mitosis Flashcards

(42 cards)

1
Q

what does a cell have to do before it divides

A

replicate its DNA

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2
Q

what are homologous chromosomes

A

genetic info thats the same but from two different parents

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3
Q

what do non dividing chromosomes look like

A

single chromatids

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4
Q

what is the pinch in a 2 chromatid chromosome

A

centromere

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5
Q

what protein holds two chromatids together

A

kinetochore

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6
Q

what are the 4 steps to DNA replication

A

unwinding
unzipping
building new strands
repackaging

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7
Q

what unzips dna

A

dna helicase

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8
Q

what joins 2 strands of DNA

A

dna ligase

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9
Q

what are the three types of DNA mutation / error

A

insertion
substitution
deletion

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10
Q

what are the 3 phases of interphase

A

G1
S
G2

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11
Q

what happens in G1 (2)

A

growth and metabolism

building of organelles

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12
Q

what happens in the S phase

A

DNA replication

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13
Q

what happens in the G2 phase (3)

A

growth
microtubules are made
contractile ring making

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14
Q

prophase (2)

A

chromatin condenses
spindles form

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15
Q

metaphase

A

chromosomes line up at the metaphase plate

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16
Q

anaphase

A

chromosomes separate and go towards opposite poles

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17
Q

telophase / cytokinesis

A

two cells are formed

18
Q

where do microtubules form from

19
Q

what phase does the nuclear envelope break down

20
Q

what phase do microtubules depolymerize

21
Q

what makes the cleavage furrow

A

actin and myosin

22
Q

what are 3 things that happen before a cell divides

A

enough cytoplasm
stimulated by growth factor
neighboring cells die

23
Q

when do cells stop dividing (2)

A

when theyre snug with their neighbors
growth/ nutrients are withdrawn

24
Q

what is contact inhibition

A

cells stop dividing because they come into contact with other cells

25
what is one bad thing that can happen if cells start dividing or stop dividing when they aren't supposed to
cancer
26
when is the first checkpoint
G1
27
when is the second checkpoint
G2
28
when is the last checkpoint what is it called
mitosis M checkpoint
29
what is cancer
unregulated cell growth
30
what acts like breaks to slow down damaging mutations
tumor suppressors
31
what needs two damaged copies to cause cancer
tumor supressor genes
32
what acts like an accelerator to cause damage
proto-oncogenes
33
what only needs one damaged copy to cause cancer
porto-oncogenes
34
where are tumor suppressor genes found
the nucleus
35
where are port-oncogenes found
cytoplasm
36
what's another name for genes
discrete factors
37
what is genotype
genetic makeup
38
what is phenotype
how genetic makeup is expressed
39
when are alleles separated when are they rejoined
gamete formation fertilization
40
is what Mendel assumed about recessive and dominant traits true about most genes
no
41
polygenetic inheritance
determined from dominant and recessive alleles
42