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Dispensing Final 2013 > Misc Section Final > Flashcards

Misc Section Final Flashcards

1
Q

Acne agents 2 Trades?

A

Differin

Duac

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2
Q

Differin generic and details?

A

adapalene (acne agent)
• qday
• Cream, lotion, gel
• Reduces comedo formation; acne may worsen the first few weeks due to exacerbation of deep, unseen lesions

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3
Q

Duac generic and details?

A

benzoyl peroxide, clindamycin (acne agent)
• qday
• Gel
• Refrigerate in the pharmacy; can be stored at room temperature for 60 days

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4
Q

Anticoagulant indications and definitions?

A

Indicated for thrombosis; do not dissolve thrombi just keep them from getting bigger
• Thrombosis – presence of a thrombus
• Thrombus – clot

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5
Q

Anticoagulant Trades?

A

Coumadin
Pradaxa
(Mephyton)

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6
Q

Coumadin generic, strengths, MOA

A

warfarin (anticoagulant)
• qday
• 1, 2, 2.5, 3, 4, 5, 6, 7.5, 10 mg tablet
• Inhibits the synthesis of the Vitamin K dependent clotting factors II, VII, IX, and X
• Do not change diet; increasing Vitamin K intake could decrease Coumadin effectiveness

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7
Q

warfarin monitoring details?

A
  • International Normalized Ratio is used to monitor warfarin therapy
  • Patient not taking warfarin → INR of 1 is normal
  • Patient taking warfarin → INR of 2-3 is normal: more than 3 → decrease dose; less than 2 → increase dose
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8
Q

Trade and generic for warfarin overdose?

A

Mephyton - phytonadione

Vitamin K tablets for Coumadin overdose

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9
Q

Pradaxa generic, dosing, MOA

A

dabigatran
• BID
• Thrombin inhibitor; thrombin is an enzyme used for fibrin formation and fibrin is necessary for clot formation
• Does not require monitoring

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10
Q

HMG-CoA Reductase Inhibitor MOA, counseling, dosing

A

Inhibit enzyme preventing the conversion of HMG-CoA to mevalonate (decrease cholesterol)
o May cause rhabdomyolysis – muscle pain and weakness
• Muscle tissue is destroyed → myoglobin is released → may precipitate in the kidney → renal failure
o Administer in the evening because cholesterol is synthesized mainly at night
o All qday (Exception: Lescol BID)

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11
Q

HMG-CoA Reductase Inhibitor generics?

A 
fluvastatin
pravastatin
simvastatin
atorvastatin
rosuvastatin
pitavastatin
lovastatin
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12
Q

fluvastatin Trade?

A

Lescol, Lescol XL

HMG-CoA Reductase Inhibitor

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13
Q

pravastatin Trade?

A

Pravachol

HMG-CoA Reductase Inhibitor

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14
Q

simvastatin Trade?

A

Zocor

HMG-CoA Reductase Inhibitor

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15
Q

atorvastatin Trade?

A

Lipitor

HMG-CoA Reductase Inhibitor

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16
Q

rosuvastatin Trade?

A

Crestor

HMG-CoA Reductase Inhibitor

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17
Q

pitavastatin Trade?

A

Livalo

HMG-CoA Reductase Inhibitor

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18
Q

lovastatin Trade?

A

Mevacor and Altoprev

HMG-CoA Reductase Inhibitor

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19
Q

Bile Acid Sequestrants dose form and counseling?

A

o Powder for oral suspension → mix with 8 ounces water and drink
o HMG-CoA reductase inhibitors and bile acid sequstrants should not be administered concurrently → reduced bioavailability of HMG-CoA reductase inhibitors

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20
Q

Bile Acid Sequestrants generics?

A

cholestyramine
colestipol
colesevelam

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21
Q

cholestyramine Trade?

A

Questran, Prevalite

Bile Acid Sequestrants

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22
Q

colestipol Trade?

