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Flashcards in Mock MCQs Deck (16):
1

What antibiotic is used in a man with pneumonia and an amoxicillin allergy?

Levofloxacin

2

Which of the following is a characteristic of staph aureus?
- common cause of UTI
- gram negative
- grows in chains
- production of coagulase
- usually sensitive to amoxicillin

Production of coagulase

3

Which of the following is a live vaccine?
- diptheria
- HPV
- mumps
- pneumococcal
- tetanus

Mumps (part of the MMR live vaccine)

4

What is the most common route of HIV transmission globally?

Heterosexual sex

5

What is the mechanism of aciclovir?

Inhibition of DNA polymerase

6

What are the components of the CURB-65 score?

C - confusion present?
U - urea levels over 7mmol/l
R - respiratory rate over 30 breaths per min
B - systolic < 90mmHg or diastolic <60mmHg
65 - being 65 years old or over

7

What is the most likely cause of a shallow painless ulcer on the penile shaft, with no associated lymphadenopathy?

Treponema pallidum

8

Describe the SEPSIS 6.

Oxygen
Blood cultures
Antibiotics
IV fluid
FBC and lactate
Monitor urine output

9

Which organisms are most commonly associated with intra-abdominal sepsis?

Gram negatives
Anaerobes

10

Describe the LPS virulence factor

Lipopolysaccharides are a membrane constituent with lipid and sugar components
This activates immune cells via TLR-4 leading to inflammatory cascade

11

What empirical antibiotics and route would you prescribe for the diagnosis of intra-abdominal sepsis?

Amoxicillin, gentamicin and metronidazole

12

Name two common causative organism of skin and soft tissue infection (numerous white blood cells and gram-positive cocci).

Staph aureus
Strep pyogenes

13

Which empirical antibiotic and route would you prescribe for a patient with a serious beta-lactam allergy with a mild skin/soft tissue infection who is systemically well?

Clarithromycin or doxycycline
- oral

14

Describe the mechanism of action of the beta-lactam group of antibiotics.

Bind to and inhibit action of penicillin binding proteins (enzymes) involved in cell wall biosynthesis

15

Name the class of enzyme that confers resistance to the majority of beta-lactam antibiotics.

Extended spectrum beta-lactamase

16

What empirical antibiotics would you prescribe to someone with a severe, rapidly progressing wound infection?

Flucloxacillin, benzylpenicillin, clindamycin, gentamicin and metronidazole
- IV