Midterm Flashcards

(131 cards)

1
Q
  1. Leukoplakia
A
  • An intraoral white plaque that does not rub off and can not be identified as any well known entity.
  • If it can be rubbed off, it is not Leukoplakia
  • If it is easily recognizable as a well known entity, it is not Leukoplakia.
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2
Q

What are the five white lesions that CAN be scraped off?

A
  • Materia Alba
  • White coated tongue
  • Burn (thermal, chemical, cotton roll, etc.)
  • Pseudomembranous candidiasis
  • Toothpaste or mouthwash overdose
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3
Q

Does white coated tongue cause pain, and how do you treat it?

A
  • Asymptomatic

* Treatment is tongue scraping or brushing

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4
Q

How do you treat leukoplakia?

A

When in doubt, cut it out.

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5
Q

What could leukoplakia look like on the histology slide?

A
  1. Hyperkeratosis
  2. Dysplasia
  3. Carcinoma-in-situ
  4. Invasive squamous cell carcinoma
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6
Q

Where are the three most common locations of leukoplakia?

A
  1. Floor of mouth
  2. Tongue
  3. Lip
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7
Q

What is the best guide to potential progression of oral lesions?

A

Degree of dysplasia

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8
Q

What is the percentage transformation rate of severe dysplasia?

A

16%
• Mean transformation time 4.3 years
• Histologic grade significantly affected rate
• Excision significantly decreased rate

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9
Q
  1. Tori
A
  • Torus Palatinus: 20-35%, 2F:1M, C=B

* Torus Mandibularis: 7-10%, M>F, C=B, 90% bilateral

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10
Q
  1. Inflammation or Irritation
A

Traumatic Ulcer
Pericoronitis
Periodontal Abscess (Parulis)
A.N.U.G.

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11
Q
  1. Fibroma
A
  • MOST COMMON BENIGN NEOPLASM OF THE ORAL CAVITY
  • Buccal mucosa > labial mucosa > tongue > gingiva
  • Surgical excision
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12
Q
  1. Fordyce Granules
A
  • Ectopic sebaceous glands
  • 80% of the population
  • yellowish white papules
  • buccal mucosa > lips
  • no treatment
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13
Q
  1. Hemangioma
A
  • Benign proliferation of blood vessels
  • 10 - 12% of children
  • Clinically blanches under pressure
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14
Q
  1. Inflammatory Ulcer (Recurrent Aphthous Ulcer)
A
  • Affects 20-25% of the population
  • Non-keratinized, non-bound down mucosa
  • 1-2 lesions, .5-1 cm in diameter
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15
Q

How do you treat hemangiomas?

A

• Treatment – surgery, laser, embolization, Clinical Observation, Removal, Sclerotherapy

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16
Q

How do you treat recurrent aphthous ulcerations?

A

• Treatment – Topicial Steroids

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17
Q

What is the etiology of recurrent aphthous ulcers?

A

• ETIOLOGY: “Different things in different people”. Autoimmune THEORY, Hypersensitivity THEORY, Stress THEORY, etc THEORY.

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18
Q

What are the prescriptions for recurrent aphthous ulcers?

A

• PRESCRIPTIONS: Aphthasol, Betamethasone, Temovate, Decadron, Lidex, Kenalog, Medrol, Etc.

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19
Q
  1. Papilloma
A

• Benign proliferaJon of squamous epithelium (HPV ?)
• Tongue > Soft palate
• Solitary pedunculated
wart-like

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20
Q

How do you treat papillomas?

A

• Treatment - Surgical excision

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21
Q

What are the variations of papillomas?

A
  • Verruca Vulgaris (wart),
  • Condyloma Acuminatum (Venereal wart),
  • Focal Epithelial Hyperplasia (Heck’s Disease),
  • Sinonasal Papillomas
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22
Q
  1. Epulis Fissuratum
A

Focal inflammatory hyperplasia at the flange of an ill-fitting denture. Single or multiple folds of tissue in the vestibule.

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23
Q

How do you treat epulis fissuratum?