A

Colestid

Bile Acid Sequestrants

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23
Q

colesevelam Trade and details?

A 
Welchol (Bile Acid Sequestrant)
•625 mg tablet: 6 tablets qdaily or 3 tablets BID
•1.875 g packet for oral suspension: BID
•3.75 g packet for oral suspension: qday
•3.75 g daily dose
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24
Q

Miscellaneous Cholesterol drug generics? (5)

A

ezetimibe, exetimibe + simvastatin,
omega 3-fatty acids, gemfibrozil
fenofibrate, fenofibric acid

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25
ezetimibe Trade and MOA?
Zetia | inhibits cholesterol absorption in the small intestine
26
ezetimibe combination product?
Vytorin | ezetimibe, simvastatin
27
omega 3-fatty acids Trade and dosing?
Lovaza •1000 mg capsule •4 grams qday; single dose or 2 capsules BID
28
fenofibrate Trade?
Tricor, Triglide, Lofibra
29
fenofibric acid Trade and extra?
Trilipix | •May be used concomitantly with an HMG-CoA reductase inhibitor
30
gemfibrozil Trade and dosing?
Lopid | BID
31
Antimigraine agents generics? | Super Elephants Feel nauseated zooming along rollercoasters)
``` sumatriptan eletriptan frovatriptan naratriptan zolmitriptan almotriptan rizatriptan ```
32
sumatriptan Trade and dosing?
Imitrex • Tablets: 25 mg, 50 mg, 100 mg → max daily dose of 200 mg • Injection: 4 mg/0.5 mL, 6 mg/0.5 mL • Nasal spray: 20 mg
33
eletriptan Trade and dosing?
Relpax | •20 mg & 40 mg tablet→ max daily dose of 80 mg
34
frovatriptan, naratriptan Trades?
Frova - frovatriptan | Amerge - naratriptan
35
zolmitriptan, almotriptan Trades?
Zomig - zolmitriptan | Axert - almotriptan
36
rizatriptan Trade and dosing?
``` Maxalt (5mg, 10mg tablet → max daily dose of 30 mg) Maxalt MLT (5mg, 10mg OTD) ```
37
Daily vit D and calcium needs for age groups?
* Patients under 70 need 600 units/day of vitamin D * Patients over 70 need 800 units/day of vitamin D * Women under 50 and men under 70 need 1,000 mg/day of calcium * Women over 50 and men over 70 need 1,200 mg/day of calcium
38
Osteoporosis medication counsing?
o Take on an empty stomach, take with a full glass of water, and remain upright for 30 minutes • Can cause esophageal irritation
39
Osteoporosis generics?
risedronate, ibandronate, alendronate alendronate/cholecalciferol calcitonin-salmon teriparatide
40
risedronate Trade and dosing?
Actonel (bisphosphonate) • qweekly – 35 mg tablet • qmonthly – 70 mg tablet
41
ibandronate Trade and dosing?
Boniva (bisphosphonate) • qmonthly • 150 mg tablet
42
alendronate Trade and dosing?
Fosamax (bisphosphonate) • Qweekly • 70 mg tablet
43
alendronate combination product Trade and dosing?
Fosamax Plus D (cholecalciferol) • Qweekly • Tablet • 4 tablets/pack • 70 mg alendronate, 70 mcg cholecalciferol (2,800 units of Vitamin D) • 70 mg alendronate, 140 mcg cholecalciferol ( 5,600 units of Vitamin D)
44
calcitonin-salmon Trade and dosing, storage?
Miacalcin, Fortical • One spray qday, Nasal spray • Refrigerate in the pharmacy; can be stored at room temperature for 30 days • Cannot be substituted for one another
45
teriparatide Trade and dosing?
Forteo •qday SQ injection •Stimulates osteoblast production and bone formation •Refrigerate
46
Proton Pump Inhibitor indications, MOA?
o Indicated for treatment of duodenal ulcers, GERD, gastric ulcers, and Zollinger-Ellison syndrome o Block the final step of gastric acid production by inhibiting the proton pump in the gastric mucosa o Acid-labile medications o Administered qday
