Midterm

Question 1

Well-circumscribed, corticated, notched RL lesion below mandibular canal at mandibular angle

Answer 1

Stafne defect

Question 2

Doughy, pitting 2cm swelling on anterior midline FOM

Young M = F

Slow growing, elevates tongue

Answer 2

Dermoid cyst

Question 3

Etiology of squamous papilloma

Answer 3

Papovavirus

HPV 6, 11

Question 4

Etiology of verruca vulgaris

Answer 4

Papovavirus

HPV 2, 4, 6, 40

Question 5

Etiology of condyloma acuminatum

Answer 5

HPV 16, 18

Question 6

Etiology of molluscum contagiosum

Answer 6

MCV Poxvirus

Question 7

Anatomic sites of preference BCC/SS/Melanoma

Answer 7

BCC/SCC: Sun exposed or traumatized skin.

SCC: Lip/pinna
BCC: Never oral
Melanoma: BANS, females (lower limbs, calf), males (trunk, H&N, intrascapular)

Question 8

Head and neck prognostic factors

Answer 8

3% of cancers
Decreasing incidence
50% survival/5 years
SCC 90%, M > F
T = local tumor growth
N = LN
M = metastasis

Question 9

Head and neck staging

Answer 9

Stage 1: T1NOMO 85% <2cm
Stage 2: T2NOMO 66% 2-4cm
Stage 3: T1-T3, N1MO 41%, >4cm
Stage 4: T4,N2-3,M1 9%, bone and MF spaces invaded

Question 10

Oral hairy leukoplakia etiology

Answer 10

EBV related lesion in patients w/ HIV/AIDS, candidiasis

Question 11

White lesion on lateral border of tongue, doesn’t rub off, thickened

“Balloon cells”, parakeratin hyperplastic epithelium. Nuclear beading

Answer 11

Oral hairy leukoplakia

Question 12

Most common malignant neoplasm

Answer 12

Sinonasal SCC

Question 13

Vascular and fibrous neoplasm
Adolescent males due to hormonal influence
Epitaxis, nasal airway obstruction
Locally aggressive destruction
TX: Resection, embolization

Answer 13

Juvenile nasopharyngeal angiofibroma

Question 14

Primitive neuroectodermal tumor
Small round blue cell tumor
Rapidly growing, ulcerated tumor
Radiographically destructive, poorly defined, “onion skin” periosteal reaction

Answer 14

Ewings sarcoma

Question 15

Well circumscribed, unilocular, bowing of inferior cortex
Benign mesenchymal neoplasm
Adult female
Mandible PM/M

Answer 15

Ossifying fibroma

Question 16

Asymptomatic pseudocyst w/ salivary parenchyma

Answer 16

Stafne defect

Question 17

Most common form of orofacial clefting

Sex difference?

Answer 17

Cleft lip nad palate 45%

M>F

Question 18

Most common form of syndromic clefting

Answer 18

van der Woude syndrome

Question 19

Diffuse, milky gray, folded edematous mucosa on BM in black adults/smokers

Stretching removes appearance, doesn’t rub off

Answer 19

Leukoedema

Question 20

Cleft lip pathogenesis

Seen where?

Answer 20

Failure of fusion of median nasal process + medial brachial arch of maxillary process

Maxillary laterals and canines

Question 21

Embryologic fissural cyst

NLD remnant

Answer 21

Nasolabial cyst

Question 22

NLC characteristics

Answer 22

Extraosseous
Unilateral 90% soft tissue cyst in upper lip
Can cause nasal obstruction/pain

Question 23

Cystic teratoma of entrapped embryonic germinal epithelium

HX: Keratin/hair/glands/skin

Answer 23

Dermoid cyst

Question 24

Reactive epithelial hyperplasia to epithelial damage in mucosa/gingiva/skin/genitals

Answer 24

Verruciform xanthoma

Question 25

Verruciform xanthoma etiology

Answer 25

HPV? No association to metabolic disorders Assoc. w/ LP/lupus/PV/SCC/GVHD/CHILD

Question 26

Warning signs for melanoma

Answer 26

``` New pigmented lesion Enlargement of mole Color change mole Itching mole Bleeding, painful mole ```

Question 27

Prognostic signs for melanoma

Answer 27

``` Thickness Ulceration Location - extremities better prognosis than H&N Clark level (depth) from 1-5 Treatment time 100% cure rate early ```

Question 28

ABCDs of lesions

Answer 28

``` Asymmetry Border irregularity Color variation Diameter >6mm Expansion/enlargement ```

Question 29

H&N cancer pattern of metastasis

Answer 29

Invasive: Non-healing ulcer, indurated, fixated, submucosal neck mass Distant: Lung>liver>skin>bone>brain 10-40% field cancerization

Question 30

Syphilis stages

Answer 30

1- Chancre: rubber button w/ ulcerated borders at anus 2-Condyloma lata: Maculopapular wart like cutaneous rash in palm or soles 3-Latent, gumma: Interstitial luetic glossitis tongue is premalignant

Question 31

Common in uncontrolled insulin-dependent diabetics and those who are ketoacidotic Nasal obstruction/bloody nasal discharge/facial pain Intraoral swelling of maxillary alveolar process

Answer 31

Mucormycosis

Question 32

Well circumscribed, unilocular, bowing of inferior cortex Mandible PM/M

Answer 32

Ossifying fibroma

Question 33

Familial adenomatous polyposis syndrome - APC gene ``` Intestinal polyps Osteomas Epidermal cysts Thyroid cancer or carcinoma Supernumerary teeth ```

Answer 33

Gardner syndrome

Question 34

#1 inherited bone disease due to type 1 collagen mutation Osteopenia, bone fractures, blue sclera, opalescent teeth, joint hypermobility, hypoacusis, wormian bones

Answer 34

Osteogenesis imperfecta

Question 35

Greatest malignant potential, most common SN papilloma

Answer 35

Inverted papilloma

Question 36

Inverted papilloma characteristics

Answer 36

Lateral nasal wall/paranasal sinuses | <7% HPV 6/11/16

Question 37

Painless oral vesicles that rupture

Answer 37

Herpes zoster

Question 38

Herpes zoster info

Answer 38

HHV-3 is primary infection (varicella) Latent in DRG. Secondary prodrome in skin/eyes with intense pain