Module 13 Flashcards
(43 cards)
Myoglobin and hemoglobin have the same
heme structure
What is a protein that stores and transports oxygen in muscles (i.e., heart and skeletal)?
myoglobin (Mb)
Cellular respiration
Energy production that occurs in the mitochondria
Myoglobin provides oxygen for what?
metabolic processes to convert/ produce energy
Functions of Myoglobin other than the primary function?
- provides oxygen for metabolic processes to convert / produce energy
- binds/ releases oxygen based on cellular oxygen concentrations (desaturates upon muscle activation and increases diffusion from capillaries to the cytoplasm)
3.used in the conversion of NO to nitrate to enhance cellular respiration
4.intercepts reactive oxygen species that produce unwanted metabolic products
what are the two primary functions of hemoglobin?
- Transports oxygen from the lungs to tissue
- Transports carbon dioxide from tissue to lungs
Does the transport of oxygen from the lungs to the tissue happen in arterial or venous circulation ?
Arterial circulation
high affinity for oxygen
low affinity for carbon dioxide, phosphates, hydrogen and chloride ions
Does the transport of carbon dioxide from tissue to lungs happen in arterial or venous circulation?
Venous circulation
High affinity for carbon dioxide, phosphates, hydrogen, and chloride ions
Low affinity for oxygen
Why does carbon want 4 bonds?
Hybridization-
forms sigma and pi bonds
1 S 3 2P will hybridize that contains Sp3 and explains why carbon wants 4 bonds
S orbitals like to form
Sigma bonds/ primary bond found in single bonds
P orbitals like to form
Pi bonds found in multiple bonds
Iron
Either Fe2+ or Fe3+
Ligands”________”(_______) to metal ion to stabilize charge and help solubilize.
“Bind” (coordinate)
Ligands are defined as
Electron- rich species (non metal or polyatomic ions)
How many coordination sites does a ligand contain?
Contains 6 coordination sites (based on hybridization of the metal center)
Ligands form stable ______ complexes
octahedral
What group is iron in?
Group 8
Electron configuration for Fe2+?
[Ar] 4s0 3d6
Electron configuration for Fe?
[Ar] 4s2 3d6
Iron is just _______ electron density from ligands.
accepting
Porphyrins are series of Hetero-cyclic macrocycles (tied together, > 10 atoms) composed of how many modified pyrrole subunits? connected by what?
4- connected by carbon bridges
Porphyrins are
highly conjugated aromatic compounds
Where are porphyrins found?
Mammals, plants, bacteria
Chrorophyl is a plant version of
our Heme- different metal/ purpose
