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term 4 integ lorello > module 1 integ term 4 lorello 2nd lecture of stuff > Flashcards

module 1 integ term 4 lorello 2nd lecture of stuff Flashcards

(54 cards)

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1
Q

what is thicker ? epidermis or dermis?

A

dermis

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2
Q

dermis supports the epidermis and helps bind it to the subcutaneous tissue, true or false?

A

true

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3
Q
  • Connective tissue that supports the epidermis and binds it to the
    subcutaneous tissue (hypodermis)
  • Thickness varies (up to 4-5mm) (eyelids the dermis is very thin but on your back the dermis is very thick)
  • Surface is irregular with projections known as dermal papille
  • Dermal papillae
  • Interdigitate with epidermal projections
  • Rete pegs
A

Dermis

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4
Q

dermis surface is irregular with projections known as ________

A

dermal papillae

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5
Q

this structure interdigitate with epidermal projections (rete pegs)

A

dermal papillae

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6
Q

rete pegs are in the ______ and dermal papillae are in the _______

A

rete pegs are in the Epidermis and dermal papillae are in the Dermis

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7
Q

rete pegs are projections from the epidermis that interdigitate with what dermal component ? when these two structures interdigitate they hold the dermis and epidermis together

A

rete pegs from the epidermis work with the dermal papillae from the dermis

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8
Q

The basement membrane is between the stratum basal of the epidermis and papillary layer of the dermis

stratum basal of EPIDERMIS
basement layer
papillary layer of DERMIS

is the epidermis avascular ?

A

yes

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9
Q

The basement membrane is between the stratum basal of the epidermis and papillary layer of the dermis

stratum basal of EPIDERMIS
basement layer
papillary layer of DERMIS

how do the keratinocytes receive nutrients if the epidermis is avascular ?

A
  • Nutrients for keratinocytes diffuse into the avascular epidermis from the dermis vasculature through the basement membrane
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10
Q

BULLOUS PEMPHIGOID

A
  • Autoimmune disorder
  • Formation of blisters at the
    epidermal/dermal junction

BULLS (bullous) running through the hills between the dermis and the epidermis can give you BULLOUS PEMPHIGOID

youll get Blister Bumps called Bullous Pemphigoid if the bumps between the epidermis and dermis Buldge

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11
Q

the thickest skin is at the palms and soles of feet and they have ridges called ______ ridges

A

Dermal ridges

excuse me, your dermal ridges are showing

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12
Q

Dermal ridges

A
  • Found in thick skin
  • Parallel arrangement with dermal
    papillae in-between
  • Form a distinctive pattern
  • Finger prints
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13
Q

a parallel arrangement with dermal papillae in between and form a distinctive pattern which are your finger prints

A

Dermal ridges

a distinctive pattern of dermal ridges = fingerprints
stratum corneum = top layer of epidermis

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14
Q

papillary layer

A

most superficial layer of dermis, the top

papillary layer = top layer of dermis
stratum corneum = top layer of epidermis

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15
Q
  • Composed of loose connective tissue, fibroblasts, mast cells, and macrophages
  • Embedded in a gelatinous matrix (ground substance)
  • Anchoring fibrils of type VII collagen insert into the basal lamina
  • Collagen accounts for >70% of skin’s dry weight
A

papillary layer

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16
Q

dermis, bone, tendon, fascia, sclera, IV discs

which type of collagen?

A

1

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17
Q

hyaline and elastic cartilage

which type of collagen?

A

2

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18
Q

smooth muscle, arteries, lung, uterus, kidney

which type of collagen?

A

3

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19
Q

skin

cartilage

smooth muscle of arteries

collage?

A

1 skin

2 cartilage

3 smooth muscle of arteries

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20
Q

dermis / tendon / sclera / IV disc?

hyaline and elastic cartilage ?

lung / uterus / kidney ?

collagen?

A

1 dermis / tendon / sclera / IV disc

2 hyaline and elastic cartilage

3 lung / uterus / kidney

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21
Q

Reticular layer of dermis

A

thicker layer composed of dense connective tissue (type 1)
network of elastic fibers (elastin)

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22
Q
  • Major cell types
    *Fibroblasts
    Produce Collagen and Elastin
  • Macrophages
    Help fight infection
  • Mast cells
    Specialized secretory cells
    Produce chemical mediators of inflammation

which layer of dermis ?!! hint - this is the area of dense Collagen and Elastin

Study These Flashcards
A

Reticular layer

reticular layer sounds like it has elastin and type 1
collagen

Reticular layer
Dense connective tissue

papillary layer
loose connective tissue

I think papillary layer has similar cells but this one is dense

23
Q

Reticular layer of dermis

Study These Flashcards
A
  • Site of hair follicles and sebaceous glands
  • Network of blood and lymphatic vessels
  • Rich supply of nerves
  • Effector (motor) nerves to dermal structures
  • Affector (sensory) nerves around hair follicles
24
Q

which layer of skin?

