miscellaneous Flashcards

(33 cards)

1
Q

what is the function of iL-1

A

pyrogen
also calld osteoclast actiating fato

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2
Q

function of IL 2 ?

A

stimulates T cells

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3
Q

function of IL 3 ?

A

stimulates bone marrow stem cells
GM-CSF

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4
Q

function of IL 4 ?

A

helps for the differentiation into Th2
stimulates IgE production
maturation of B cells

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5
Q

function of IL 5 ?

A

stimulates IgA production
B cell differentiation
differentiation of eosinophils

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6
Q

function of IL 6 ?

A

stimulates the liver too create acute phase proteins

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7
Q

what is the mnemonic for IL 1 to 6 ?

A

HOT T BONE stEAK

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8
Q

function of IL 8 ?

A

chemotaxis for neutrophils

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9
Q

function of IL 10 ?

A

decrease thee expression of MHC 2 and TH1

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10
Q

what are the cytokines that attenuate the immune response ?

A

TGF beta
L 10
Trgg

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11
Q

function of IL 12 ?

A

diffreentiiation ooff t cells into Th1
activation of NK cells

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12
Q

function of IL 13 ?

A

IgE prroductionn

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13
Q

which cytokines are produced by macrophages ?

A

IL 1
IL 6
IL 8
IL 12
TNF alpha

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14
Q

which cytokines are produced by Th1 ?

A

INF gamma

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15
Q

which cytokines are produced by Th2 ?

A

IL 4 , IL 5, Il 10, IL 13

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16
Q

what are the CD fo B cells ?

A

D 19 , 20 , 21

17
Q

whicch CD is used by EBV to enter B cells ?

18
Q

which CD is expressed by macrophages ?

19
Q

what is the D on hematopoeitic cells ?

20
Q

mnemonic for live attenuated vaccines ?

A

attention teachers please vaccinate young beautiful small infants with MMR regularly
Adenovirus
Typhoid
Polio
Varicella
yellow fever
BCG
smallpox
influenza oral
MMR

21
Q

what type of immune response is associated with live attenuated vaccines ?

A

cell mediated iimmunity.

22
Q

what type of immunity is associated with killed vaccine ?

A

humoral response

23
Q

mnemonic for killed vaccines ?

A

A TRIP could Kill you
Hepatitis A
Typhoid
Rabies
Influenza
Polio

24
Q

What is the means of acquisition for passive immunity?

A

Receiving preformed antibodies.

25
What is the means of acquisition for active immunity?
Exposure to exogenous antigens.
26
How quickly does passive immunity onset?
Rapid.
27
How quickly does active immunity onset?
Slow
28
How long does passive immunity last?
Short span of antibodies (half-life = 3 weeks).
29
How long does active immunity last?
Long-lasting protection (memory).
30
Give examples of passive immunity.
IgA in breast milk, maternal IgG crossing the placenta, antitoxin, humanized monoclonal antibody
31
Give examples of active immunity.
Natural infection, vaccines, toxoid.
32
What is a special note about IVIG in passive immunity?
IVIG and other immune globulin preparations can provide temporary but specific passive immunity to a target pathogen
33
When are combined passive and active immunizations given?
For hepatitis B or rabies exposure.