Midterm Flashcards
properties of protein structure
size
shape
charge
hydrophobic/hydrophillic
prosthetic group
a molecules that is permanently associated with a protein and required for its function
ligand
a molecule that is bound reversibly by a protein
binding site
the region a protein surface that interacts with a ligand
induced fit
structural adaptation b/w protein and ligand
substrates
are ligands that are chemically altered by the protein (enzyme) they bind
catalytic/active site
site on the enzyme where the substrate binds and chemical transformation occurs
myoglobin
monomer binds and stores O2 in muscle
hemaglobin
blood protein binds reversibly to oxygen
- O2 transporter
- tetramer
leghemoglobin
protects bacteria from O2 so it can make N
-found in legumious plants
the subunits of hemoglobin are held together by?
1, hydrophobic interactions
- hydrogen bonds
- ion pairs (salt bridges)
kinase
take some molecule X-OH using ATP as a source of phosphate you make your X a phosphate group
phosphatase
- undoes the work of kinase but doesn’t do the reverse reaction
- cleaves it using water not a reverse reaction b/c you don’t get ATP back
- hydrolyses phosphate groups
phosphorylase
use something other than water to remove a phosphate group
hydrolase
break any sort of ether type bond by using water
