MKSAP STOCK3

Question 1

What is the additional treatment indicated in all patients with small cell lung cancer who experience a remission following chemotherapy and radiation therapy to the chest?

Answer 1

Prophylactic Cranial Irradiation

Question 2

What is the treatment indicated for patients with recurrent Hodgkin lymphoma who achieve a complete response to salvage chemotherapy?

Answer 2

Autologous Hematopoetic stem cell transplant

Question 3

What is the recommended imaging surveillance following treatment of early-stage breast cancer in asymptomatic patients?

Answer 3

Annual mammography

Question 4

What is the therapeutic option for patients with bone-limited, symptomatic metastatic prostate cancer?

Answer 4

Radiopharmaceutical agent Radium 223

Question 5

What is the recommended additional postsurgical therapy for patients with early-stage, triple-negative breast cancer >0.6 cm?

Answer 5

Chemotherapy (often anthracycline based)

Question 6

What is the recommended breast cancer screening regimen for women who received chest wall radiation between ages 10 and 30 years?

Answer 6

Annual mammogram and breast MRI

Question 7

What adjuvant treatment following surgical resection is shown to improve survival in patients with stage II or stage III non-small cell lung cancer?

Answer 7

Cisplatin based chemotherapy

Question 8

What is the optimal method of tissue sampling to diagnose lymphoma?

Answer 8

Excisional lymph node biopsy

Question 9

What is the recommended strategy for an older man with significantly limited life expectancy (<10 years) with newly diagnosed low risk prostate CA?

Answer 9

Clinical Observation

Question 10

What is the standard treatment regimen for patients with stage I, II, or III anal squamous cell carcinoma?

Answer 10

Chemoradiation (w/ mitomycin C)

Question 11

What is the mgmt for incidentally discovered, low grade, hormonally nonfunctional, metastatic carcinoid tumor?

Answer 11

Expectant observation with periodic repeat imaging

Question 12

What is the management of patients with imaging compatible with resectable pancreatic cancer

Answer 12

Definitive resection WITHOUT previous tissue confirmation

Question 13

Appropriate management strategy in patients with a history of treated breast cancer who develop findings suspicious for metastatic disease

Answer 13

Biopsy of suspected metastatic site to confirm diagnosis and to assess hormone receptor status and HER2 status

Question 14

Management of a patient with metastatic cancer and poor performance status

Answer 14

Palliative care

Question 15

What is the most likely diagnosis in a patient with microscopic hematuria, midback pain, erythrocytosis, and elevated erythropoetin

Answer 15

Renal Cell Carcinoma

Question 16

Adjuvant therapy shown to improve outcomes in patients with high risk, localized gastrointestinal stromal tumors

Answer 16

Imatinib

Question 17

Definition of neutropenic fever in patients undergoing cancer treatment

Answer 17

Fever w/ neutrophil count <1000 (often, actually <500)

Question 18

What is the recommended management of men with persistently elevated prostate-specific antigen level immediately following radical prostatectomy

Answer 18

Androgen Deprivation Therapy

Question 19

What is the recommended initial treatment of patients with early-stage head and neck cancer?

Answer 19

Either surgery or primary radiotherapy

Question 20

Treatment for metastatic recurrence of pancreatic cancer in patients with good performance status

Answer 20

Multiagent Systemic Chemotherapy

Question 21

Most common metabolic complication associated with Burkitt lymphoma

Answer 21

Tumor lysis syndrome

Question 22

What is the recommended treatment for high-grade, poorly differentiated neuroendocrine tumors of unknown primary site

Answer 22

Platinum-based systemic chemotherapy

Question 23

Recommended adjuvant endocrine therapy following breast cancer treatment for a premenopausal woman?

Answer 23

Tamoxifen for AT LEAST 5 years but PREFERABLY 10 years

Question 24

What is the treatment of choice for hyperuricemia in a gout patient with an adverse reaction to allopurinol?

