MOD4 Flashcards
(34 cards)
1
Q
4 features of signal transduction
A
1
Q
2 types of receptors
A
2
Q
2 major typs of cellular responses
A
3
Q
arrow meaning (activation, inactivation, inhibitor)
A
4
Q
4 ways to turn signals on/off
A
5
Q
5 molecular switches
A
6
Q
phosphorylation
A
7
Q
phosphorylation vs GTP-binding proteins
A
8
Q
degradation by proteasome
A
9
Q
pathway 1: GPCR
A
10
Q
b-adrenegric pathway
A
11
Q
examples of kinase turn on/off
A
12
Q
effect of cAMP on PKA
A
13
Q
CREB + CRE
A
14
Q
how is the PGCR pathway turned OFF
A
15
Q
where is GTP hydrolysed in GPCR pathway
A
16
Q
desensitisation of B-adrenergic receptors
A
17
Q
pathway 2: RTK
A
18
Q
phosphorylation of TRK
A
19
Q
GTPASE on/off
A
20
Q
GTPase RAS
A
21
Q
MAPK pathway
A
22
Q
MAPkkk-MAPkk-MAPk cascade
A
23
Q
what if ras constitutively ON
A
24
4 ways to terminate P2:RTK
25
cytokine receptors
26
pathway 3: cytokine receptor
27
P3-Jak-STAT
28
termination of JAK-STAT
29
pathway 4: TNF-a
30
NF-Kb
31
western blot (refer to image)
32
EGF pathway
33
co-immunoprecipitation
