Module 4: Reproductive system Flashcards

1
Q

What does the ovaries contain

A
  • stromal matrix
  • Follicles
  • tunica albuginea
  • surface epithelium
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2
Q

What are the hormones involved in the repro system

A

•Gonadotropin-releasing hormone (GnRH)
•Follicle-stimulating hormone (FSH)
•Luteinizing hormone (LH)
•Inhibin*
Sex hormones:
•Testosterone
•Estrogens and Progesterone

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3
Q

What type of estrogen is most abundant and most responsible for estrogenic effects

A

Estradiol

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4
Q

What are the three key differences between spermatogenesis and oogenesis

A

•Production of oocytes only occurs in fetus
•In primary oocytes, meiosis is arrested in late prophase I and resumes years later
•In secondary oocytes, meiosis is arrested at metaphase II and is only completes if fertilisation occurs

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5
Q

True/False

Primordial follicles have a single layer of squamous pre-granulosa cells surrounding a primary oocyte.

A

True

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6
Q

True/False

Primary follicles have a double layer of cuboidal pregranulosa cells surrounding a primary oocyte.

A

False

Single layer of cuboidal pregranulosa cells

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7
Q

True/False

Secondary follicles have multiple layers of granulosa cells surrounding a primary oocyte.

A

True

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8
Q

Describe the Vesicular follicles structure

A

Fluid-filled cavity called antrum.

Just before ovulation, the primary oocyte inside the vesicular follicle resumes meiosis and becomes a secondary oocyte.

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9
Q

Apoptosis

A

Programmed cell death

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10
Q

In which region of the fallopian tube does fertilisation take place

A

Ampulla

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11
Q

In which region of the fallopian tube does sperm capacitation take place?

A

Isthmus

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12
Q

Fill in the blanks:
High estrogen levels result in …. cilia beat frequency and smooth muscle … in fallopian tubes

A
  • increased
  • contraction
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13
Q

True/False
High progesterone levels result in decrease cilia beat frequency and smooth muscle relaxation in the fallopian tubes.

A

True

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14
Q

True/False
The prostate gland produces 70% of fluid volume in the seminal fluid

A

False
25%

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15
Q

True/False
Prostate gland produces proteases that fluidize the ejaculation

A

True

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16
Q

True/False
Prostate gland produces mucus secretion that lubricates the gland penis

A

False

17
Q

True/False
Prostate gland produces fructose-rich secretion for energy production

A

False

18
Q

True/False
The corpus spongiosum is erectile tissue within the penis that becomes engorged with blood, allowing an erection to occur.

A

False
Corpora canvernosa only

19
Q

3 Common causes of female infertility

A

Tubal disease/blockage
Endometriosis
Premature ovarian failure
Hypothalamic disfunction

20
Q

Applying your knowledge of how gonadotropins act on follicle cells to regulate ovarian function, describe what you think a daily injection of FSH for 8 to 10 days, Followed by an injection of LH, might do in a treatment schedule for in vitro fertilisation

A

FSH is for growth of follicles [0.5 marks]; acts on granulosa cells to drive conversion of androgens to estrogens [0.5 marks] which drives proliferation of the granulosa cells [0.5 marks]; injection of LH provides LH surge [0.5 marks] that triggers resumption of meiosis which is required before the oocyte can be fertilised [0.5 marks] + 0.5 marks for clear understanding [3 marks totall