Module 3 Blueprint Flashcards
the kidneys are responsible for
filtering water and wastes from the blood stream
what are the functions of the kidney
maintaining body fluid volume, creating urine, regulating blood pressure, acid-base balance, produce erythropoietin, and convert vitamin D
what is renal agenesis
person born with only one kidney
what is kidney dysplasia
born with two kidneys but only one yes
What is the functional unit of the kidney
the nephron
What does the nephron do
forms urine by filtering waste products and water from the blood
what do juxtaglomerular and macula densa cells do
macula densa: detects changes in blood volume and pressure
juxtaglomerular: produce renin
what does renin regulate
blood flow, glomerular filtration rate, and blood pressure
when is renin produced by the juxtaglomerular cells
blood volume, blood pressure, or sodium levels are low
explain the RAAS system
renin –> angiotensinogen –> angiotensin 1 –> angiotensin 2 –> aldosterone
what does aldosterone do
increase kidney reabsorption of sodium and water, promotes excretion of potassium
explain blood supply through the nephron
afferent arteriole -> glomerulus (water and small particles filtered to make urine) –> proximal convulated tubule–> descending loop of henle –> ascending loop of henle –> distal convoluted tubule –> collecting duct
the remaining blood not filtered in the glomerulus leaves through the
efferent arteriole
the regulatory function of the kidney controls
fluid and electrolyte, acid and base balance
the hormonal functions of the kidney control
RBC formation, blood pressure, and vitamin D activation
the kidneys can manage regulatory functions through urine elimination. What are the processes involved in urine elimination
glomerular filtration, tubular reabsorption, tubular secretion
what particles are allowed to be filtered across the glomerular membrane to form glomerular filtrate?
water, electrolytes, other small particles (creatinine, urea nitrogen, glucose)
What particles are too large to be filtered through glomerular capillary walls and are not commonly found in urine
blood cells, albumin, other proteins
Normal glomerular filtration rate
125 mL/min
How many L/day do we excrete in urine and why?
1-3L/day to prevent dehydration, much of waste produced by glomerulus is reabsorbed
GFR is controlled by
blood pressure and blood flow (the kidneys regulate their own blood pressure to keep GFR constant)
How do the kidneys control their own blood pressure
dilating and constricting the afferent and efferent arteriole
“when the systolic blood pressure drops below 65-70 mmhg”
“self regulation processes do not maintain GFR”
What is the second process in urine formation
tubular reabsorption