mitosis Flashcards

(45 cards)

1
Q

what is the name for nuclear division

A

mitosis

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2
Q

what is mitosis

A

type of nuclear division that maintains the chromosome number; each new daughter cell contains the same genetic information as the parent cell. theyre also genetically identical to each other

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3
Q

what does each new cell produced from mitosis have

A

an exact copy of the DNA present in the parent cell and the same number of chromosomes

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4
Q

when is mitosis necessary

A

when all the daughter cells have to be identical - during growth, replacement and repair of tissues in multicellular organisms

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5
Q

what is asexual reproduction

A

production of genetically identical offspring from one parent in multicellular organisms

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6
Q

why do prokaryotic cells divide by binary fission

A

they have no nucleus so cannot divide by mitosis

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7
Q

what does mitosis form

A

2 new identical daughter cells from original parent cell

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8
Q

how many chromosomes are there in diploid organisms

A

2 copies of each chromosome - 23 pairs

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9
Q

what is the diploid number

A

46

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10
Q

what must happen before mitosis can occur

A

all of the DNA in the nucleus is replicated during interphase. each DNA molecule (chromosome) is converted into two identical DNA molecules called chromatids

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11
Q

what is a chromosome

A

structures in a cell that contain genetic material, also known as DNA.

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12
Q

when are chromosomes visible

A

during cell division.

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13
Q

what does each chromosome consist of

A

two chromatids joined somewhere along its centromere. genetic information along each chromatid is identical

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14
Q

what does each chromosome replicate to form

A

an identical copy (chromatid)

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15
Q

what is a chromatid

A

one of the two identical halves of a chromosome that has been replicated in preparation for cell division. chromatids of a pair are joined at the centromere

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16
Q

why is it necessary to keep the chromatids together during mitosis

A

so they can be manouevred and segregated equally one into each of the daughter cells

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17
Q

what does DNA combine with during interphase

A

proteins called histones to form a dense complex called chromatin

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18
Q

what are histones

A

The proteins that DNA is packaged with. Histones are small spherical structures which the DNA can wind around to make it more compact in the nucleus.

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19
Q

what is chromatin

A

combination of DNA and histones is referred to as chromatin.

20
Q

what is the job of chromatin

A

to package DNA into a unit capable of fitting within the tight space of a nucleus.

21
Q

what are the four stages of mitosis

A

-prophase
-metaphase
-anaphase
-telophase
—-> they are described separately but is a continuous process

22
Q

how can we identify each phase of mitosis

A

under a microscope

23
Q

how can dividing cells be obtained

A

from growing tips of plants. the root tips can be treated with a chemical to allow cells to be separated. then they are squashed to form a single layer of cells on a microscope slide.

24
Q

how can chromosomes be made more visible

A

stains that bind to DNA are used

25
how much does mitosis make up the cell cycle
5-10%. its considered to be a separate process to cytokinesis
26
what happens before nuclear division begins
the cell carries out all of its normal functions. DNA synthesis and checking are complete
27
what happens in early prophase
chromsomes become more distinct - they coil up - shorten - thicken - take up stain more intensely - centriole divides - nucleolus becomes less prominent
28
what is the nucleolus
An area inside the nucleus of a cell that is made up of RNA and proteins and is where ribosomes are made.
29
what happens in late prophase
- chromosomes become more distinct and seen to consist of two chromatids joined by a centromere - centrioles migrate to opposite poles of the cell - nucleolus continues to shrink and disappears - nuclear envelope disintegrates
30
what happens in metaphase
- each centriole is at a pole - centrioles grow and produce spindle fibres - spindle fibres attach to the centromere of the chromosomes - each centromere is attached to both poles - chromosomes are pulled to the metaphase plate or equator
31
what happens in anaphase
- spindle fibres contract - centromere divideds - chromatids (daughter chromosomes) are pulled to opposite ends of the cell - centromere is pulled first - each half of the cell receives one chromatid from each chromosome
32
what happens in telophase
- chromosomes reach the poles of the spindle - they begin to uncoil - they become less distinct - nuclear envelope starts to form - when they reach the poles of the spindle the chromatids are now daughter chromosomes
33
what happens after mitosis is complete
cytokinesis - the cell splits into two
34
what happens in cytokinesis
the cell divides the daughter cells have the same chromosome number and genetic makeup as each other and the parent cell - DNA replication precedes mitosis
35
how does cytokinesis occur in animal cells
the plasma membrane folds inwards and 'nips in' the cytoplasm the edges of the cell constricts
36
how does cytokinesis occur in plants cells
an end plate forms where the equator of the spindle was and new plasma membrane and cellulose material are laid down on either side of this end plate
37
what is the goal of cytokinesis
to separate the cell into two distinct daughter cells
38
why are the mechanism for cytokinesis different in plants and animals
due to their structural differences
39
how does a cleavage furrow form
- a cleavage furrow is created using a ring of contractile protein - actin and myosin - the cleavage furrow reaches the center - the cells are pinched apart into two separate daughter cells
40
how do cell plates form in plant cells
- vesicles moved to the equator where they fuse to from tubular structures across the equator - tubular structures merge to form two plasma membranes of the two daughter cells. completion of cell division - pectins and other substances are deposited between the two membranes by exocytosis forming the middle lamella. - cellulose is brought to the middle lamella by exocytosis - cell walls are formed adjacent to the equator
41
compare the mechanism, structure , speed and outcome of cytokinesis in plant and animal cells
mechanism animal - cleavage furrow (contractile ring) plant - cell plate formation (vesicle fusion) structure animal - felxible plasma membrane plant - rigid cell wall speed animal - relatively fast and flexible plant - slower and more complex outcome animal - two daughter cells separated by membrane plant - two daughter cells separated by a new cell wall
42
what is the significance of mitosis
all living organisms need to produce genetically identical daughter cells
43
why is mitosis needed for asexual reproduction
single celled protoctists such as Amoeba and Paramecium divide by mitosis to produce new individuals some plants e.g. strawberry reproduce asexually by forming new plantlets on the ends of stolons (runners) fungi such as single celled yeasts produce asexually by mitosis
44
why is mitosis needed for growth and repair
all multicellular organisms grow by producing more cells that are genetically identical to each other and the parent cell from which they arose by mitosis
45
why is mitosis needed for tissue repair
wounds heal when growth factors are secreted by platelets and macrophages (wbc) and damaged cells of the blood vessel walls, stimulate the proliferation of endothelial and smooth muscle cells to repair damaged blood vessels