Mitosis Flashcards
(21 cards)
How does one parent cell gives rise to two genetically identical daughter cells.
Interphase
Mitosis
Cytokinesis
Define genome
A cell’s DNA, its genetic information
A typical human cell DNA length
2m
Sister chromatids are attached by
Cohesins
Shortest phase of cell cycle
Mitotic ( M) phase which includes both mitosis and cytokinesis
Mitosis
Cytokinesis
Distribution of chromosomes into two daughter nuclei
division of cytoplasm,producing two daughter cells.Each daughter cell can start a new cycle.
G1
S
G2
Functions
Metabolic activity and growth [unduplicated chromosomes]
Metabolic activity, growth and DNA synthesis[duplicated chromosomes]
Metabolic activity,growth and preparation for cell division
During three phases of interphase
cell grows by producing proteins and cytoplasmic organelles.
A particular human cell might undergo one cell division in
24 hours
[M phase occupies less than 1 hour but S phase occupy more than 10-12 hours or about the half the cycle]
G2 phase takes usulally
4-6 hours
G1 occupies
5-6 hours
G1 is the most variable in length in different types of the cell True/ False
True
Centrosomes
pair of centrioles
How many chromosomes are in G2 of interphase
ZERO because chromosomes are not yet condensed as individuals.
Prophase
The cromatin fibers becomes more tightly coiled,condensing into discrete chromosomes can be seen in LM.
The nucleoli disappear
Each duplicated chromosome appears as two identical sister chromatids joined at the centromeres.
The mitotic spindle begins to from .[The radial arrays of shorter micro-tubules that extend from the centrosomes are called asters ]
The cetrosomes move away from each other.Lengthening micro tubules.
Prometaphase
The nuclear envelope fragments
The microtubules invades the nuclear area
The chromosomes become even more condensed
A kinetochore,a specialized protein structure has now formed at the centromere of each cromatids. Thus two per chromosome
There are kinetochore microtubules and non-kinetochore microtubules
Metaphase
centrosomes are opp at poles of the cell
Metaphase plat [equidistant plate]
Anaphase
shortest phase of mitosis
cohesin proteins are cleaved. hence each cromatid becomes independent chromosome.
The two new daughter chromosomes begin moving towards oo side of the cell as their kinetochore mictrotubile shortens.
Refer pg no 293