MKSAP-5 Flashcards

(36 cards)

1
Q

how is MAC diagnosed?

A

bone marrow biopsy or blood culture

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2
Q

How is brucellosis acquired

A

Drinking Raw, unpasteurized milk of goat, cattle

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3
Q

Erlichia chafensis lab findings

A

Thrombocytopenia
Leukopenia
Elevated LFTs

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4
Q

What is another name for heartland virus,

and what other bug and manifestation does it appear similar to?

How do you tell them apart?

A

Bandavirus

It is similar to erlichiosis

Give them Doxy, Heartland virus will not respond to Doxy but erlichia will!

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5
Q

A patient in___demographic should be hospitalized if you see shingles rash
(We are’s most patients with Shingles can be managed outpatient with p.o. antiviral)

___This is a treatment

A

Immunocompromised i.e. pregnant, transplant recipient

Acyclovir IV…!

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6
Q

What is the clinical course of the shingles rash, as and how does it present typically?

A

If for starts with pain and paresthesias in the skin area, in a few days rash Erupts Afterwards

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7
Q

When you have a shingles outbreak, what is the p.o. antiviral treatment due to benefit the rash?

How soon after shingles outbreak should you take it?

A

If shortens a duration of symptoms, also decreases the severity of symptoms

Taken within 72 hours after rash onset

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8
Q

Which fluoroquinolone is not a good respiratory fluoroquinolone

Which fluoroquinolone is not good for Pseudomonas coverage

A

Ciprofloxacin sucks for strep pneumo coverage

Moxifloxacin sucks for Pseudomonas

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9
Q

Curb 65, what does it include?

A

Pneumonia severity index
C-confusion

U-uremia i.e. BUN >20

R-respiratory rate ie RR >30

B-blood pressure <90/<60

65-age 65 and over

1 point for all

1: Treat outpatient
2: Moderate risk, consider inpatient treatment or outpatient with close follow-up
3 or MORE: Severe risk going patient! Maybe even ICU

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10
Q

Describe the complication of shingles AKA herpes zoster infection

As send what is the clinical presentation?

A

Ramsay Hunt syndrome

SYMPTOMS

-Zoster oticus:Erythematous vesicular rash on the ear,
Similar looking lesion in the mouth(HALF OF THE TONGUE!!!)

-Cranial nerve VIII involvement: Symptoms with hearing loss, tinnitus, nausea vertigo, nystagmus

-Cranial nerve VII involvement: Facial nerve palsy one-sided face Paralyzed involving forehead

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11
Q

Pathophysiology of invasive pulmonary aspergillosis

A

Aspergillus initially invade pulmonary blood vessels->they cause distal infarct in the tissue->hemoptysis at presentation

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12
Q

What is the differential diagnosis of infection induced facial nerve palsy?

A

Bell’s palsy from Lyme disease i.e. Borrelia

VZV i.e. shingles i.e. Ramsay Hunt syndrome

HSV-1

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13
Q

In a patient who is being treated for CHF exacerbation, what will be an indication to place a urinary catheter?

A

To monitor intake and output in a critically illpatient

Do not place 1 in a not critically ill patient!

To prevent CAUTI

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14
Q

Lab findings and Babesia

A

Thrombocytopenia
Hemolytic anemia
Jaundice, elevated LFT, Hepatomegaly
Splenomegaly

BLOOD SMEAR will NOT HAVE SHISTOCYTES

Blood smear: Intra erythrocytic rings

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15
Q

Positive galactomannan in a patient with pneumonia, think this bug

A

Invasive aspergillosis

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16
Q

Which 2 Candida bugs can actually cause invasive candidiasis?

A

Candida auris
Candida glabrata

Not not not not not Candida albicans! Normal respiratory flora it is!

17
Q

A patient who is immunosuppressed, has very very prolonged neutropenia, what bug are the added risk of getting?

A

Invasive aspergillosis

18
Q

What will you see on CT chest thorax for invasive pulmonary aspergillosis

A

Pulmonary infiltrates

Nodules with groundglass appearing around the nodule: The halo sign!

Wedge-shaped density-it is the infarct!

19
Q

Definitive diagnosis of invasive aspergillosis, how was it done?

A

Bronchoalveolar lavage and biopsy, either are very effective

Also very excellent is the serum galactomannan assay

20
Q

Babesia can be caused by this mode

A

Black Legged tic

Even transfusion reaction!

21
Q

What kind of immunocompromised patients are at a risk for invasive aspergillosis?

Why?

A

Receiving chemotherapy
Hematopoietic stem cell transplant

Both of these conditions can cause prolonged neutropenia

22
Q

To the patient with IBD i.e. Crohn’s or ulcerative colitis need prophylaxis when they are traveling overseas?

A

Yes!
Give them rifaximin for prophylaxis for traveler’s diarrhea

(Otherwise if the patient does not have a disease complication–Another one being CKD– that puts him at a high risk, do not give antibiotics just like that!)

23
Q

Most frequently acquired infection in international travelers?

And what Bugs does not involve?

A

Traveler’s diarrhea

ED tech E. coli
Campylobacter
Shigella
Salmonella
These above make up 80 to 90% of cases

Viruses i.e. rotavirus, norovirus

Some protozoal parasites i.e. Giardia

24
Q

Clinical presentation speaking, how you distinguish meningitis from encephalitis?

A

Patient with meningitis will be sick and uncomfortable, but normal brain function, will be awake and talking and alert oriented

With encephalitis they will be altered, may be obtunded, personality change, flaccid paralysis or focal paralysis, some kind of movement disorder

25
HSV 1 will present more with this CNS presentation HSV-2 will present in this way
HSV 1 will be mostly encephalitis HSV-2 will be mostly meningitis, They could have had some kind of genital lesion before it to
26
What is the positive West Nile diagnosis?
IgM antibody identified on the CSF or on the serum
27
How does the paralysis from West Nile present?
Can be asymmetric, can be symmetric, either way it is flaccid
28
After HIV exposure, approximately when to start getting the viral symptoms with the viral syndrome?I.e. the flulike symptoms
10 days to 2 weeks!
29
This initial screening test with the P 24 antibody antigen test for HIV, however early cannot start detecting HIV?
5 days after exposure
30
You suspect you have been exposed to HIV after finding out someone else has it, "point would it not be beneficial to start postexposure prophylaxis?
Start postexposure prophylaxis ASAP, but it will not be of benefit if you started 72 hours after exposure
31
In an immunocompetent patient get cerebral toxoplasmosis?
no
32
Cannon immuno competent patient given neurocysticercosis?
yes
33
Mode of transmission of neurocysticercosis
You ingested the egg of the pork tapeworm(Food or water) Taenia solium
34
Which fluoroquinolone has anaerobic coverage?
Moxifloxacin
35
What is the indication to provide with Antibiotic prophylaxis in a patient who has had a human bite?
Bite to the hand, Face, genital Immunocompromised patient i.e. elderly, diabetic Bite to the joint or bone Deep deep puncture Wound has a clear-cut edema or lymphatic/venous insufficiency
36
What antibiotic would you give for prophylaxis after a human bite?
Fluoroquinolone with Flagyl (Or moxifloxacin alone) Augmentin #1-the other alternatives if penicillin allergy Doxy with clindamycin or Flagyl