Misc. Terminology Flashcards
1
Q
Cytokines
A
Proteins that will alter the response of the immune system
2
Q
Interferons
A
Antiviral activity, tumoricidal effects. Stimulate macrophages, T cells, B cells, and NK cells.
3
Q
Alpha and B interferons
A
- Type 1
- Synthesized by macrophages, fibroblasts, and other cell types (T cells?)
4
Q
Gamma interferon
A
- Produced by T cells that are stimulated.
- Stimulates macrophages
- Leads to differentiation of T cells and B cells
5
Q
IL-1
A
- Made primarily by macrophages
- Stimulates T, B liver, bone, synovial, brain, and muscle cells
6
Q
IL-2
A
- Produced by T cells
- T cell growth factor (formerly known as)
- Stimulates B cells and macrophages
7
Q
IL-3
A
- Colony stimulating factor (CSF)
- Production of many different types of cells
8
Q
IL-4
A
- B cell growth factor
- Important in T-cell stimulation of B-lymphocytes
- T cell growth factor
- Regulator of T cell function
9
Q
IL-5
A
- B cell growth factor and differentiation factor
- Eosinophil growth factor
10
Q
IL-6
A
-Principal mediator of the acute phase response of inflammation
11
Q
IL-10
A
-Stimulates induction of TH-2 cytokines and may suppress TH1 cytokines
12
Q
IL-12
A
-Stimulates TH1 response
13
Q
IL-17
A
-Involved in inflammation
14
Q
CSF-1
A
-Macrophage colony formation
15
Q
GM-CSF
A
-Granulocyte and macrophage colonies