Answer 24

Febuxostat

Question 25

What is a nonerosive arthritis associated with systemic lupus erythematosus?

Answer 25

Jaccoud Arthropathy

Question 26

The combination of these two laboratory tests has the greatest specificity for diagnosing rheumatoid arthritis

Answer 26

Anti-CCP; Rheumatoid factor

Question 27

What is the type of dermatomyositis with cutaneous involvement in the absence of clinical, laboratory, electromyogram, or biopsy evidence of muscle inflammation?

Answer 27

Amopathic Dermatomyositis

Question 28

Treatment for inadequately controlled osteoarthritis in one symptomatic joint

Answer 28

Intra-articular glucocorticoids

Question 29

What is the treatment for acute monoarticular gout when oral therapies have potential adverse event

Answer 29

Intra-articular glucocorticoids

Question 30

What is the treatment of severe Henoch Schonlein Purpura with multi-organ system involvement

Answer 30

Glucocorticoids

Question 31

What is the indication for use of multiple biologic agents to treat rheumatologic disease?

Answer 31

None if you're going to use them you just use one

Question 32

What are four symptoms that must be present for \>3 months in order to diagnose fibromyalgia

Answer 32

Chronic widespread pain, fatigue, waking up unrefreshed, and cognitive symptoms

Question 33

Neonatal cardiac complication of maternal systemic lupus erythematosus with positive anti-Ro/SSA antibodies

Answer 33

Congenital Heart Block

Question 34

Underlying cause of secondary osteoarthritis of metacarpophalangeal and wrist joints

Answer 34

Hemochromatosis

Question 35

What is the most sensitive imaging test for diagnosing suspected spondyloarthritis

Answer 35

MRI of spine and sacroiliac joints

Question 36

What is the test of choice for pulmonary hypertension in patients with underlying rheumatologic disease?

Answer 36

Echocardiography

Question 37

Pulmonary disease associated with polymyositis and positive anti-Jo-1 antibodies

Answer 37

Interstitial Lung Disease

Question 38

What biologic agent is associated with the risk of an abnormal lipid panel

Answer 38

Tofacitinib (Xeljanz)

Question 39

What is the target serum urate level for secondary prevention of gout?

Answer 39

\<6.0

Question 40

What is the initial treatment of patients with suspected giant cell arteritis?

Answer 40

High dose prednisone (60 mg daily)

Question 41

What is the preferred tuberculosis screening for patients starting a biologic agent who are already on nonbiologic immunosuppressive therapy?

Answer 41

Interferon gamma release assay

Question 42

What disease is characterized by inflammatory back pain and stiffness in the lower spine that worsens after immobility and improves with use

Answer 42

Ankylosing Spondylitis

Question 43

What connective tissue disease has a markedly increased risk of developing lymphoma?

Answer 43

Sjogren syndrome

Question 44

What serologic test is useful in patients with an intermediate probability of having spondyloarthritis?

Answer 44

HLA-B27

Question 45

What disease is diagnosed by fever, polyserositis, and arthritis that improves with a trial of colchicine

Answer 45

Familial Mediterranean Fever

Question 46

What antidepressant medication has shown to reduce pain and improve functioning in patients with knee osteoarthritis

Answer 46

Duloxetine

Question 47

Treatment of choice for interstitial lung disease associated with diffuse systemic sclerosis?

Answer 47

Cyclophosphamide

Question 48

What is the test of choice to diagnose the cause of acute monoarticular arthritis?

Answer 48

Synovial Fluid Analysis

Question 49

What are six clinical characteristics of psoriatic arthritis

Answer 49

Enthesitis, Dactylitis, Tenosynovitis, Arthritis of the distal interphalangeal joints, asymmetric oligoarthritis, and spondylitis

Question 50

What disease is characterized by eosinophilia, MIGRATORY pulmonary infiltrates, purpuric skin rash, and mononeuritis multiplex

Answer 50

Eosinophilic Granulomatosis with Polyangiitis