Midterm Medications

Question 1

Indications of Sertraline (Zoloft)

Answer 1

MDD 
OCD
Panic disorder 
PTSD
PMDD 
social anxiety disorder

Question 2

Action of SSRI

Answer 2

inhibit uptake of serotonin in the CNS

Question 3

SSRIs

Answer 3

sertaline (zoloft)

fluoxetine (prozac)

Question 4

common side effects

Answer 4

Headache
Nausea
Insomnia/anxiety
Weight gain/loss
Sexual dysfunction
Serotonin syndrome: serious, life threatening

Question 5

contraindications of SSRIs

Answer 5

hypersensitivity
concomitant use of SSRIs with or within 14 days of MAO inhibitors
concomitant use of SSRIs with pimozide

Question 6

serotonin syndrome

Answer 6

Most often a drug drug interaction
Symptoms: diarrhea, restlessness, agitation, hyperreflexia, autonomic instability, myoclonus, seizures, delirium, coma, status epilepticus, cardiovascular collapse
Treatment: Removal of agent, medications to block serotonin receptors
Supportive nursing care

Question 7

indications of Fluoxetine (Prozac)

Answer 7

depression 
depressive episodes associated with bipolar 1 disorder and treatment resistant depression 
OCD 
bulimia nervousa
panic disorder 
PMDD

Question 8

antipsychotics

Answer 8

haloperidol 
clozapine 
risperidone 
quetiapine
olanzapine 
aripiprazole

Question 9

haloperidol

Answer 9

haldol

Question 10

clozapine

Answer 10

clozaril

Question 11

risperidone

Answer 11

risperdal

Question 12

quetiapine

Answer 12

seroquel

Question 13

olanzapine

Answer 13

zyprexa

Question 14

aripiprazole

Answer 14

abilify

Question 15

haloperidol indications

Answer 15

psychotic disorders
tourettes disorder
pediatric behavior problems and hyperactivity

Question 16

action of haldol

Answer 16

blocks postsynaptic dopamine receptors in the hypothalamus, limbic system, and reticular formation

Question 17

contraindications of haldol

Answer 17

hypersentivity

co-administration with other drugs that effect the QT wave

Question 18

side effects of FGA

Answer 18

EPS:  Extra Pyramidal Side Effects
Cogwheeling
Dystonia
Akathesia
Tardive dyskinesia (TD)
Parkinsonianism

Neuroleptic Malignant Syndrome (NMS): potentially life threatening

Orthostatic hypotension

Question 19

FGA

Answer 19

Haldol (Haloperidol)

Question 20

Clozapine (clozaril) indications

Answer 20

treatment resistant schizo

recurrent suicidal behavior

Question 21

side effects of clozapine

Answer 21

low EPS
risk for agranulocytosis and myocarditis
assess for infection
monitor WBC closely-> weekly 1st 6 months and monthly thereafter for maintenance
slow titration up to 300 mg/QD

Question 22

side effects of SGA

Answer 22

weight gain
dyslipidemia
T2DM
Accelerated CVD
Metabolic syndrome

Question 23

metabolic syndrome with SGA

Answer 23

WHEN PT HAS 3+ of the following: 
abdominal obesity
hight triglyceride
HTN
low HDL
elevated blood glucose level

Question 24

clozapine contraindications

Answer 24

hypersensitivity
myeloproliferative disorders
hx of clozapine induced agranulocytosis 
using other drugs that potentially depress bone marrow function
suppressed CNS

Question 25

indications of quetiapine (seroquel)

Answer 25

schizophrenia acute manic episodes MDD OCD

Question 26

quetiapine (seroquel) mechanism of action

Answer 26

through combo of dopamine and serotonin receptor antagonism

Question 27

Risperidone (Risperdal) indications

Answer 27

bipolar mania schizophrenia irritability associated with autistic disorder

Question 28

quetiapine (seroquel) contraindications

Answer 28

hypersensitivity drugs that prolong QT wave hx of arrhythmias including bradycardia

Question 29

Risperidone (Risperdal) contraindications

Answer 29

comatose or severely depressed hypersensitivity bradycardia, recent MI, uncompensated HF hx of prolonged QT or arrhythmias

Question 30

Olanzapine (Zyprexa) indications

Answer 30

schizophrenia bipolar disorder acute agitation associated with schizo and mania

Question 31

Aripiprazole (Abilify) indications

Answer 31

bipolar mania schizophrenia irritably associated with autistic disorder MDD adjunctive tx

Question 32

Aripiprazole (Abilify) contraindications

Answer 32

hypersensitivity | lactation

Question 33

FGA antipsychotics

Answer 33

haloperidol

Question 34

SGA antipsychotics

Answer 34

``` Clozapine (Clozaril) Risperidone (Risperdal) Quetiapine (Seroquel)in Olanzapine (Zyprexa) Aripiprazole (Abilify) ```

Question 35

Benztropine (cogentin) indications

Answer 35

parkinsonism | drug induced EPS

Question 36

Amantadine (symmetrel) indications

Answer 36

parkinsonism | drug induced EPS

Question 37

Amantadine (symmetrel)

Answer 37

increases dopamine at the receptor

Question 38

Benztropine (cogentin)

Answer 38

blocks acetylcholine receptors to diminish excess cholinergic effects

Question 39

Stimulants

Answer 39

Methylphenidate (Ritalin, Concerta) Dextroamphetamine/amphetamine (Adderall) Lisdexamfetamine (Vyvanse)

Question 40

Amphetamine/ dextroamphetamine (adderall) indications

Answer 40

ADHD | Narcolepsy

Question 41

Amphetamine/ dextroamphetamine (adderall) lisdexamfetamine (vyvanse) contraindications

Answer 41

Advanced arteriosclerosis Symptomatic CVD Moderate to severe htn Hyperthyroidism

Question 42

Amphetamine/ dextroamphetamine (adderall) lisdexamfetamine (vyvanse) side effects

Answer 42

``` Overstimulation Restlessness Dizziness Insomnia Headache Palpations Tachycardia Elevated BP Tolerance ```

Question 43

Amphetamine/ dextroamphetamine (adderall) and lisdexamfetamine (vyvanse) mechanism of action

Answer 43

CNS stimulation through release of norepinephrine

Question 44

Methylphenidate (Ritalin) indications

Answer 44

ADHD | Narcolepsy

Question 45

Methylphenidate (Ritalin) contraindications

Answer 45

Hypersensitivity Pregnancy/ lactation Clients with anxiety, tension, or agitation Hyperthyroidism Glaucoma Motor tics, Tourette's syndrome, or family he

Question 46

Side effects of Methylphenidate (Ritalin)

Answer 46

``` Headache Nausea Rhinitis Fever Anorexia Insomnia Tachycardia, palpations, HTN GI pain ```

Question 47

lisdexamfetamine (vyvanse) indications

Answer 47

ADHD