Module 3 Flashcards
biological aging
refers to the structural and functional changes that occur in an organism overtime. Biological aging is associated with increased vulnerability on the body and increased rates of disability
environmental theories of aging
- Wear and tear
○ The body operates similar to a machine and wears out overtime- Somatic mutation theory
○ Harmful mutaions caused by enviormental stressors accumulate with age and damage somatic cells
- Somatic mutation theory
developmental and genetic theories of biological aging
- Autoimmune theory
○ Overtime the immunse systems potective reaction declines and the system looses its ability to distinguish between self and non self- Cross linkage theory
○ As we age the body accumulates cross linked collagen which makes tissue stiffer and results in changes to the body - Neuroendocrine theory
○ Functional loss of neurons and their hormones is central to the aging process - Free radical theory
○ Unstable free radicals can damage cells or cause cell mutations - Genetic control theory
○ Genetic control is programmed into every cell in our bodies creating a blueprint for aging
- Cross linkage theory
impacts on hair and skin
- Hair
○ Decrease in number of pigment producing cells cases greying anf ahir becomes white when melanocytes completely stop working
○ In men as interaction between testosterone and othe rgenes- Skin
○ Wrinkles and sagging caused by loss of elasticty and salt deposits
○ Discolouration known as lentigo and is caused by the accumulation of melatonin
Senile purpura are bruises where blood vessels have ruptured
- Skin
nervous system
Neurons carry messages across the nervous system as electric signals, as peopleage neurons are lost which affects functions
parkinsons disease
- Parkisons disease
○ Age related illness that occurs due to slow death of the nerve cells in our brains
○ Neurological disease most commonly occurs in older people and the exact cause is unknown
Most common symptoms is tremours
falls
○ Cerebellum is repsonsible for movements and balance and a 25% loss of neurons occurs in the cerebellum as we age
○ Falls are serious for older dults and a substantial cost for the healthcare system
Result in broken/fractured bones, functional limitations, hospitalization and death
sleep
○ Poor sleep quality and insomnia common for older adults
○ Sleep is regulated by the arousal and sleep producing systems in the brain stem
○ 2 stages are slow wave and rem sleep, older adults have less rem sleep
sensory system-vision and hearing
- Vision and hearing
○ Most commonly affected vision and hearing
○ Prebyopia: inability to focus on near objects
○ Presbycusis: normal hearing loss that occurs with age
○ Cataracts occrs when the lens of the eye becomes cloudy
○ Glucoma incloves increased pressure in the eye due to dluid buildup and can cause blindess
§ Treated by surgery or eye drops
sensory system- smell, taste, touch
○ We can lose some of our sesnes of smell and taste, which can lead to poor nutrional practices
○ Body loses the ability to regulate hot and cold as well, due to loss of fatty tissue and decrased blood circulation
○ Inability to adequetly cool down is due to fewer functional sweat glands
skeletal and muscular systems
- Osteoporosis is a disease resulting in severe bone loss where bones become thin and porous
○ Beginsg with bone loss and in late stages can lead to loss of height, back pain, and curving of the back and spine
○ Women 4x more likley- Arthritis is a condtion charachterized by joint inflammation resulting in pain, swelling, and deformity, most common cuase of disability in old age
○ Most common type is osteoarthritis
○ Rheumatoid arthritis occurs when the immune system attacks synovial membranes - Muscle strneth
○ As people age they expereince a loss in muscle strnegth that become nticable around age 50
○ Muscle atrophy can also occur if muscles are not used for long periods of time
- Arthritis is a condtion charachterized by joint inflammation resulting in pain, swelling, and deformity, most common cuase of disability in old age
reproductive systems
- Female
○ Menopause: the permanent stoppage of the mentrual cycle and end of fertility
○ Results in end of ovulation and decline in estrogen and progesterone
○ Symptoms include mood swings, hot flashes, irritability, fatigue, and anxiety- Male
○ Testerone levels begin to decline around age 50 or 60
○ Begin postatic hyperplasia is an enlarged prostate resulting in the need to urinate more frequently and erectile dysnfunction
- Male
cardiovascular system
- Function is to provide oxygen and nutrients to cells and carry away waste
- Hypertension and atherscolorisis become more common
○ Builduo of plaque creates blockages in the coronary arteries and heart attacks can occur
○ Treatments include coronary bypass surgery and angioplasty
○ Congestive heart failure occurs when the heart is not able to pump enough blood for the body - Risk factors include: lack of exersice, stress, obesity, smoking and low socioeconimic staus
- Hypertension and atherscolorisis become more common