misc Flashcards
(14 cards)
phagocytic cells
macrophages, monocytes, neutrophils
what is the MOST important mechanism for B and T cell repertoire diversity at birth?
germ-line gene rearrangement involves very imprecise joining of the V, D, J gene segments
congenial meaning
all genes but one are identical
what is the primary reason for allergy development
abnormal production of IgE antibodies in response to first allergen encounter
how do fatty acids enter the cell
via passive diffusion, as they are lipid soluble
how does oxygen enter the cell
voa passive diffusion, as it is small and non polar
how are peripheral membrane proteins removed from the membrane
easily, by breaking bonds
increased lipid fluidity causes an increase or decrease in diffusion rate
increase
in what cells/areas are there both apical and basolateral membranes for glucose transport and why
in epithelial cells, namely kidney and small intestine, as they are polarised by tight junctions/have distinct membrane domains.
effect of an isosmotic urea solution on a cell
as urea is membrane permeable and there is not usually any inside the cell, it will flow into the cell with its concentration gradient, causing increase in cell osmolarity, thus cell swelling and lysis
what is the H+/K+ ATPase
what does CR1 bind primarily
C3b opsonin
what is MD2
a lipid-binding protein that helps TLR4 bind LPS at the lipid-A portion
what is the NKCC symporter
