MITOSIS AND MEIOSIS Flashcards

(36 cards)

1
Q

what are the two basic stages of the cell cycle?

A

interphase and mitosis

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2
Q

what is the difference between M phase and interphase

A

in interphase the cell is growing and making DNA copies
in m phase the cell divides by separating its DNA and creates two new cells

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3
Q

what happens during the g1 phase

A

rapid growth

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4
Q

what happens during the g2 phase

A

manufacture of cell organelles and cell parts needed for cell division

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5
Q

what happens during the S phase

A

duplication of DNA

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6
Q

process of mitosis

A

(Interphase)
Prophase
Metaphase
Anaphase
Telophase (Cytokinesis)

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7
Q

what is the process of the cell cycle

A

interphase: g1, s phase, g2
mitosis (PMAT)

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8
Q

what is cytokinesis

A

a single cell divides into two cells; the cytoplasm becomes separated

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9
Q

what are the two main checkpoints in the cell cycle

A

g1 checkpoint and g2 checkpoint (and spindle assembly)

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10
Q

what should you check for in g1

A

cell size
nutrients
growth factors
DNA damage

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11
Q

what should you check for in g2

A

cell size
DNA replication

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12
Q

what should you check for when spindle fibers assemble

A

chromosomes attaching to spindle

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13
Q

what does nuclear division mean

A

nuclear division happens in the nucleus

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14
Q

what does cytoplasmic division mean

A

division that happens in the rest of the cell

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15
Q

why does DNA exist as chromatin in interphase

A

it gives easier access to the protein

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16
Q

why does DNA condense during mitosis

A

the DNA becomes easier to separate

17
Q

what happens in prophase

A

nucleolus and nuclear membrane disappear
chromatin coils to form visible chromosomes
threadlike spindle forms between the pair of centrioles
centrioles travel to opposite ends of the cell

18
Q

what happens in metaphase

A

sister chromatids line up in the middle of the cell (two sister chromosomes form double chromosomes)

19
Q

anaphase

A

sister chromatids separate and are now considered 2 single chromosomes

20
Q

telophase

A

centrioles and spindle fibers begin to disappear
chromosomes turn back into the hard to see chromatin
nuclear membrane and nucleolus re-appear

21
Q

chromatin

A

loosely coiled DNA (only in non-dividing)

22
Q

chromosomes

A

tightly coiled DNA (only in mitosis)

23
Q

sister chromatids

A

exact copy of chromosomes

24
Q

centromere

A

location where chromosomes are attached

25
kinetochore
protein that motor protein can grab
26
centriole
made of microtubules arranged in perpendicular cylinders found only in animal cells migrate to opposing sides to make sure daughter cells get right amount of chromosomes
27
mitotic spindle
rips chromosomes apart
28
microtubules
helps develop the mitotic spindle
29
what are the differences between plant and animal cell division
plants: plants have cell walls they don't have centrioles to they attach to the cell wall plants can't pinch so they have to build a new cell wall to separate the new cells animals: humans are "squishy" they have centrioles humans only have to pinch in the middle during cytokinesis to separate the new cells
30
what do some anti-cancer drugs target
kinetochore so they can't separate the chromosomes
31
what two things enable chromosomes to move toward the poles during anaphase
kinetochore and motor proteins
32
mitosis in mitotic spindle
prophase: centrioles migrate to opposite ends of the cell=poles spindle fibers attach to chromosomes metaphase: centromere of sister chromatids are arranged to face opposite poles chromosomes lined up in the middle of the cell anaphase: kinetochore microtubules shorten motor protein move the chromosomes along the microtubules non-kinetochore lengthen=cell elongates telophase (end of nuclear division) cytokinesis (cell division) spindle fibers break down
33
how does cancer relate to the cell cycle
cancer develops when cells lose the ability to regulate their cell cycle
34
what are hallmark characteristics of cancerous cells
immorality lack of contact inhibition loss of intended function
35
what are proto-oncogenes and what does it do
they make proteins properly regulate their cycle and speeds up the cell division
36
what are tumor suppressor genes and what does it do
they make tumor suppressor proteins that destroy cancerous cells and slows down cell division