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Endocrinology > MKSAP Qbank > Flashcards

MKSAP Qbank Flashcards

(65 cards)

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1
Q

Three first line tests to establish hypercortisolism

A
  1. Late night salivary cortisol
  2. 24 hour urinary free cortisol
  3. Overnight DMT suppression test
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2
Q

How many tests are needed to establish hypercortisolism

A

2/3 first line tests

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3
Q

Monoclonal antibody for osteoporosis

A

Denosumab

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4
Q

Which medication should be started before stopping denosumab

A

Bisphosphonates

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5
Q

One lab diagnostic of myxedema coma?

A

Low free T4. Not TSH

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6
Q

Commonly administered in myxedema coma with levothyroxine

A

Empiric steroids for adrenal insufficiency

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7
Q

Lab to monitor levothyroxine dosage after pituitary resection

A

T4

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8
Q

Target FT4 for levithyroxine supplementation after pitutary resection

A

Mid to upper range of normal

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9
Q

Does alendronate improve BMD?

A

No

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10
Q

Nesidoblastosis

A

Post gastric bypass hypoglycemia

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11
Q

Clinically significant hypoglycemia

A

55

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12
Q

Relative hypoglycemia

A

Rapid correction of BG in a patient with persistently high BG

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13
Q

Hypoglycemia unawareness

A

Lack of autonomic response to low BG

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14
Q

Whipple’s triad

A

Hypoglycemia triad

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15
Q

4 tests for fasting hypoglycemia

A
  1. Insulin
  2. C peptide
  3. Pro insulin
  4. Beta hydroxy butyrate
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16
Q

Frequency of lab draws for fasting hypoglycemia

A

Every 6 hours

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17
Q

Frequency of plasma glucose measurement for PP hypoglycemia

A

Every 30 minutes * 5 hours after meal

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18
Q

Fasting BG for metabolic syndrome

A

100

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19
Q

TG for metabolic syndrome

A

150

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20
Q

DBP for metabolic syndrome

A

85

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21
Q

Waist circumference for metabolic syndrome

A

35 F and 40 M

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22
Q

Weight loss goal for DM

A

7% in 6 months

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23
Q

When should you not target a HbA1c

A

Life expectancy <10 years

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24
Q

Side effect of thiazolidinediones

A

CHF

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25
Fournier gangrene is a SE of which hypoglycemic agent
SGLT-2
26
2 lab abnormalities seen with Metformin
1. Lactic acidosis 2. B12 deficiency
27
Insulin dose in T2DM
0.1-0.5
28
Insulin in type 1 DM
0.4-1unit/kg
29
Most incidentally discovered adenomas are ——-
Benign
30
What are the two ways to classify a pitutary adenoma
1. Micro and macro 2. Functioning and non functioning
31
Duration for denosumab
10 years
32
What is MACE
Mild autonomous cortisol excess; adrenal ACTH independent production of cortisol without features of fishing’s
33
Three drugs for neuropathic pain
1. Pregablin 2. Gabapentin 3. Cymbalta
34
Common pain medication causing hypogonadism
Opiates by suppressing GnRH
35
Medications causing hyperprolactenemia
Anti psychotics and metoclopropamide
36
Rx of med related hyper prolactinemia
1. Stop if possible 2. If cannot be stopped —> put Stuart MRI to evaluate for adenoma 3. Hormone replacement to Rx symptoms 4. DO NOT GIVE CABERGOLINE DUR TO WORSENING OF PSYCH SYMPTOMS
37
When to Re image pitutary adenoma after starting therapy
3 months and then every 6-12 months
38
Asymptomatic pitutary micro adenoma Rx
None
39
Mainstay Rx or acromegaly
Surgery
40
Drug Rx of acromegaly
Pegvisomant
41
Difference between Cushing disease and syndrome
Disease: pitutary source Syndrome: any source
42
Diagnosis DI
1. High serum osmolarity and Na 2. Low urine osmolarity 3. Water deprivation
43
Diff central from nephrogenic DI
Desmopressin supression
44
2 medications causing hyperCa
1. Lithium 2. Thiazides
45
What is tertiary huperPTH
CKD patients with chronic secondary hyperPTH develop PTH hyperplasia leading to autonomous PTH production
46
Familial hypocalciuric hupocalcemia gene mutation
Calcium sensing R gene
47
2 other endocrine disorders causing high Ca
Throtoxicosis and Addison crisis
48
When should rheum screen for osteoporosis
Steroids for >6 months 1. <40 yr + risk factors 2. >40 yr
49
Common side effect of zolendronic acid
First insulin fever and myalgia —> does not recur
50
Contraindication for bisphosphonate
GFR <35
51
Recombinant PTH for osteoporosis
Teri pertained and abaloparatide
52
Max duration for recombinant PTH in osteoporosis
2 years
53
Sclerotin inhibitor
Romosuzumab
54
Contraindication of romosuzumab
CVD
55
Which hormone levels should be tested in all patients with adrenal incidentaloma
Cortisol levels
56
When should pheo testing be done for incedentaloma
>10 hounsfield unit on CT abdomen
57
What are the characteristics of benign adrenal incedentaloma
1. Size <4 cm 2. Hounsfield units <10 3. Contrast washout >60% in 10 minutes
58
Which anti thyroid medication is used acutely and which is maintainance
PTU - promote recovery Methimazole - maintain
59
Endocrine abnormalities progression after pitutary resection
DI post op —> SIADH in 7-10 days —> DI permanent
60
Which two drugs lead to false results on RAIU scan?
Lithium and Amiodarone
61
Proxy for HBA1c in patients with hemolytic anemia
Frustosamine
62
Remember situations when HBA1c is not useful
1. Hemolytic anemia 2. Blood transfusion 3. Hemoglobinopathies
63
Contraindications for GLP-1
1. Pancreatic CA/pancreatitis 2. MEN syndrome
64
Predominant hormone regulating PO4
FGF-23
65
Which electrolyte deficiency can lead to low PTH secretion
Mg

Endocrinology (1 decks)

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