module 1.2 Flashcards

(79 cards)

1
Q

What can cause pain during an injection?

A

Rapid injection, dull needle, or injecting into inflamed tissue.

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2
Q

What is trismus and what causes it?

A

Trismus is prolonged muscle spasm or limited jaw opening, often due to trauma to muscles or blood vessels.

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2
Q

What is a hematoma and which injection commonly causes it?

A

A hematoma is caused by puncturing a blood vessel; it often occurs during the PSA injection.

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3
Q

How can facial nerve paralysis occur during dental anesthesia?

A

By accidentally injecting anesthetic into the parotid gland during an inferior alveolar nerve block.

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4
Q

What causes needle breakage during injections?

A

Sudden patient movement or inserting the needle all the way to the hub.

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5
Q

What are post-anesthetic intraoral lesions?

A

Aphthous ulcers or herpes simplex virus outbreaks caused by tissue trauma from the injection.

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6
Q

What do afferent nerves do?

A

Carry sensory information from the periphery to the central nervous system.

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7
Q

What do efferent nerves do?

A

Transmit motor responses from the central nervous system to muscles or glands.

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8
Q

Which type of nerve fibers mediate pain perception during dental procedures?

A

Afferent (sensory) fibers.

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9
Q

Identify the properties of an ideal anesthetic

A

Potent and effective in small doses

Reversible action for safe patient recovery

Rapid onset and sufficient duration of anesthesia

Non-toxic, non-irritating to tissues

No allergic reactions, stable in solution, long shelf life

Easily metabolized and excreted, minimizing systemic accumulation

Low cost for clinical practicality

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10
Q

Recognize methods of inducing anesthesia

A

Topical Anesthetics: Surface application (e.g., benzocaine, Oraqix)

Infiltration and Block Injection: Most common in dentistry

Pharmacologic Sedation: Diazepam, nitrous oxide, Halcyon

Physical Methods: Ice (cryotherapy), pressure

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10
Q

What is local anesthesia?

A

A reversible loss of sensation in a defined area caused by pharmacologic depression of nerve function; the patient remains conscious.

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11
Q

Where are esters metabolized?

A

In the plasma by pseudocholinesterase.

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11
Q

Where are amides metabolized?

A

In the liver.

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12
Q

Which type of anesthetic has a higher allergy potential?

A

Esters.

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13
Q

Which type of anesthetic is more commonly used for topical application?

A

Esters (e.g., benzocaine).

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14
Q

Which type of anesthetic is more stable in solution?

A

Amides.

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15
Q

Which anesthetic type is commonly used for injections?

A

Amides (e.g., lidocaine, articaine).

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16
Q

Which anesthetic type has a longer shelf life?

A

Amides.

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17
Q

What is the resting potential of a neuron?

A

The membrane is polarized: inside is negative, outside is positive.

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18
Q

What happens during depolarization?

A

Sodium (Na⁺) channels open, sodium floods into the cell, and an action potential is generated (pain signal).

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19
Q

What occurs during repolarization?

A

Potassium (K⁺) exits the cell, and the membrane returns to resting potential.

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20
Q

How does local anesthesia affect sodium channels?

A

It binds to sodium channels and blocks Na⁺ influx.

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21
Q

What ion does local anesthesia compete with at receptor sites?

A

Calcium (Ca²⁺).