A

Surgical excision, reline or remaking the denture

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24
Q
  1. Varicosities
A

Pretty normal

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25
11. Fissured Tongue
* Numerous grooves or fissures on the dorsal tongue, 2-6 mm deep. * Cause ??? Heredity? * 2 - 5% of the population, increasing with age * Mild burning or soreness sometimes * Treatment - Brush the tongue
26
12. Geographic Tongue
* “Erythema Areata Migrans”, “Benign Migratory Glossitis” * 1 - 3% of the population, 2F>1M * Dorsal tongue, rarely ventral * Asymptomatic with rare cases of sensitivity to hot or spicy foods * No treatment
27
13. Papillary Hyperplasia
* Denture papillomatosis * 20% of the patients who wear their dentures 24 hours a day * Hard palate, pebbly surface * Asymptomatic
28
How do you treat papillary hyperplasia?
• Treatment - surgical excision (scapel, electro-, cryo-, laser-surgery) then reline or remake of the denture
29
14. Herpes Viral Infection
Recurrent Herpes Simplex • Almost ALWAYS on keratinized, bound mucosa (palate, attached gingiva) • Symptoms are less intense • Lesions begin as 1-3 mm vesicles – Rapidly collapse to form a cluster of erythematous macules that coalesce and slightly enlarged – Damaged epithelium is lost – Central, yellowish area of ulceration – Heals in 7-10d * Acute herpetic gingivostomatitis: Initial exposure between 6 months - 5 years of age * Recurrent herpetic infections: herpes labialis, intraoral recurrent lesions, herpetic whitlow, herpetic keratoconjunctivitis
30
What are the antiviral medications for herpes?
* Acyclovir 5% ointment (Zovirax), 15 gm tube, apply 5 times a day with fingercot at first symptom * Acyclovir 200mg. capsules, dispense 50, 1 cap 5 x daily * Famciclovir (Famvir) 125 mg tablets, bid for 5 days. * Penciclovir 1% (Denavir) Cream, 2 gm tube, apply q2h. * Prodromal stages is best time to start treatment (Use VIROXYN) * Prophylaxis: Lysine 500 mg tab. QD
31
15. Mucocele
* Rupture & spillage of saliva into the soft tissues * Young adults, trauma related * Lower lip - most common location * Treatment - Surgical excision along with the feeder gland
32
16. Scar Tissue
* Post trauma locations * Post surgical locations * Treatment - none
33
17. Angular Cheilitis
• Causes: Reduced vertical dimension, salivary pooling, candidiasis
34
How do you treat angular cheilitis?
• Treatment: antifungals, increase the vertical dimension
35
18. Lingual Tonsil
* Lymphoid hyperplasia on the posterior lateral borders of the tongue, bilateral * Discrete 1 cm masses which enlarge and turn red with infection * Treatment: none
36
19. Hematoma
* Accumulation of blood within the tissues secondary to trauma * Treatment: none
37
20. Tobacco Pouch Keratosis
• Soft, fissured gray-white lesion of the mucosa located in the area of chronic snuff placement • Histologic appearance varies based upon duration • Treatment: Cessation of “dipping” If use continues, results may progress from Dysplasia to Verrucous Carcinoma (cauliflower)
38
21. Chronic Cheek Biting
* Morsicatio buccarum, labiorum, linguarum * 2F:1M * Irregular ragged white mucosa * Treatment: none or bite guard
39
22. Lichen Planus
Oral lichen planus must be differentiated from lichenoid drug reactions, and there are dozens of drugs that can cause it. • Chronic mucocutaneous disease • Middle aged, 3F:2M • Skin lesions: purple, pruritic, polygonal papules • Oral lesions: Reticular (Striae of Wickham), Erosive
40
What are the two forms of lichen planus?
Reticular and Erosive
41
How do you treat lichen planus?
• Treatment: Steroids • Aphthasol 5%, 5 gm tube, apply to ulcer • Betamethasone (Celestone) Syrup, dispense 8 oz., 1 tsp qid, gargle & expectorate. • Temovate .05% ointment, 15 tube • Decadron Elixir 0.5mg/5ml, Rinse & expectorate. • Lidex 0.05% ointment or gel • Medrol Dose pack
