Flashcards in Mock MCQs Deck (16):
What antibiotic is used in a man with pneumonia and an amoxicillin allergy?
Which of the following is a characteristic of staph aureus?
- common cause of UTI
- gram negative
- grows in chains
- production of coagulase
- usually sensitive to amoxicillin
Production of coagulase
Which of the following is a live vaccine?
Mumps (part of the MMR live vaccine)
What is the most common route of HIV transmission globally?
What is the mechanism of aciclovir?
Inhibition of DNA polymerase
What are the components of the CURB-65 score?
C - confusion present?
U - urea levels over 7mmol/l
R - respiratory rate over 30 breaths per min
B - systolic < 90mmHg or diastolic <60mmHg
65 - being 65 years old or over
What is the most likely cause of a shallow painless ulcer on the penile shaft, with no associated lymphadenopathy?
Describe the SEPSIS 6.
FBC and lactate
Monitor urine output
Which organisms are most commonly associated with intra-abdominal sepsis?
Describe the LPS virulence factor
Lipopolysaccharides are a membrane constituent with lipid and sugar components
This activates immune cells via TLR-4 leading to inflammatory cascade
What empirical antibiotics and route would you prescribe for the diagnosis of intra-abdominal sepsis?
Amoxicillin, gentamicin and metronidazole
Name two common causative organism of skin and soft tissue infection (numerous white blood cells and gram-positive cocci).
Which empirical antibiotic and route would you prescribe for a patient with a serious beta-lactam allergy with a mild skin/soft tissue infection who is systemically well?
Clarithromycin or doxycycline
Describe the mechanism of action of the beta-lactam group of antibiotics.
Bind to and inhibit action of penicillin binding proteins (enzymes) involved in cell wall biosynthesis
Name the class of enzyme that confers resistance to the majority of beta-lactam antibiotics.
Extended spectrum beta-lactamase