Module 7: Renal Physiology Flashcards

1
Q

site of glomerular filtration

A

renal corpuscle

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2
Q

site of reabsorption and secretion

A

bowman’s capsule

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3
Q

establishes the hyperosmotic medullary gradient

A

loop of henle

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4
Q

bulk reabsorption of solutes and water

A

proximal tubule

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5
Q

fine-tuning of solute reabsorption/secretion

A

distal tubule and cortical collecting duct

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6
Q

movement of a substance from the tubule to the peritubular capillaries

A

basic renal process of tubular reabsorption

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7
Q

movement of a substance from the peritubular capillaries to the tubule

A

basic renal process of tubule secretion

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8
Q

filtration of plasma from glomerular capillaries into bowman’s space

A

basic renal process of glomerular filtration

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9
Q

mechanisms of tubular reabsorption

A

diffusion down concentration gradient
mediated transport

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10
Q

movement into interstitial fluid along concentration gradient
movement from interstitial fluid to blood by bulk flow or diffusion

A

diffusion down concentration gradient

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11
Q

requires active transport and energy
1 degree transcellular

A

mediated transport

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12
Q

types of mediated transport

A

Na/K - ATPase
Na/glucose
Na/AA Co-transport

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13
Q

Na tubular reabsorption is an example of

A

active transport

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14
Q

maximum amount of material that can be transported per unit time
occurs when binding sites on transport protein are saturated

A

transport maximum

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15
Q

secondary active transport or water soluble vitamin are examples of

A

transport maximum

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16
Q

dilation of the efferent arteriole causes DECREASED glomerular filtration rate (GFR) by

A

decreasing glomerular capillary hydrostatic pressure

17
Q

substance that is freely filtered, not reabsorbed and not secreted

A

inulin

18
Q

substance that is freely filtered, not reabsorbed and not secreted can be used to determine the
following normal renal function value

A

125mL/min glomerular filtration

mL/min!!!!

19
Q

substance that is freely filtered and 100% secreted

A

creatinine

20
Q

substance that is freely filtered and 100% secreted measures which of the following renal functional
parameters

A

renal plasma flow

21
Q

key factor necessary for the generation of hyperosmotic urine by the countercurrent
multiplier system

A

active transport of sodium in the ascending limb of the loop of henle

22
Q

renal hormone responsible for the formation of Angiotensin I

A

renin

23
Q

steroid hormone made by the adrenal cortex, helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body

A

aldosterone

24
Q

controls na+ absorption

A

aldosterone
ANP at tubules

25
Q

directly alters aldosterone secretion

A

angiotensin II

26
Q

water is reabsorbed in

A

proximal tubule
descending limb of loop of hence
ureter

27
Q

water is NOT reabsorbed in

A

ascending limb of loop of hence

28
Q

production of hypoosmotic (dilute) urine requires

A

low vasopressin

29
Q

results from decreased solute reabsorption, decreased water reabsorption, increased solute excretion

A

osmotic diuresis

30
Q

the HCO3- buffering system is highly effective because

A

the elimination of CO2 in the lungs

31
Q

is compensated by decreasing HCO3- recovery

A

respiratory alkalosis

32
Q

will cause a pH <7.4

A

hyporventilation

33
Q
A