42
23. Buccal Exostoses
* Bony protuberances on the buccal of the mandible and/or maxilla * Treatment: Removal only with chronic repeated trauma or preprosthetic surgery
43
24. Amalgam Tattoo
* Implantation of dental amalgam into oral soft or hard tissue * Black, blue or grey in soft tissue tattoos * May be radiopaque * Treatment: none, however biopsy may be necessary to rule out melanoma
44
25. Oral Melanotic Macule
``` • Focal Melanosis (“oral freckle”) • Solitary well-demarcated tan to dark brown macule, 1-7 mm • 2F:1M • Lower lip > buccal mucosa > gingiva • Treatment: none, however biopsy may be indicated to rule out melanoma ```
45
26. Median Rhomboid Glossitis
* Central papillary atrophy of the tongue | * Asymptomatic erythematous zone in the midline posterior dorsal tongue
46
How do you treat median rhomboid glossitis?
• Treatment: antifungals and brushing of the tongue
47
27. Black Hairy Tongue
Condition is usually asymptomatic, but occasional patients complain of: Gagging sensation, Bad taste, Halitosis, Esthetics
48
28. Smooth Red Tongue
* Causes: Pernicious anemia, Medications, Avitaminosis * Symptoms: burning and pain * Treatment: find the underlying cause and stop it
49
29. Epidermoid Cyst
* Skin cysts associated with inflammation of a hair follicle • Oral cysts occur in the midline of the floor of the mouth • Slow growing, painless, rubbery mass * Treatment: Surgical removal
50
30. Lipoma
* Benign tumor of fat * Skin lesions: trunk and proximal portions of the extremities * Oral lesions: buccal mucosa > tongue > floor of the mouth > lips * Yellowish soft nodular mass * Treatment: Surgical excision
51
What are the characteristics of white lesions?
``` Thickened epithelial covering - Hyperkeratosis, acanthosis, dysplasia, carcinoma Decreased vascularity - Anemia Increased collagen - Submucous fibrosis ```
52
When we are describing lesions, what five characteristics should we describe?
1. Size 2. Morphology 3. Location 4. Texture 5. Color - A fibroma is a 2 mm sessile nodule on buccal mucosa, smooth surfaced, and pink in color
53
What are the characteristics of red lesions?
Thinner epithelium Increased vascularity A dissolution of the collagen content of the subepithelial tissue
54
What is another name for Wright's lesion?
Localized spongiotic gingival hyperplasia
55
If you blanch a lesion and blood goes away, then it is not a hematoma. True or False?
True
56
What are the characteristics of blue lesions?
Venous blood collection as opposed to the red of arterial blood collection Tyndall effect Medications
57
What are the characteristics of black lesions?
Melanin: a pigment produced by cells called melanocytes, acts as a sunscreen and protects the skin from ultraviolet light Heavy metals: amalgam, iron, bismuth
58
What are the characteristics of brown lesions?
Melanin | Hemosiderin: a yellowish brown granular pigment formed by the breakdown of hemoglobin, found in phagocytes
59
What are the characteristics of yellow lesions?
Adipose tissue Sebaceous material (skin oil) as noted in fordyce granules Pus as it is a collection of necrotic material, PMNs, and lymphocytes
60
What is the order of the most common colors found abnormally in the oral cavity?
Most to Least: 1. White 2. Red 3. Black 4. Blue and Yellow (Tie)
61
What do you do if you see a white lesion in the mouth?
First thing you do is try and rub it off, if it does come off, then it is probably one of those five things. If it doesn't, than could be leukoplakia. Remove obvious frictional causes, and biopsy after two weeks
62
If you see inflamed red gums, what is the initial clinical diagnosis, and how can you treat it?
