation. However, the risk of such hypertensive emergency is particularly high in patients treated with:

Answer 17

Non-selective beta-adrenergic antagonists

Question 18

parasympathomimetic will have which effect? [LO 6.1 and 6.2]
A: positive chronotropic effect
B: positive inotropic effect
C: bronchodilating effect
D: all of the above
E: none of the above

Answer 18

E: none of the above

Question 19

In a patient with both asthma and angina, which drug combination may be expected to exacerbate BOTH
conditions?

A: isoproterenol and propranolol
B: albuterol and metoprolol
C: albuterol and propranolol
D: isoproterenol and metoprolol
E: None of the above.

Answer 19

isoproterenol and propranolol

Question 20

The maximum dose of 0.5% bupivacaine with epinephrine 1:200,000 is:

Answer 20

1.3 mg/kg

Question 21

The amount of epinephrine in 1 carpule of 2% lidocaine with epinephrine 1:100,000 is

Answer 21

.018 mg

Question 22

Of the following local anesthetics, which provides the longest acting nerve blockade?

A: 0.5% bupivacaine with epinephrine 1:200,000
B: 2% bidocaine with epinephrine 1:100,000
C: 3% mepivacaine
D: 4% articaine with epinephrine 1:100,000

Answer 22

0.5% bupivacaine with epinephrine 1:200,000

Question 23

Time of onset of local anesthesia is determined by

Answer 23

The pKa of the local anesthetic.

Question 24

The mechanism of action of local anesthetics is that they:

Answer 24

block influx of sodium.

Question 25

Which drug is associated with risk of inducing torsades do pointes?

Answer 25

Sotalol

Question 26

Stim effects of epi on heart are blocked by what

Answer 26

Propanolol

Question 27

Which drug category obscures endogenous neuronal firing patterns?

A. receptor agonists
B. neurotransmitter reuptake inhibitors
C. receptor modulators (e.g., benzodiazepine)
D. Both A and B
E. Both B and C

Answer 27

receptor agonists

Question 28

The INR is reliably used to monitor the effects of .

Answer 28

warfarin

Question 29

Which is an irreversibly-acting antiplatelet agent?

A. acetylsalicylic acid
B. clopidogrel
C. GPiib/IIIa
D. Both A and B
E. Both B and C

Answer 29

Both A and B

Question 30

Identify the anticoagulant which does NOT inhibit Xa.

A. Dabigatran
B. heparin
C. rivaroxaban
D. apixaban
E. edoxaban

Answer 30

Dabigatran

Question 31

Heparin is used for in-patient anticoagulant therapy because

Answer 31

bioavailability is 0%

Question 32

For a half-century, warfarin was the only choice for out-patient anticoagulant therapy. From
which attribute does warfarin’s long popularity mainly derive?

Answer 32

bioavailability is 100%