Module 2 Connective

Question 1

Macrophages are also known as

Answer 1

Histiocytes

Question 2

Component of a connective tissue consist of protein fiber and ground substance

Answer 2

Extra cellular matrix

Question 3

What germ layer is the origin of connective tissue

Answer 3

Mesoderm

Question 4

What embryonic tissue is the connective tissues derived?

Answer 4

Mesenchyme

Question 5

These cells have some features of smooth muscle cells, including actin-based contraction important fo woun contraction

Answer 5

Myofibroblasts

Question 6

Synthesize and secrete components of the ECM

Answer 6

Fibroblasts

Question 7

Most common connective tissue cell

Answer 7

Fibroblast/fibrocyte

Question 8

It has ovoid, large and pale staining nucleus, and basophilic cytoplasm due to the RER and golgi complex

Answer 8

Fibroblast

Question 9

Spindle-shaped with elongated dark nucleus and an acidophilic cytoplasm.

Answer 9

Fibrocyte

Question 10

Fused macrophages in connective tissues that functions in segregation and digestion of foreign bodies

Answer 10

Multinuclear giant cell

Question 11

Functions in the loclized digestion of bone matrix

Answer 11

Osteoclasts

Question 12

Adipocytes are found widely distributed in

Answer 12

Loose connective tissue

Question 13

Cells with eccentrically dark and cartwheel appearance nucleus, that fxns in chronic infection

Answer 13

Plasma cell

Question 14

What are the large masses of electron dense materials found in plasm cells

Answer 14

Russell bodies

Question 15

The mast cell granules contains:

Answer 15

Heparin
Histamine
Serotonin

Question 16

Mast cells functions mainly on

Answer 16

Anaphylactic rxns

Question 17

The most numerous fibers in connective tissue

Answer 17

Collagen

Question 18

What are the fibril forming collagens?

Answer 18

Type I,II,III,V,XI

Question 19

What type of collagen functions to resist tension commonly found in skin, tendon, bone

Answer 19

Type I

Question 20

What type of collagen functions to resist pressure commonly fd in cartilages.

Answer 20

Type II

Question 21

Type IV collagen belongs to what type of collagen fiber.

Answer 21

Sheet-forming collagen

Question 22

All basal lamina and external laminae is composed of what collagen fiber type that fxns s support of epithelial cells?

Answer 22

Type IV

Question 23

The linking or anchoring collagens consist of

Answer 23

Type VII, IX, XII, XIV

Question 24

A collagen synthesis defect disorder where there is a deletion of all or part of collagen alpha1 gene and type I collagen, with a symptom of spontaneous fractures

Answer 24

Osteogenesis impecfecta

Question 25

A collagen type III defect disorder manifested by hypermobility of digits and rupture of aorta or intestine

Answer 25

Ehlers-Danlos

Question 26

A disorder due to lack of vit.C taht leads to degeneration of ct and failure of wound healing

Answer 26

Scurvy

Question 27

The protein that gives the yellowish fresh tissue color of elastic fibers

Answer 27

Elastin

Question 28

These fibers can be stretched by a small force and return to its original form when the force is removed

Answer 28

Elastic fibers

Question 29

Reticular fibers are composed mainly of what type of collagen

Answer 29

Type III

Question 30

A carbohydrate moeity that reduces Ag+ of type 3 collagen to metallic silver

Answer 30

Argyrophilic

Question 31

True or false: reticular fibers forms coarse bundles

Answer 31

False: they form delicate networks not bundles

Question 32

Translucent matrix that surrounds the cells and fibers of connective tissues

Answer 32

Ground substance / matrix

Question 33

Extracellular matrix contains glycosaminoglycans such as

Answer 33

``` Hyaluronic acid Chondroitin sulfate Dermatan sulfate Kerratin sulfate Heparin sulfate ```

Question 34

Linear, very hydrophilic polysaccharides that are usually bound covalently to protein core as part of proteoglycan

Answer 34

Glycosaminoglycan

Question 35

Small glycosylated proteins containing numerous binding sites to cells, ignalling molecules

Answer 35

Multiadhesive glycoproteins

Question 36

Multiadhesive glycoproteins important for adhesion of epithelial cells to basal lamina via tm integrin receptors

Answer 36

Fibronectin and laminin

Question 37

Specific type of connective tissue that surrounds blood vessels and nerves and fills unoccupied spaces

Answer 37

Loose connective tissue

Question 38

When collgen is denatured by boiling, it yields

Answer 38

Gelatin