Desquamative gingivitis. The differentials are mucous membrane pemphigoid, pemphigus, allergies, and rarely SLE. - Biopsy for confirmation, and then you can use topical steroids.
63
If you notice lichen planus on a patient, how can you differentiate it from psoriasis?
Ask them if they have itchy skin lesions on rest of body. If they do, that's not psoriasis.
64
What is Dr. Trump's "go to" therapy for lichen planus?
Topical steroid application. He likes Clobetasol Propionate Gel (Temovate) 0.05%. 15 or 30 gram tube. Have them dry the infected area, gently massage a thin amount two to three times a day.
65
When do you use pastes vs creams vs gels vs all over mouth vs just one area?
Pastes and creams are more for skin, gel more for mouth. Paste is an option for the mouth but cream is not. If all over the mouth, use a rinse instead of a gel, or if it is on the soft palate.
66
What are the prescriptions Dr. Trump likes to give for lichen planus and recurrent aphthous ulcers?
Fluocinonide (Lidex) - 0.05% gel - 15 or 30 gram tube - Dry the affected area and gently apply a thin amount 2-4 times daily, depending on how bad it is. - Has moderate potency (not yet proven with FDA) Clobetasol Proprionate (Temovate) - 0.05% gel - 15 or 30 gram tube - Dry the affected area and gently apply a thin amount 2-3 times daily - Has high potency Dexamethasone Elixir (Decadron) (Is a Rinse) - 0.5mg/5ml - 12-16 oz (about 500 ml or .5 liters) - Rinse with 1 tsp. for 2 minutes 2-4 times daily and expectorate - Has moderate potency - Tell them that it is a solution and you want 0.5mg/5mL - Give them enough to give them a few months of comfort, but then they will get back in to get more. -For a rinse, he does 3 refills, for Temovate he only does 1
67
What are the eight white plaques that do not rub off in the mouth, and how do you treat them?
1. Leukoplakia - Biopsy 2. Linea Alba - Nothing 3. Leukoedema - Nothing 4. Chronic Cheek Chewing - Bite Guard 5. Nicotine Stomatitis - Discontinue 6. Tobacco Pouch Keratosis - Discontinue 7. Lichen Planus - Steroids 8. Oral Hairy Leukoplakia - Treat AIDS
68
What are some of the prescriptions for recurrent aphthous ulcers (red and white lesions)?
Aphthasol Dexamethasone Temovate (Clobetasol Proprionate) Lidex
69
What can you use on TUGSE when topicals don't work?
``` Intra-lesional injections. Kenalog 10 (10 mg/ml) Kenalog 40 (40 mg/ml) - 1 ml for every 1 cm of tissue - 10 mg per cm of lesional tissue - 1 ml of Kenalog 10 or 0.25 ml of Kenalog 40 ```
70
What are the various forms of candidiasis?
``` White pseudomembranous Erythematous - Central papillary atrophy of tongue (Median Rhomboid Glossitis - Angular Cheilitis - Denture Stomatitis ```
71
What are the four forms that antifungals come as?
1. Rinse 2. Troche 3. Tablet 4. Cream/ointment
72
What is the best treatment for angular cheilitis?
Mycolog II - 0.1% Triamcinolone and Nystatin 100,000 units/gram ointment. - in 15 gram tube, - used sparingly to affected areas qid (There is also just a nystatin ointment that is dispensed the same way)
73
How is nystatin oral suspension administered?
Nystatin (Mycostatin) oral suspension (100,000 units/ml) - Dispense 180 ml - Rinse with 1-2 tsp for 3-4 minutes qid and expectorate, unless affecting soft pharynx, then swallow - Remember not to use the rinse with dry mouth or severe caries because this has sugar. Use Clotrimazole (Mycelex) troche in this case.
74
What is the name of the antifungal troche?
Clotrimazole (Mycelex) Troche 10 mg - This is used when patients hate the rinse - Dispense 50 - Dissolve one troche 5 times a day. Let it dissolve in mouth
75
Hematomas clinically blanch under pressure. True or False?
