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Miscellaneous Tests Flashcards

(7 cards)

1
Q

What is a normal ejection fraction?

A

50-70%

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2
Q

What is an EF of under 40%?

A

HF or cardiomyopathy

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3
Q

What do positive CD34, TDT, PAX5, and CD10 in a bone marrow biopsy correlate with?

A

immature B-cell lymphoblastic leukemia/lymphoma

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4
Q

What is a positive BCR-ABL significant for?

A

Chronic myelogenous lymphoma (usually); also associated with ALL

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5
Q

Reciprocal translocation that results in BCR-ABL is known as the ________ _________.

A

Philadelphia Chromosome

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6
Q

What kind of anti-neoplastic drug would you want to add to treat leukemia if you have a positive BCR-ABL?

A

Tyrosine kinase inhibitor (TKI) must be added to the treatment regimen

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7
Q

An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it.

A

BCR-ABL translocation (Philadelphia chromosome)

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