Module 4

Question 1

What percentage of women over the age of 50 and the US will experience at least one fragility fracture in their lifetime

Answer 1

Forty

Question 2

Women age 50 and under and men age 70 and under consume how many milligrams of calcium per day

Answer 2

1000

Question 3

Men age 71 or older and women age 51 or older should consume how many milligrams of calcium per day

Answer 3

1200

Question 4

For everyone under the age of 50 how many International units of vitamin D are recommended A-day

Answer 4

400 to 800

Question 5

For everyone over the age of 50 how many IU of vitamin D do they recommend per day

Answer 5

800 to 1000

Question 6

True or false Vitamin D is necessary for the absorption of calcium

Answer 6

True

Question 7

What are the most common calcium supplements used

Answer 7

Calcium carbonate and calcium citrate

Question 8

What are the most common vitamin D supplements used

Answer 8

Vitamin D2 or ergocalciferol and vitamin D3 cholecalciferol

Question 9

What is the number one cause of fragility fractures

Answer 9

Falls

Question 10

The NOF States that the most effective fall Prevention exercise plan includes

Answer 10

Twice weekly exercise for at least 6 months with a minimum of 50 hours of exercise

Question 11

Bone formation and bone resortion that should be happening simultaneously is called what?

Answer 11

Bone remodeling

Question 12

The best marker for bone formation

Answer 12

N-terminal propeptide

Question 13

10 year hip fracture probability of more than 3% or a 10 year osteoporosis related fracture probability greater than 20%

Answer 13

FRAX

Question 14

What are the 2 types for drug therapy

Answer 14

Antiresorpative or bone forming medication

Question 15

Name some of the antiresorpitive drugs

Answer 15

Bisphosponates, RANK inhibitor denosumab, estrogen or hormone replacement therapy, calcitonins, SERMS

Question 16

Types of bone forming medications

Answer 16

Steroid therapy’s, analogies of parathyroid hormone or PTH, teriparatide, Forteo

Question 17

These types of medicines work to slow down the process of bone resorption and by binding to the hydroxapatite surface of bone

Answer 17

Bisphosphonates

Question 18

4 types of Bisphosphonates Medication

Answer 18

Fosamax(alendronate) Boniva(ibandronate)
Actonel(Risedronate)
Reclast(zoledronic acid)

Question 19

32 amino acid polypeptide hormone that the human thyroid produces to regulate calcium and phosphate levels

Answer 19

Calcitonin

Question 20

Name the 2 types of Calcitonin

Answer 20

Fortical
Miacalcin

Question 21

SERM

Answer 21

Selective estrogen receptor modulators

Question 22

SERM drug

Answer 22

Raloxifene

Question 23

True or false the fda has approved estrogen and hormone replacement therapies as a way to prevent osteoporosis

Answer 23

True

Question 24

This is a 84 amino acid polypeptide that is naturally produced by the parathyroid gland

Answer 24

Parathyroid hormone

Question 25

This drug is created using the 1st 34 amino acid groups of the 84 amino acid chain of natural parathyroid hormones

Answer 25

Teriparatide

Question 26

When RANK binds with RANKL what happens

Answer 26

Activates osteoclast activity Which responds with reabsorbing bone mass

Question 27

RANK inhibitor

Answer 27

Denosumab (Prolia)

Question 28

What is the most efficient dose of calcium Absorption supplements

Answer 28

500 to 600 mg

Question 29

Osteoanabolic drug

Answer 29

Teriparatide

Question 30

This is a severe side effect of bisphosphonate use

Answer 30

Osteonecrosis of the jaw

Question 31

How do selective astrogen receptor modulators reduce the risk of breast cancer

Answer 31

They block the effect of estrogen on the breast tissues

Question 32

Estrogen is approved by the fda for the treatment of osteoporosis in post menopausal women

Answer 32

False

Question 33

Overall medication regimen compliance for osteoporosis medication is about what %

Answer 33

65%