False, neither does petechiae. Hemangiomas will blanch under pressure though. And you treat them with surgery, laser, or observation.
76
Where is erythroplakia most commonly found?
Floor of mouth, tongue, and soft palate | - 90% are histologically severe dysplasia, Ca in situ, or squamous cell carcinoma
77
What is oral melanoacanthoma and how do you treat it?
``` Acquired pigmentation Reactive process due to trauma Seen almost always in blacks Most common in females in 20 to 30s Buccal mucosa Lesions increase rapidly in size Incisional biopsy to rule out melanoma ```
78
What are the typical red lesions?
1. Erythematous candidiasis 2. Angular cheilitis 3. Lingual tonsil 4. Hemangioma 5. Hypersensitivity reaction 6. Erythroplakia
79
What are the typical black lesions?
1. Racial pigmentation 2. Amalgam Tattoo 3. Oral melanotic macule 4. Intramucosal nevus 5. Oral Melanoacanthoma 6. Malignant Melanoma
80
What are the typical blue lesions?
1. Blue nevus 2. Varicosities 3. Hemangioma 4. Mucocele/Ranula 5. Salivary duct cyst 6. Mucoepidermoid carcinoma
81
What is a granular cell tumor?
Benign soft tissue neoplasm that shows a predilection for the oral cavity Most common site is the tongue (up to 50%) – Dorsal surface Asymptomatic, sessile nodule that is less than 2 cm May be yellow or mucosal-colored African American patients may experience multiple tumors
82
What are the typical yellow lesions?
1. Fordyce granules 2. Lymphoid hyperplasia (lingual tonsil) 3. Gum boil (Parulis) 4. Lipoma 5. Granular Cell Tumor
83
What are the main medications that cause xerostomia?
Anti-depressants, beta blockers, sleeping aids
84
What does biotene and mouth kote help treat?
Xerostomia
85
What are tips for patients with xerostomia?
1. Sip water throughout the day 2. Suck on ice (do not chew) 3. Discontinue alcohol, caffeine, soda 4. Humidifier at night 5. Lubricate lips (lanolin) 6. Fluoride supplementation
86
What is the prescription for xerostomia?
PIlocarpine (Salagen) - 5 mg tablets - Dispense 90 tablets - 5 mg three times a day for first month, and then titrating to maximum dose of 30 mg per day depending upon response and tolerance - Approved for tx of dry mouth from radiation/chemotherapy. Sjogren's Syndrome - Medications with anticholinergic effects counteract - Benadryl, some antidepressants - Biggest side effect is sweating
87
What can we use for dry lips?
1. Chapstick 2. Aquaphor 3. Blistex complete 4. Lanolin
88
What are the main prescriptions for herpetic infections?
Acyclovir (Zovirax) - Caps and ointment - 200 mg, dispense 50, 1 cap 5 times a day - 5% ointment, dispense 15 gram tube, apply to affected area 5 times a day with fingercot Famciclovir (Famvir) - 125 mg tablets - Dispense 10 tablets, take 1 tablet twice daily for five days
89
What can cause burning mouth?
1. Lubrication 2. Candidiasis treatment 3. Nutritional treatment (B12, folate, iron, zinc) 4. Diabetic control 5. Eliminate triclosan/tarter control products 6. Switch hypertensive medication if on ACE-inhibitor 7. Clonazepan 0.5 mg tablet. Start with dissolving half a 0.5 mg tab twice daily and slowly increase to 1 mg twice a day 8. Alpha Lipoic Acid 9. Capsaicin
90
What is needed for a prescription of a controlled substance?
* Mustbedatedandsignedondayofissue * Patient’sfullnameandaddress * Practitioner’sfullnameandaddressandDEA# * Drugname * Strength * Dosageform * Quantityprescribed * Directionsforuse * Numberofrefills(ifany) * Writteninink,indeliblepencil,ortypewritten * Manually signed Schedule II controlled substances • Requirewrittenprescription • Nofederaltimelimittofill • Nospecificfederallimitstoquantities(somestatesand insurance carriers limit to 30-days) • Refillsprohibited • Multipleprescriptions(90days)permitted(conditions exist) • Facsimile(fax)prescriptionsokforpreparationonly (original must be presented for dispensing) • Emergencyphoneprescriptiononlyforquantitytocover emergency period provided original prescription received within seven days
