Miscellaneous Flashcards

(72 cards)

1
Q

The transfer of the drug from the body fluids to the tissues

A

Absorption

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2
Q

Water soluble drugs have what kind of absorption?

A

Passive absorption

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3
Q

When does drug bioavailability occur?

A

After it’s metabolized

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4
Q

What increases half-life in patients, which can increase toxicity?

A

Kidney, liver disease, and old age

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5
Q

What neutralizes the effects of heparin?

A

Protamine sulfate

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6
Q

How long before meals should PPI’s be taken?

A

1 hour

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7
Q

How much analgesic properties do benzodiazepines have?

A

NONE

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8
Q

How long should patients lie down after taking benzo’s?

A

30 minutes

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9
Q

Increase levels of norepinephrine and serotonin by inhibiting their reuptake and block the action of acetylcholine

A

TCA’s

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9
Q

Increase levels of norepinephrine and serotonin by inhibiting their reuptake and block the action of acetylcholine

A

TCA’s

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10
Q

Increase serotonin by inhibiting neuronal uptake to CNS

A

SSRI

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11
Q

Trazodone is what class of antidepressant?

A

Serotonin Reuptake inhibitor/antagonist

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12
Q

May experience an aura with perceptual alterations and hallucinations

A

Psychomotor Seizure

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13
Q

Alternate contraction and relaxation of muscles

A

Tonic-clonic

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14
Q

Sudden, forceful contraction involving the musculature of the trunk, neck, extremities

A

Myoclonic seizures

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15
Q

What is used to treat patients with generalized convulsive status epilepticus (GCSE)?

A

Benzodiapines

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16
Q

What is classified as GCSE?

A

5 minutes or more of continuous seizure activity or more than 1 seizure without recovery in-between

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17
Q

What acts on the chemoreceptor trigger zone to inhibit nausea and vomiting?

A

Penothiazines

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18
Q

What decreases nausea and vomiting by its effects on gastric emptying?

A

Metoclopramide

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19
Q

What blocks effects of serotonin at 5-HT3 receptor sites?

A

Ondansetron

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20
Q

Use phenothiazines in children when you suspect what?

A

They have a viral disease

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21
Q

What causes Reye Syndrome in children with chickenpox or influenza?

A

Asprin

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22
Q

Naloxone releases what?

A

Catecholamines

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23
Q

Releases stimulants and reuptake inhibitors that increase the levels of endogenous catecholamines

A

Beta2 Agonists

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24
Antagonizes acetylcholine receptors, producing bronchodilation
Muscarinic Antagonists
25
Antitussive Central Acting =
Depresses cough center
26
Antitussive peripheral acting =
Anesthizes stretch receptors
27
What antiarrhythmic class is used for ventricular dysrhythmias and Atrial fibrillation?
Class 3
28
Direct relaxing effect on smooth muscle of blood vessels
Nitrates
29
HTN Management Step 2
Use a thiazide diuretic, ACE-I, ARB, CCB
30
HTN Management Step 3:
Increase dose of drugs or combine 2 drugs
31
HTN Management step 4
Combine 2-3 drugs, Increase the dose
32
Stimulates the secretion of aldosterone by the adrenal cortex on the kidney
ACE Inhibitors
33
Causes peripheral vasodilation
CCBs
34
Can cause hypotension, bradycardia, and bronchospasm
Beta Blockers
35
Inhibit reabsorption of sodium and chloride ions in the kidney
Thiazide diuretic
36
Reduces VLDL and stimulates the catabolism of triglyceride-rich lipoproteins
Fenofibrate
37
Antacid that can cause severe diarrhea, dehydration, and hypermagnesemia
Magnesium containing
38
Antacid that can cause rebound hyperacidity and metabolic alkalosis
Calcium containing
39
Stimulates peripheral glucose uptake and stimulates the synthesis of glycogen by the liver
Insulin
40
Lowers blood glucose by stimulating beta cells of the pancreas to make more insulin
Sulfonylureas
41
Reduces hepatic glucose production and increases insulin sensitivity in muscle and fat cells
Biguanides
42
Stimulates the release of insulin
Meglitinides
43
Decreases insulin resistance and increases insulin sensitivity
Thiazolidinediones
44
Influences every organ and tissue in the body
Thyroid hormones
45
Active against bacteria
Antibacterial
46
Not used near end of pregnancy or significant blood levels can occur. Use with caution in patients with bronchial asthma
Sulfonamides
47
H. Ployri treatment
Clarithromycin, amoxicillin and a PPI
48
Treat lower respiratory infections (acute exacerbation of chronic bronchitis), Acute Pyelonephritis, Diverticulitis, Atypical pneumonia
Fluoroquinolones
49
Because of severe effects, reserve fluoroquinolones for patients who have no other options for:
Uncomplicated UTI's, Chronic bronchitis, and acute bacterial Sinusitis
50
Exert their bactericidal effect by blocking a step in protein synthesis necessary for multiplication, disrupt the functional ability of the cell membrane
Aminoglycosides
51
Bacterial Meningitis treatment
Aminoglycoside with penicillin or ampicillin
52
Complicated UTI Treatment
Aminoglycosides
53
Extended spectrum beta-lactamases (ESBL)
Caarbapenems
54
Enzymes that open the beta-lactam ring, inactivating the antibiotic
Beta-lactamases
55
Treats anaerobic bacterial infections (Clostridium, Bacteroides spp., B. Fragilis), GYN Infections, Antiprotozoal (Giardiasis & Amebiasis)
Amebicide, Antiprotozoal, and Nitroimidazole
56
Amebiases, Giardiasis, Vaginal Trichomoniasis treatment
Tinadazole
57
Changes cell wall surface, decrease adherence of bacteria to host cells
Lincosomide
58
Bite wound, MRSA, Toxic Shock Syndrome treatment
Lincosomide
59
Appears to have an effect on muscle tone, thus reducing muscle spasms
Cyclobenzaprine
60
SLE treatment
Corticosteroids
61
What causes Cushing's Syndrome?
Corticosteroids
62
Prolonged use of Otic preparations may result in what?
Superinfection
63
Aluminum Acetate, Ciprofloxacin, or Cortisporin can treat what?
Otitis Externa
64
Used for Herpes eye infection
Acyclovir
65
Prevention of cyomegalovirus
Ganciclovir
66
Artificial tears, Erythromycin ointment, Ciprofloxacin, Ganciclovir are all what?
Ophthalmic Preparations
67
NRT examples come in what forms?
``` Transdermal patch Gum Inhaler Nasal Spray Lozenges ```
68
What kind of cough are antitussives used for?
Non-productive
69
Who does the Working Stock Custodian notify if there has been any transactions?
Senior CSIB member
70
What do you do if a controlled substance has been lost in transit?
Consignee must submit a sworn statement of the facts with the DEA form 106
71
What may decrease athletic performance due to higher resting heart rate?
Thermogenics