Modern Developments in Microbiology

Question 1

Poliomyelitis can grow in cultures

Answer 1

Enders
Weller
Robbins

Question 2

Yellow Fever

Answer 2

Theiler

Question 3

Genetic structure and replication of bacteriophage

Answer 3

Delbruck
Hershey
Luria

Question 4

Tyhpus -> Lice

Answer 4

Nicolle

Question 5

HIV

Answer 5

Sinoussi
Luc Montagnier

Question 6

Helicobacter pylori

Answer 6

Marshall
Warren

Question 7

Tuberculosis

Answer 7

Koch

Question 8

Diphtheria

Answer 8

Von Behring

Question 9

Genetic recombination of bacteria

Answer 9

Lederberg

Question 10

Retroviral oncogenes

Answer 10

Bishop
Varmus

Question 11

Viruses can cause animal cancer

Answer 11

Huggins
Roux

Question 12

Malaria

Answer 12

Ross

Question 13

Penicillin

Answer 13

Fleming
Florey
Chain

Question 14

Sulfa drugs

Answer 14

Domagk

Question 15

Streptomycin

Answer 15

Waksman

Question 16

Human papilloviruses

Answer 16

Hausen

Question 17

Malariotherapy for late stage of syphilis

Answer 17

Wagner-Jeuregg

Question 18

Prions

Answer 18

Prusiner

Question 19

Mosquito - Malaria

Answer 19

Laveran

Question 20

First prototype electron microscope capable of four-hundred-power magnification
400x

Answer 20

Knoll
Ruska

Question 21

One gene-one enzyme hypothesis

Answer 21

Beadle
Tatum

Question 22

Genetic mutation “arises in the absence” of selection

Answer 22

Luria
Delbruck

Question 23

Streptomycin produced by two strains of actinomycete, Streptomyces griseus

Answer 23

Waksman

Question 24

DNA is the substance that causes bacterial transformation
It was first described in Griffith’s experiment of 1928.

Answer 24

Avery
MacLeod
McCarty

Question 25

DNA model, which is now accepted as the first correct model of the double-helix

Answer 25

Watson Crick

Question 26

Radioactively labelled hybridisation probes

Answer 26

Joseph Gall Mary Lou Pardue

Question 27

More user-friendly fluorophores replaced the radioactive labels leading to the development of

Answer 27

Fluorescence in situ hybridisation (FISH)

Question 28

They are DNA or RNA fragments that can bind to complementary sequences in the microbial chromosome

Answer 28

Hybridisation probes

Question 29

Ribosomal genes that led to the first scientifically based tree of life

Answer 29

Carl Woese

Question 30

small 16S ribosomal RNA subunit for: 18S rRNA subunit for:

Answer 30

bacteria eukaryotic organisms

Question 31

Eradicates smallpox

Answer 31

World Health Organization

Question 32

HIV as causative agent of AIDS

Answer 32

Luc Montaigner Robert Gallo

Question 33

Polymerase chain reaction (PCR) - enables a target stretch of DNA to be copied thousands or millions of times.

Answer 33

Kary Mullis