Module 4 Flashcards
(48 cards)
Insomnia
- Difficulty falling asleep or staying asleep
- The m/c sleep related complaint
Narcolepsy
- Falling asleep unexpectedly (REM w/in 15 min)
- dysfunction of processes that regulate sleep/wake
- excessive daytime sleepiness = m/c complaint
Intracellular Fluid
- def
- fraction & volume
- fluid within the cells
- 2/3 of total body water = ~28 L
Extracellular Fluid
- def
- fraction & volume
- sub cat (3)
- Fluid outside of the cells
- 1/3 of total body water = ~14 L
- Interstitial, intravascular, transcellular
Interstitial Fluid
- def
- volume
- Fluid between cells and outside blood vessels (included lymph)
- ~11 L
Intravascular Fluid
- Def
- volume
- blood plasma within vascular system
- ~3 L
Transcellular fluids
- def
- ex (5)
- Secreted by epithelial cells
- CSF, pleural, peritoneal, pericardial, synovial
Hypotonic Solution
- meaning
- effect
- ex of solution
- Solution has fewer particles
- Water goes into cell = cell expands
- 0.45 % sodium chloride (anything less than 0.9% NaCl)
Hypertonic Solution
- meaning
- effect
- ex. of solution (3)
- Solution has more particles
- Water moves out of cells = cell shrinks
- 3% sodium chloride, D10W, 5% dextrose in any type of NaCl
Isotonic Solution
- meaning
- effect
- ex. of solution (3*)
- equal number of solutes in and out of cell
- equal movement of water in & out of cell = no net change
- 0.9 % sodium chloride, Lactated Ringers, D5W (starts isotonic but dextrose leaves quickly)
Extracellular fluid volume deficit
- aka
- meaning
- association with sodium
- treatment
- Hypovolemia
- Not enough fluid in extracellular compartment (vascular & interstitial)
- Occurs with hypernatremia
- Tx: normal saline
Hypernatremia & ECF Volume Deficit
- why they occur together
- Hypernatremia = volume goes down and high level of sodium is left
- Pulls water out of cells = cells shrink
Clinical Dehydration
- 2 components
- ECF deficit & hypernatremia
Manifestations of ECF Volume Deficit/Dehydration
- Sudden change in BW (decrease)
- Increase in HR
- Decrease in BP
- Increase in RR
- Decreased cerebral perfusion (check LOC, PERRLA, mm strength, reflexes)
- Skin = cool/moist
Respiratory Acidosis
- what’s happening
- causes
- lungs are unable to excrete CO2 & H20
- anything that causes hypoventilation (head injury, narcotics, pneumonia)
Respiratory alkalosis
- what’s happening
- causes
- lungs excrete too much C02 and H20
- anything causing hyperventilation (anxiety, pain, fever = increased metabolic demand)
Metabolic Acidosis
- what’s happening
- causes (5)
- Increase of metabolic acid or decrease of base
- DKA, renal failure, starvation, APAP OD, diarrhea (lose HCO3)
Metabolic Alkalosis
- what’s happening
- causes (3)
- Direct increase of base or decrease of metabolic acid
- Vomit, Excess of antacids, gastric suction
Respiratory Acidosis
- expected pH: 7.35 - 7.45
- expected PaCO2: 35-45
- expected HCO3: 21-28
- uncompensated v partially compensated
- uncompensated: low pH, high PaCO2, no change in HCO3
- partially: low pH, high PaCO2, high HCO3
Respiratory Alkalosis
- expected pH: 7.35 - 7.45
- expected PaCO2: 35-45
- expected HCO3: 21-28
- uncompensated v partially compensated
- uncompensated: high pH, low PaCO2, no change in HCO3
- partially: high pH, low PaCO2, low HCO3
How to decide between respiratory and metabolic acidosis/alkalosis
- Respiratory: inverse relationship between pH and PaCO2
(If pH goes up, PaCO2 will go down) - Metabolic: pH and HCO3 will move together
(if pH goes up, HCO3 will go up)
Patient 1
pH 7.32
PaCO2 48 mm Hg
HCO3 25 mEq/L
Uncompensated respiratory acidosis
Patient 2
pH 7.48
PaCO2 32 mm Hg
HCO3 20 mEq/L
Partially compensated respiratory alkalosis
Metabolic Acidosis
- expected pH: 7.35 - 7.45
- expected PaCO2: 35-45
- expected HCO3: 21-28
- uncompensated v partially compensated
- uncompensated: low pH, no change PaCO2, low HCO3
- partially: low pH, low PaCO2, low HCO3