Miscellaneous

Question 1

Blocks dopamine receptors in the CTZ, increases acetylcholine release, enhancing gastric emptying and intestinal transit, and has antiemetic effects.

Answer 1

Metoclopramide

Question 2

CTZ blockers (Chemoreceptor Trigger Zone)

Located: in the medulla oblongata outside the blood-brain barrier

Function - Triggering Nausea and Vomiting and detection of toxins and drugs

Answer 2

Receptor Mediation: It has dopamine (D2), serotonin (5-HT3), histamine (H1), muscarinic (M1), and opioid receptors, making it a target for antiemetic drugs.