miscellaneous Flashcards

(38 cards)

1
Q

ECG signs of Hyperkalaemia

A
  • loss of P waves
  • widened QRS complexes
  • tented T waves
  • bradycardia
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2
Q

Normal PR interval on ECG?

A

120-200 ms

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3
Q

Normal QRS complex on ECG

A

<120ms

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4
Q

Causes of Chronic Pancreatitis

A
  • EtOH
  • autoimmune
  • Steroids
  • malnutrition
  • hereditary
  • Trauma or obstruction
  • Recurrent acute pancreatitis
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5
Q

History of Chronic Pancreatitis

A
  • severe pain radiating to the back
  • relieved by sitting forward
  • Weight loss
  • Loss of exocrine function –> steatorrhea
  • Loss of endocrine function –> diabetes
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6
Q

Investigations for Chronic Pancreatitis

A
NOT amylase (= acute pancreatitis)
Check exocrine function: faecal elastase
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7
Q

Management of Chronic Pancreatitis

A
  1. Pain - analgesia (NSAIDs, opiates)
  2. Endocrine function - if diabetic give insulin
  3. Exocrine function - creon (enzymes)
  4. Give acid suppression: PPI: omeprazole to stop creon deactivation
  5. Coeliac nerve block
  6. Pregabalin
  7. Low fat diet for steatorrhoea (<20g fat a day)
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8
Q

Complications of Chronic Pancreatitis

A
  • pancreatic pseudocyst
  • splenic vein thrombosis
  • obstruction (may need ERCP)
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9
Q

Prognosis of Chronic Pancreatitis

A

High risk of pancreatic Ca

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10
Q

Causes of low phosphate

A
  • malabsorption: vit D
  • Increased PTH (1° hyperparathyroidism)
  • Insulin: drives phosphate into cells
  • Refeeding syndrome (due to insulin secretion when give food)
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11
Q

What is part of a Liver Screen?

A
Alcohol
Autoimmune: (AMA, ANA, LK;M)
Drugs
Viruses: Hep B, C, A
a-fetoprotein if chronic liver disease
USS to look for obstruction or dilatation 
Metabolic: 
- haemochromatosis (increased ferritin)
- Wilson's: excess copper --> measure caeruloplasmin
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12
Q

Causes of pulmonary hypertension

A
Chronic lung disease:
- COPD
- fibrosis
R heart:
- mitral stenosis 
Congenital heart disease:
- VSD etc. 
HIV --> causes idiopathic pulmonary hypertension
Sarcoid
Connective tissue disease: SLE
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13
Q

Henoch-Schönlein purpura

A

= small vessel vasculitis
Presents with purpura (non-blanching purple papules due to intradermal bleeding)
There may be glomerulonephritis, arthritis, and abdominal pain (+/- intussusception) which may mimic an acute abdomen.

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14
Q

Porphyrias

A

= heterogenous group of rare diseases caused by various errors of haem biosynthesis

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15
Q

Modifiable cardiovascular risk factors

A
Alcohol
Blood pressure
Cholesterol (and lipids)
Diabetes/diet
Exercise
Smoking
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16
Q

Non-modifiable cardiovascular risk factors

A
Age/gender/family history
Myocardial infarction
Rheumatic fever
Claudication
Stroke/TIA
17
Q

Respiratory causes of Clubbing

A
Lung Ca
Mesothelioma
Fibrosing Alveolitis
Bronchiectasis
Cystic Fibrosis
Empyema
18
Q

Causes of COPD

A

Smoking
Environmental pollutants
Alpha-1-AT deficiency
Occupational exposure (coal minors etc.)

19
Q

X-ray findings of Heart failure

A
A - alveolar shadowing (Bat wing)
B - Kerley B lines (interstitial oedema)
C - Cardiomegaly
D - upper lobe diversion
E - pleural effusion
20
Q

3 main drugs indicated in heart failure

A

Beta-blockers
ACE inhibitors
Spironolactone

21
Q

Risk factors for jaundice

A
A - alcohol
B - blood (transfusions, taoos, IVDU, needle stick)
C - coitus 
D - drugs
E - expeditions (travel history)
F - family history
22
Q

What is Courvoisier’s Law?

A

A palpable non-tender gallbladder in the presence of jaundice is unlikely to be caused by gallstones.

23
Q

What are Kayser-Fleischer rings?

A

Caused by Wilson’s disease. Only visible with a slit light.

24
Q

GI systems review

A
Mouth ulcers, dental problems
Difficulty swallowing (dysphagia)
Odynophagia
Nausea & vomiting
Haematemesis
Indigestion
Heartburn
Abdominal pain
CIBH
Change in colour of stools
25
What is normal serum bilirubin?
17 microM
26
What is the bilirubin level of visible jaundice?
approximately 35-40 microM
27
Differentials for abdominal distension?
``` Fat Foetus Fluid Faeces Flatus ```
28
What does faecal calprotectin signify?
First line test for IBD. Neutrophil marker.
29
In what condition does dermatitis herpetiformis occur?
Coeliac.
30
Boas' sign
Sign of pain radiating to back & right scapula. Can be associated with acute cholecystitis or gastric or duodenal disease.
31
What is Murphy's sign and what does it indicate?
Murphy's sign --> place hand under right costal margin and ask Pt to take deep breath in; if Pt experiences pain and takes sharp breath in then positive. It indicates acute cholecystitis.
32
3 conditions that cause Rigors
1. Malaria 2. Ascending cholangitis 3. Pyelonephritis
33
What is a gallstone ileus?
An erosive gallstone causing small bowel obstruction; Inflammation of the gallbladder spreads to duodenum and results in fistula formation. Gallstone can pass through and may lodge in the ileocaecal valve in the terminal ileum & air can pass into the biliary tree.
34
In what condition does pyoderma granulosum occur?
UC
35
What are common infective causes of blood in the stool?
``` C - campylobacter H - haemorrhagic E. coli E - entamoeba histolytica S - salmonella S - shigella Y - Yersinia ```
36
What are the cardinal signs of bowel obstruction?
1. Distension (5 F's) 2. Vomiting 3. Pain, colicky 4. Absolute constipation
37
Causes of Intravascular haemolysis
1. Congenital - G6PD deficiency - Sickle cell disease - Thalassaemia 2. Acquired - Artificial heart valves - ABO group mismatch - DIC - Malaria
38
Causes of Extravascular haemolysis
1. Congenital - Hereditary spherocytosis 2. Acquired - Autoimmune haemolysis