47
PPI generics? | L_, O_, PRO
``` lansoprazole dexlansoprazole omeprazole esomeprazole pantoprazole rabeprazole omeprazole, sodium bicarbonate ```
48
lansoprazole Trade and dosing?
Prevacid - 15mg, 30mg Delayed release capsule; 15mg is OTC | Prevacid Solutab - 15mg, 30mg ODT (enteric coated microgranules)
49
dexlansoprazole Trade and dosing?
Dexilant - R-isomer | dual release mechanism: initial release, 2nd release 4 hours later
50
omeprazole Trade and dosing? | esomeprazole Trade?
Prilosec (omeprazole) • 10, 20, 40 mg delayed release capsule • 20 mg delayed release tablet Nexium (esomeprazole)
51
pantoprazole, rabeprazole Trades?
Protonix (pantoprazole) | Aciphex (rabeprazole)
52
omeprazole combination product Trade and details?
Zegerid, Zegerid OTC omeprazole, sodium bicarbonate • Capsule • Single packets of powder for oral suspension → mix with 30 mL of water before using • Sodium bicarbonate protects omeprazole from gastric acid
53
Histamine-2 receptor antagonist MOA and Indications?
o Inhibit gastric acid secretion by inhibiting the action of histamine at the H-2 receptors on the parietal cells o Indicated for duodenal ulcers, gastric ulcers, heartburn, and GERD
54
H-2 receptor antagonist generic/Trade and dosing?
Zantac - ranitidine • 75, 150, 300 mg tablet: 75 and 150 mg are available OTC • 15 mg/mL syrup
55
Indication and generics for antihcolinergic?
Ind: overactive bladder trospium darfenacin solifenacin
56
trospium Trade and form?
Sanctura - IR tab Sanctura XR - ER capsule anticholinergic
57
darifenacin, solifenacin Trade and dosing?
Enablex darifenacin qday | Vesicare solifenacin qday
58
Phosphodiesterase Inhibitors generics?
sildenafil - Viagra vardenafil - Levitra tadalafil - Cialis
59
sildenafil Trade and strengths, counseling
Viagra • 25 mg, 50 mg, 100 mg tablet • Take on empty stomach one hour before sexual activity • Seek medical assistance if priapism lasts more than 4 hours • No effect if there is no sexual stimulation
60
vardenafil Trade and strength, counseling?
Levitra • qday • 2.5 mg, 5 mg, 10 mg, 20 mg tablet • Take on empty stomach
61
tadalafil Trade and strength, indications
``` Cialis • qday • 2.5 mg, 5 mg, 10 mg, 20 mg tablet • Treatment of BPH symptoms and impotence • Can be taken without regard to meals ```
62
Alzheimer's drug category, MOA?
o Cholinesterase inhibitors: inhibit cholinesterase → increase ACh levels in the brain o NMDA receptor antagonist: block actions of glutamate by binding to NMDA receptors
63
cholinesterase inhibitor generics?
rivastigmine - Exelon Patch donepezil - Aricept galantamine - Razadyne memantine - Namenda (XR)
64
rivastigmine, galantamine Trades?
Exelon Patch - rivastigmine | Razadyne - galantamine
65
donepezil Trade and strengths?
``` Aricept • qday • 5 mg, 10 mg, 23 mg tablet • 5 mg and 10 mg ODT • Patients can increase dose to 23 mg if taking 10 mg for three months ```
66
memantine Trade and strengths?
``` Nemenda - BID 5mg, 10mg tab; oral solution Namenda XR - QDay , 14, 21, and 28 mg ER capsule • Initial dose: 7 mg qday → increase in weekly 7 mg increments • Maintenance dose: 28 mg qday ```
67
5 alpha reductase inhibitors MOA and trades?
Metabolizes testosterone to dihydrotestosterone → alopecia and prostate enlargement finasteride dutasteride
68