Rich supply of nerves
* Effector (motor) nerves to dermal structures
* Affector (sensory) nerves around hair follicles

Study These Flashcards
A

Reticular layer of dermis

25
sebaceous glands are epidermal _________ (cool lorello phrase)
derivatives
26
* Plexus at the hypodermis and dermis * Plexus between the papillary and reticular layers
blood supply for these areas Plexus = network of nerves or vessels in body
27
* Root hair plexus Detects hair movement * Tactile (Meissner) corpuscles Detect light touch * Pacinian corpuscles Deep pressure, vibration * Krause end bulb Mechanoreceptor Cold temperature * Ruffini corpuscles Stretch
sensory receptors in dermis
28
Ruffini corpuscles
sense stretch To remember that Ruffini corpuscles respond to skin stretch, sustained pressure, and changes in joint position, you can use the mnemonic "Ruffini - Stretch and Sustained". Think of them as "ruffing" or "wrinkling" the skin and detecting that change.
29
ruffing up or wrinkling the skin and detecting change
ruffini corpuscles
30
Meissner corpuscles
tactile sense / detect light touch Messi has a light touch and great sense
31
Pacinian corpuscles
Deep pressure, vibration Pacific ocean is deep and always has water vibrations
32
Krause end bulb
* Mechanoreceptor * Cold temperature Santa Krause is cold !
33
Root hair plexus
* Detects hair movement
34
as i gently touch something my _______ kicks in as i push harder my _______ kicks in as i push harder to get a stretch my ________ kicks in
meissner (tactile) Pacinian Ruffini
35
Epidermal Derivatives * Epidermal appendages * Niche of epidermal stem cells Hair follicles Sebaceous glands * When the epidermis is injured epidermal stem cells reprogram and migrate toward the wound surface
epidermal stem cells from hair follicles , from sebaceous glands, will migrate towards the wound surface and will help regenerate the epidermis
36
* Elongated keratinized structure derived in the hair follicle * Present over almost the entire body * Influenced by hormones * Follicle serves as insertion for Sebaceous gland Arrector pili muscle
hair
37
hair follicle serves as insertion for
sebaceous gland arrector pili muscle
38
The ________ muscle is a tiny, smooth muscle connected to each hair follicle and the skin. When these muscles contract, they cause the hair to stand upright, creating the "goosebump" effect. This contraction is primarily triggered by cold or emotional stress, but can also be influenced by other factors like fear or excitement
arrector pili muscle
39
* 100 per cm2 * # 400-900/cm 2 face and scalp * Produce SEBUM * Complex mixture of lipids * Maintain stratum corneum and hair * Weak antibacterial and antifungal properties
sebaceous glands
40
SEBUM, from sebaceous glands
complex mixture of lipids that help keep your skin healthy and intact and helps maintain hair as well
41
Sweat Glands
* Eccrine sweat glands Distributed over the entire body * Apocrine sweat glands Axilla, areola and nipple, external genitalia, anus Connected to the hair follicle Produce protein enriched secretion containing pheromones and get bacteria in here a lot why these areas tend to smell quite a bit
42
found at Axilla, areola and nipple, external genitalia, anus Connected to the hair follicle Produce protein enriched secretion containing pheromones and get bacteria in here a lot why these areas tend to smell quite a bit
apocrine sweat glands
43
eccrine sweat glands
distributed over entire body while apocrine sweat glands are at the axilla areola nipple external genitalia and ANUS
44
What sweat gland is at ANUS
Apocrine sweat glands
45
* Physiologic response to increase body temperature/stress * Most effective means of temperature regulation * Produce 10L/day * Eccrine glands respond to temperature * Apocrine glands respond to emotional and sensory stimuli
sweat glands
46
___________ glands respond to emotional and sensory stimuli
apocrine glands - @ anus/axilla
47
___________ glands respond to temperature
Eccrine glands - @ everywhere Eccrine glands - Everywhere Apocrine glands - Anus and other places
48
* Plates of keratinized cells * Rest on nail beds * Epithelial cells that are continuous with stratum basal and stratum spinosum * Can often be a clue to systemic disease
Nails
49
windows into the health of your patient
nails
50
51
longitudinal linear lesions
on nails * Constitute 50 percent of melanomas in dark- skinned populations
52
HALF AND HALF NAILS indicate which organ is failing?
kidney renal failure
53
* Chronic renal failure * Proximal nail turns white * Distal nail becomes darker
HALF AND HALF NAILS
54
CYANOTIC CHANGES
* Lack of oxygen in the blood causes a bluish discoloration * Can be the result of congenital heart disease or pulmonary disease

term 4 integ lorello (3 decks)

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