91
What are some examples of schedule II narcotics?
hydrocodone products like Vicodin & Norco oxycodone (OxyContin®, Percocet®), and fentanyl (Sublimaze®, Duragesic®).
92
Prescriptions for schedule lll, lV and V may be oral, written, or faxed, and refills are ok and can be done by call-in. True or False?
True
93
What is in the superscription of a classical prescription?
Superscription—patient’s name,address, date and Rx (recipe)
94
What is in the inscription of a classical prescription?
name of drug, dose form, and quan0ty
95
What is in the subscription of a classical prescription?
directions to pharmacist
96
What is in the transcription of a classical prescription?
directions to patient
97
What does a modern prescription look like?
Heading—name and address and phone # prescriber --name and address of the patient --date of prescription Body—Rx symbol --name, form (tablet) and dosage size or concentration of drug --amount or quantity --directions to patient --"Disp: 20 tabs" --"Sig: 1 tab q4h prn pain"
98
Twice a day
bid
99
with
c
100
capsule
cap
101
before meals
ac
102
dispense
disp
103
gram
gm
104
grain
gr
105
drop
gtt
106
hour
h
107
at bedtime
hs
108
number
no
109
no refill, do not repeat
non rep
110
after
p
111
after meals
pc
112
by mouth
p.o.
113
as needed
prn
114
every
q
115
every day
qd
116
4 times a day
qid
117
without
s
118
write (label)
sig
119
immediately
stat
120
tablet
tab
121
3 times a day
tid
122
When is prednisone used and what is the prescription?
For autoimmune or vesicular bolus, pemphigoid, pemphigus, lichen planus after gel proved not to work. This is systemic. Prednisone 10 mg tab Disp: 40 Sig: 2 tabs bid x 7d, then 1 tab bid x 4d, then 1 tab daily til gone
123
What two things are used for sores in mouth, sore throat, or anything to just soothe the mouth?
Xylocaine Viscous 2% Disp: 100ml sig: Rinse with 1 tsp as needed and spit out Magic Mouthwash -Equal parts maalox, benadryl, and xylocaine viscous 2%. This will help soothe and numb the mouth.
124
What is the brand name of nystatin oral suspension?
Mycostatin
125
What is the brand name of Clotrimazone troche 10mg?
Mycelex
126
What is the brand name of Nystatin/triaincinolone acetonide ointment?
Mycolog II
127
What is the brand name for acyclovir caps 200mg?
Zovirax
128
What is the brand name for Fluocinonide gel?
Lidex
129
What is the brand name for Dexamethasone Elixir 0.5mg/5ml?
Decadron
130
What is the brand name for Clobetasol proprionate 0.05% gel?
Temovate
131
Prescription Form - How to treat lichen planus?
• Treatment: Steroids • Aphthasol 5%, 5 gm tube, apply to ulcer • Betamethasone (Celestone) Syrup, dispense 8 oz., 1 tsp qid, gargle & expectorate. • Temovate .05% ointment, 15 or 30 gm tube • Decadron Elixir 0.5mg/5ml, Rinse & expectorate. • Lidex 0.05% ointment or gel • Medrol Dose pack 1. You can use Aphthasol 5%, 5 gm tube, apply to ulcer 2. (High Potency Topical Corticosteroid) - Fluocinonide 0.05% (Lidex). Dispense 15 gm tube. Apply sparingly to affected areas qid. 3. Dexamethasone Elixir 0.05mg/5ml (Decadron) - Dispense two 100 ml bottles. Rinse with 1 tsp for 3-4 min after meals and at bedtime and spit out 4. (Highest Potency) - Clobetasol Propionate 0.05% Gel (Temovate). Suspense 15 g tube. Have them dry the infected area, gently massage a thin amount two to three times a day. - And if gel is not working, use Prednisone (systemic) 10 mg tablets. Dispense 40 tablets. Sig: 2 tabs bid for 7 days, then 1 tab bid for 4 days, then 1 tab daily til gone.