finasteride Trades and dosing?
Proscar (5mg qday for prostate reduction) Propecia (1mg qday for alopecia) must use for 3 months to see results and withdrawal of treatment leads to reversal of effect within 12 months
69
dutasteride Trade and indication?
Avodart | Benign prostatic hyperplasia
70
Skeletal Muscle Relaxants (4) | sick zebras feel sad
Skelaxin metaxolone Zanaflex tizanidine Flexeril cyclobenzaprine Soma carisoprodol
71
Bowel disease suppressant indication and generic?
mesalamine | for ulcerative colitis
72
Trades for mesalamine and dosing? | 6
``` Delzicol - TID 400mg DR cap Asacol HD - TID 800mg DR tab Lialda - QDay 1.2g tab Pentasa - ER capsule Rowasa - rectal suspension Canasa - rectal suppository ```
73
topical immunosuppressant?
Elidel - pimecrolimus Ind: atopic dermatitis BID cream
74
local anesthetic?
Lidoderm - lidocaine • qday Transdermal • Indicated for pain associated PHN • Put one on for 12 hours, then remove for 12 hours
75
osmotic laxative for constipation directions and generic/Trade?
polyethylene glycol 3350 MiraLax - OTC GlycoLax - Rx Powder for oral solution: 17 g of powder in 8 ounces of water
76
bowel cleansing laxatives directions?
* Powder for oral solution: drink 8 ounces of solution every 10 minutes until 4 L are consumed * Exception: HalfLytely is a 2 L solution * Contain electrolytes to replace those lost during the bowel cleansing
77
bowel cleansing laxatives Trades?
``` polyethylene glycol 3350 TriLyte MovePrep CoLyte Nulytely HalfLytely ```
78
gastrointestinal agent Trade/generic and indications?
Amitiza - lubiprostone BID •8 mcg capsule for IBS •24 mcg capsule for chronic constipation
79
smoking cessation Trade generic and dosing?
``` Chantix - varenicline • 0.5 mg and 1 mg tablet • Day 1-3: 0.5 mg qday • Day 4-7: 0.5 mg BID • Day 8 through end of treatment: 1 mg BID ```
80
antineoplastic agents other name, indications, counseling?
Aromatase Inhibitors Ind: breast cancer Tx o Causes an increased risk of fractures due to reduction in bone mineral density → use a bisphosphonate or calcium supplement
81
Aromatase Inhibitor Trade/generics
Arimidex anastrozole | Femara letrozole
82
Immunosupressant agents indications and Trade/generic?
Ind: prophylaxis of organ rejection mycophenolate - CellCept, Sandimmune (BID) cyclosporine - Neoral
83
topical anticholinergic?
Transderm-Scop - scopolamine oInd: prevention of nausea and vomiting: apply 4 hours before antiemetic effect is needed oApply every 3 days
84
Last 4 Random shit generics?
metoclopramide allopurinol febuxostat clonidine
85
metoclopramide strengths, Ind, category?
* 5 mg and 10 mg tablet * 5 mg/5 mL syrup * Indicated for GERD * Gastrointestinal stimulant * For children the dose is often less than 1 mL: overdose causes extrapyramidal effects
86
allopurinol Trade and Ind, category?
Zyloprim Ind: gout Xanthine oxidase inhibitor
87
febuxostat Trade and dosing, Ind, category?
Uloric - QDay Ind: gout Xanthine oxidase inhibitor
88
clonidine oral Trade and dosing?
``` Catapres • qday • 0.1, 0.2, 0.3 mg tablet • Antihypertensive • Do not discontinue abruptly → rebound hypertension ```
89
clonidine transdermal Trade and dosing?
``` Catapres TTS • qweek • 0.1, 0.2, 0.3 mg/24 hours transdermal • Antihypertensive • Do not discontinue abruptly → rebound hypertension ```

Dispensing Final 2013 (3 decks)

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