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22
How does local anesthesia prevent pain signal transmission?
By preventing depolarization, which blocks the action potential.
23
What is the pH nature of local anesthesia?
It is a weak base (pH ~4.5).
24
What is the normal pH of human tissue?
Slightly basic, around pH 7.4.
25
How does an infection (e.g., abscess) affect tissue pH?
It lowers the pH, making the area more acidic (~pH 6.5).
26
How does an acidic environment affect local anesthesia?
It reduces its effectiveness.
27
Where should you inject local anesthesia in the presence of infection?
Around, not into, the infected area.
28
How does absorption of local anesthesia vary by location?
It is faster in highly vascular areas and slower when vasoconstrictors are used.
29
Where is local anesthesia distributed first?
To highly perfused organs like the brain, heart, and liver.
30
Organs affected by anesthetic toxicity?
CNS (seizures, excitability), CVS (arrhythmias, hypotension)
30
How are local anesthetics excreted?
Primarily through the kidneys.
31
What is the approximate half-life of lidocaine?
About 1.6 hours.
32
Benefits of using vasoconstrictors:
Reduces systemic absorption Prolongs anesthetic duration Enhances depth of anesthesia Controls bleeding (hemostasis)
33
Vasoconstrictors in dentistry:
Epinephrine: most common, ratios: 1:50,000; 1:100,000; 1:200,000 Levonordefrin (Neo-Cobefrin): synthetic, 1/5 as potent, 1:20,000
34
What is the maximum epinephrine dose for a healthy patient?
0.2 mg
35
What is the maximum epinephrine dose for a cardiac patient?
0.04 mg
36
How much epinephrine is in one cartridge of lidocaine 1:100,000?
0.018 mg per cartridge
37
How many cartridges of lidocaine 1:100,000 can a healthy patient safely receive?
About 11 cartridges
38
How many cartridges of lidocaine 1:100,000 can a cardiac patient safely receive?
About 2 cartridges
39
Define half-life:
The time it takes for 50% of the drug to be eliminated from the body
40
What cardiovascular conditions require reduced anesthetic/vasoconstrictor doses or medical consultation?
ASA III-IV classification, recent myocardial infarction, stroke, or severe arrhythmias.
41
When is local anesthesia with vasoconstrictors absolutely contraindicated due to blood pressure?
Severe hypertension, BP ≥ 200/115 mmHg.
42
Why must epinephrine be used cautiously with non-selective beta-blockers like propranolol?
Risk of hypertensive crisis from unopposed alpha-adrenergic stimulation.
43
How do you differentiate between Beta-Blockers that are Nonselective?
OLOL Meds beginning with A-M are selective! S=SAFE Meds beginning with N-Z are non selective! NS=NOT SAFE
44
What are non selective beta blockers used for?
Used for hypertension Migraines
45
How do tricyclic antidepressants affect vasoconstrictor use?
Increase sensitivity, risk arrhythmias; use minimal epinephrine, avoid levonordefrin and norepinephrine.
46
What are the Tricyclic Antidepressants?
Amitriptyline** Clomipramine Imipramine Elavil Anafranil Tofranil **FOR PMS and Sleep
47
What is the concern with MAO inhibitors and vasoconstrictors?
Risk of hypertensive responses; use caution. Nardi, Parnate
48
How should vasoconstrictors be used with SNRIs?
Use cardiac dose of epinephrine; avoid synthetic vasoconstrictors. Celexa Prozac
49
Why is epinephrine contraindicated in thyrotoxicosis/hyperthyroidism?
Risk of exaggerated sympathetic effects, tachycardia, hypertensive episodes.
49
What is the dental treatment consideration after recent cocaine or methamphetamine use?
Postpone elective care for 24–72 hours due to hypertensive crisis and cardiac risks.
50
How should anesthetics be managed in patients with liver or kidney disease?
Use reduced doses; amides metabolized in liver may accumulate; consider alternatives.
51
Which anesthetic has a short duration of 20-40 minutes?
Mepivacaine 3% plain
52
Which anesthetics have an intermediate duration of 60-90 minutes?
Lidocaine with epinephrine, Articaine (septocaine), Prilocaine
53
Which anesthetic has a long duration of 90+ minutes and is not recommended for children?
Bupivacaine
54
Why is aspiration performed before injecting local anesthesia?
To prevent intravascular injection.
55
What should you do if aspiration is positive (blood is drawn into the syringe)?
Discard the needle and cartridge, then start over with new ones.
56
What are central nervous system (CNS) excitation signs of local anesthetic overdose?
Talkativeness, tremors, lightheadedness.
57
What are CNS depression signs of local anesthetic overdose?
Drowsiness, unconsciousness.
58
What cardiac symptoms can occur during local anesthetic overdose?
Palpitations, hypotension, bradycardia.
59
Drugs contraindicating vasoconstrictors:
Non-selective beta-blockers Tricyclic antidepressants MAO inhibitors SNRIs (caution) Cocaine/meth
60
What is the treatment for local anesthetic overdose?
Oxygen administration, vital signs monitoring, anticonvulsants, emergency response.
61
Armamentarium of local anesthesia:
Syringe (manual or self-aspirating) Cartridge (1.8 mL standard volume) Needle (short/long, various gauges) Topical anesthetics Cotton tip applicators, gauze
62
Needle safety:
Never recap with two hands Use scoop technique or safety shield Dispose immediately after use
63
Which way should the needle bevel face during injection to minimize tissue trauma?
The bevel should face the bone as it affects the direction and diffusion of the anesthetic.
63
What are the main parts of a local anesthesia syringe?
Piston, harpoon, barrel, thumb ring.
64
What are the main parts of a local anesthesia cartridge?
Diaphragm, plunger, rubber stopper, glass tube.
65
What are the main parts of a local anesthesia needle?
Hub, shaft, bevel.
66
Nerve anatomy and function:
Dendrites: receive stimuli Axon: transmits impulses Cell body: metabolic support
67
How are action potentials generated in nerves?
Via ion movement across the nerve membrane.
68
What ion influx causes depolarization during nerve conduction?
Sodium (Na⁺) influx.
69
What happens after depolarization in nerve conduction?
An impulse is transmitted along the nerve.
70
What is a nociceptor?
A specialized receptor that detects noxious (painful) stimuli.
71
What do nociceptors trigger?
Responses to potential or actual tissue damage.
72
What is acute pain?
Temporary pain directly related to injury that resolves with healing.
73
What is chronic pain?
Pain that persists beyond healing, becomes pathological, and may cause emotional and physiological effects like depression and insomnia.