Mitosis Flashcards

1
Q

What is a chromosome

A

A DNA molecule folded and condensed

Wrapped around a histone protein in eukaryotes.

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2
Q

What forms after DNA replication

A

2 genetically identical sister chromatids

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3
Q

Where are sister chromatids attatched

A

At the centromere

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4
Q

Define homologous chromososome

A

Chromosomes with the same genes but potentially different alleles.

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5
Q

Diploid cells

A

Cells with homolgous pairs of chromosomes

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6
Q

Diploid is represented by…

A

2n

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7
Q

Haploid cells

A

Cells with only one copy of the pair of chromosmes,

Half the number of chromosomes than diploids.

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8
Q

Haploid cells are represented by…

A

n

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9
Q

What type of cells can’t divide

A

Specialised and fully differentiated cells
e.g
Red blood cells

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10
Q

What type of cells can divide

A

unspecialised cells

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11
Q

3 main stages of the cell cycle

A

Interphase, mitosis and cytokenisis

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12
Q

3 phases of interphase

A

G1
S
G2

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13
Q

G1 phase of interphase, what happens?

A

Cell increases in size and new proteins and enzymes are made for DNA replication.

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14
Q

S phase in interphase, what happens?

A

DNA replicates

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15
Q

G2 phase in interphase, what happens?

A

Cell gets ready for division, new proteins and organelles are made.

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16
Q

What stage of the cell cycle is where chromomes are not visible?

A

Interphase

17
Q

4 Stages of mitosis

A

Prophase, metaphase, anaphase, telophase

18
Q

Why is mitosis important

A

Allows organisms to grow
Allows organisms to replace cells in order to repair tissues
Results in genetically identical cells
Asexual reproduction in some organisms (not prokaryotes)

19
Q

What happens in prophase

A

Nuclear membrane breaks down
Centrioles move to the poles of the cell and make spindle fibres.
chromosomes condense and become visible.

20
Q

What happens in metaphase

A

Spindle fibres which attach to the centromere of each chromsome
Chromosomes align down the equtor of the cell.

21
Q

What happens in anaphase

A

Spindle fibres contract, dividing the centromere.

Sister chromatids are pulled apart to opposite poles pf the cell ( the chromatids appear as V shapes)

22
Q

What happens in telophase

A

Chromsomes reach the poles and the spindle fibres break down.
New nuclear membrane forms around the group of chromsomes
Chromosomes uncondense and begin to form chromatin again.

23
Q

What happens in cytokenisis

A

The cytoplasm divides; producing two genetically identical daughter cells

24
Q

Cell division in cancer

A

Uncontrolled cell division leading to tumours

25
Q

Cancer cells

A

Divide uncontrollably

Have a shorter cell cycle and divide more often.

26
Q

How are cancer cells dangerous

A

Unspecialised and have no function so they cause harm by damaging organs or blocking blood vessels to organs.

27
Q

What parts of the cell cycle to cancer treatments disrupt

A

DNA replication (interphase)
Spindle formation/contraction (prevents anaphase)
Cytokenisis

28
Q

Why do cancer treatments kill more cancer cells than healthy cells

A

Tumour cells divide more frequently than normal cells s the treatments target tumour cells more.