Mixed 12

Question 1

Type of epithelial cell junction found in Blood brain Barrier

Answer 1

Tight junctions (zona occludens) made of claudina and occludins that prevent paracellular movement

Question 2

Embryologic structures affected in DiGeorge syndrome

Answer 2

3rd and 4th pharyngeal/branchial pouches

Affects parathyroid and thymus

Question 3

Specific surface marker for monocyte-macrophage cell lineage

Answer 3

CD14

Question 4

Activity of DNA polymerase III with 3’-5’ exonuclease function

Answer 4

Removing mismatched nucleotides

“Proofreading”

Question 5

Most abundant aminoacid found in collagen protein

Answer 5

Glycin 1/3

Rest of it hydroxyproline or hydroxylisine

Question 6

Infection presented as fever, fatigue, splenomegaly, myalgias, with a negative Monospot test

Answer 6

Cytomegalovirus mononucleosis

Question 7

Heterophile antibodies detected by agglutination of sheep or horse RBCs

Answer 7

Positive Monospot test